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New Applications of Pressure BioSciences' PCT Platform Prominently Featured at Scientific Conference on Technologies for Protein Research
Date:3/19/2013

data on the comparison of embryonic and IPSC stem cell lines.  Cell lysis (i.e., breakage), an important part of the study's workflow, was routinely performed by Dr. Pripuzova and her colleagues using PCT in PBI's Barocycler instrument and consumables.

Dr. Zongming Fu , a member of Professor Jennifer Van Eyk 's proteomics lab at the Johns Hopkins University School of Medicine, presented data on improved protein extraction and identification from archival formalin-fixed paraffin-embedded ("FFPE") human aorta samples using high heat combined with PCT.  Dr. Fu and his colleagues found that high heat combined with PCT increased protein extraction yield over heat alone, resulting in a greater number of protein identifications.  They concluded that this method now makes it feasible to test archives of FFPE arterial and aorta samples, including rare and difficult tissues, for biomarker discovery. 

Dr. Nate Lawrence , Vice President of Sales and Marketing for PBI, commented: "We are very pleased that such highly respected protein scientists recognize the advantages of PCT in their work.  First, the use of PCT to prepare stem cells for analysis opens up a new field for us, one in which we believe a focused marketing effort will result in increased PCT instrument sales in the short term.  Second, we believe the data on enhanced protein recovery from FFPE samples support the continued development of our PCT-based FFPE extraction system, which we expect to release later this year, and that we expect to have a positive impact on sales in 2013 and beyond."

Dr. Lawrence continued: "Mass spectrometry-based protein analytical methods have begun to move into the personalized medicine field.  These diagnostic and prognostic tools offer the potential to save many lives and greatly improve therapeutic outcomes.  The PCT-SWATH method int
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SOURCE Pressure BioSciences, Inc.
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