Navigation Links
New Consortium Paves the way for Improved Treatment of Hypertension and Associated Vascular Complications
Date:11/17/2009

LEIDEN, The Netherlands, November 17 /PRNewswire/ -- Top Institute Pharma (TI Pharma) has formed a consortium with Actelion Pharmaceuticals Ltd, Erasmus Medical Centre and Maastricht University to define new modalities for the treatment of hypertension (high blood pressure) and associated vascular complications such as heart and kidney failure, myocardial infarction and stroke. Based on novel action mechanisms, new drugs may be discovered with the potential to prevent vascular complications in patients with hypertension: an opportunity to improve the quality of life for over a billion people worldwide. This collaboration, involving 3.4 million euros, 9 new research positions, unique materials and exchange of know-how, is scheduled to last 3 years.

Jan Danser, Professor of Pharmacology at Erasmus MC says: "Ideally, new antihypertensive drugs not only lower blood pressure, but also offer organ protection. Our project studies the consequences of blocking the biological pathways in cells and organs that lead to hypertension. As such, the project will pave the way towards finding new ways to better treat hypertension and its associated vascular complications." Additionally, the project will focus on finding new modalities for the treatment of fibrosis and pulmonary hypertension, especially in children.

Hypertension, or high blood pressure, is a leading risk factor for coronary heart disease, renal insufficiency, pulmonary fibrosis and stroke. Hypertension often results in vascular complications and end-organ damage: major organs like the heart, kidneys, lung, brain and eyes, which are fed by the circulatory system, are affected by fluctuations in blood pressure. The number of people suffering from high blood pressure worldwide is increasing: 1 billion people are currently affected, but estimates predict that in 2025 the number will exceed 1.5 billion. Despite the high occurrence and sometimes great burden of the disease, available treatments are far from being sufficient. For children suffering from hypertension, an adequate treatment does not even exist.

The Netherlands Heart Foundation also supports this research. Hans Stam, director of the Netherlands Heart Foundation says: "Hypertension is a major risk factor for cardiovascular diseases such as myocardial infarction, heart failure and stroke. Unfortunately, antihypertensive medication fails to lower blood pressure sufficiently in numerous cases. For instance, research funded by the Netherlands Heart Foundation showed that 25% of the patients did not benefit from treatment with ACE inhibitors. An effective treatment of hypertension is of the utmost importance in our battle against cardiovascular diseases. The Netherlands Heart Foundation welcomes this new consortium and its efforts to explore new and more effective hypertension therapies."

SOURCE Top Institute Pharma (TI Pharma)


'/>"/>
SOURCE Top Institute Pharma (TI Pharma)
Copyright©2009 PR Newswire.
All rights reserved

Related biology technology :

1. TargetEx Leads the European Cancer Research Consortium
2. Ricardo Launches Consortium to Evaluate Lubricant Challenges of Future Low Carbon Engine Technologies
3. International science consortium publishes analysis of domestic cattle genome sequence
4. PCI Biotech-led Consortium Awarded EUR1.1 m Eurostars Grant for siRNA
5. NewCardio Joins the Cardiac Safety Research Consortium
6. Genstruct Added to The Biomarker Consortiums Rapidly Growing Roster of Industry Experts
7. RainDance Technologies Signs a Collaboration Agreement with sanofi-aventis and Louis Pasteur University to Launch dScreen Consortium within ALSACE BIOVALLEY cluster
8. Noted Molecular Epidemiologist Joins Cepheid to Head Healthcare Associated Infection Consortium Program
9. Sigma-Aldrich Joins Phase 2 of The RNAi Consortium to Validate shRNA Libraries
10. The Scripps Translational Science Institute Joins The MetaMiner Cardiac Consortium
11. Advanced Energy Consortium will develop micro and nanosensors to boost energy production
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/10/2017)... , Oct. 10, 2017 SomaGenics announced the ... NIH to develop RealSeq®-SC (Single Cell), expected to be ... small RNAs (including microRNAs) from single cells using NGS ... the need to accelerate development of approaches to analyze ... "New techniques for measuring levels of mRNAs ...
(Date:10/10/2017)... ... October 10, 2017 , ... The Pittcon Program ... honoring scientists who have made outstanding contributions to analytical chemistry and ... 2018, the world’s leading conference and exposition for laboratory science, which will be ...
(Date:10/9/2017)... ... , ... The award-winning American Farmer television series will feature 3 Bar Biologics ... at 8:30aET on RFD-TV. , With global population estimates nearing ten billion people ... to feed a growing nation. At the same time, many of our valuable resources ...
(Date:10/9/2017)... ... October 09, 2017 , ... The ... medical marijuana products targeting the needs of consumers who are incorporating medical marijuana ... place in Phoenix, Arizona. , As operators of two successful Valley dispensaries, The ...
Breaking Biology Technology:
(Date:4/5/2017)... , April 4, 2017 KEY FINDINGS ... anticipated to expand at a CAGR of 25.76% during ... diseases is the primary factor for the growth of ... report: https://www.reportbuyer.com/product/4807905/ MARKET INSIGHTS The global ... product, technology, application, and geography. The stem cell market ...
(Date:3/30/2017)... The research team of The Hong Kong Polytechnic University (PolyU) ... ground breaking 3D fingerprint minutiae recovery and matching technology, pushing contactless ... use in identification, crime investigation, immigration control, security of access and ... ... A research team led by Dr Ajay Kumar ...
(Date:3/27/2017)... , March 27, 2017  Catholic Health Services ... Management Systems Society (HIMSS) Analytics for achieving Stage ... Model sm . In addition, CHS previously earned ... hospitals using an electronic medical record (EMR). ... high level of EMR usage in an outpatient ...
Breaking Biology News(10 mins):