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New Clinical Studies Presented at the American Society of Anesthesiology (ASA) Annual Meeting Show Masimo Technologies Provide Advanced Clinical Intelligence
Date:10/23/2008

sebbe at Louis Pradel Hospital in Lyon-Bron, France, studied the ability of PVI to predict the effects of positive end-expiratory pressure (PEEP) on cardiac index (CI) in 21 mechanically-ventilated patients following cardiac surgery. The clinical team recorded mean arterial pressure (MAP), central venous pressure (CVP), cardiac index (measured using pulmonary artery catheter), and PVI at three successive tidal volume settings (6, 8, and 10 ml/kg) under zero end-expiratory pressure and following adjunction of a PEEP, and found that successive zero end-expiratory pressure induced significant changes in PVI, but not CVP or MAP. Findings also showed that "PVI was able to predict the hemodynamic effect of PEEP with 73% sensibility and 80% specificity." Researchers concluded that PVI could allow clinicians to "optimize fluid loading noninvasively before adding PEEP for pulmonary reasons."

Pulse Oximeter Perfusion Index as a Predictor for the Effect of llio-Inguinal Block(4), a prospective clinical study led by Dr. AKI Uemura at the Tsukuba University Hospital in Ibaraki, Japan, examined whether changes in Perfusion Index (PI) reflect the effect of llio-inguinal block in 18 children (mean age 32 months) during inguinal herniorrhaphy. Patients receiving llio-inguinal blocks were divided into two groups according to the concentration of Ropivacaine received (0.25% or 0.5%), and monitored using electrocardiography, noninvasive blood pressure, and two Masimo SET Radical pulse oximeters placed on both the left and right side limb. The clinical team recorded PI, blood pressure, heart rate, end-tidal CO2, end-tidal Sevo%, and respiratory rate for all patients and found that PI on the block side was significantly elevated when compared to the non-block side. Researchers concluded that "PI value is a useful, objective, and noninvasive method to evaluate the effect of llio-inguinal block in pediatric patients."

In addition, there were nine other clinical studies(5-13)
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