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New Assay Detects 100 Percent of Stage I, II and III Colon Cancers in Pre-Clinical Trials
Date:9/16/2009

0 freshly drawn serum samples. ColoMarker, which uses a proprietary biomarker developed by EDP, had an overall accuracy rate of 93 percent.

When compared to the Fecal Occult Blood (FOB) test, the current clinical standard test recommended for colon cancer screening, ColoMarker performed extremely well, according to Jones. In a test panel of 243 samples drawn from patients who exhibited possible colon cancer and were referred to a specialist, the false positive rate was significantly lower for the ColoMarker assay (11 percent) than for the FOB assay (30 percent). Notably, the ColoMarker assay detected 100 percent of early-stage (Stage I) colon cancer; the FOB assay missed about 60 percent.*

"The FOB test is not 'patient friendly,' meaning that most people either refuse to use the test or cannot collect the sample effectively," continued Jones. "ColoMarker is the first 'blood-based' assay that will simplify the whole process for both patients and doctors."

The ColoMarker assay currently tests a serum sample on a microtiter plate ELISA platform.

EDP has applied for patents on the reagents and assay, and is moving toward next steps for the commercialization of the test.

About EDP Biotech

EDP Biotech Corporation is a privately held medical device company focused on the development and sale of immunodiagnostic tests for both humans and animals. EDP utilizes more than 30 years of research and development in identification and purification of proteins present in the early stages of biological changes for production of in vitro diagnostic tests whose primary target is early detection.

*The reported results for the FOB test were lower than seen in other studies. The patients used for the study may have caused this. The false positive rate on FOB for patients referred to a GI specialist is higher than seen for the general population. Even fo
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SOURCE EDP Biotech Corporation
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