Navigation Links
Neuroscience method of optogenetics as good as electrical stimulation
Date:12/12/2013

ation method compared to no stimulation were small, but statistically significant. When the T was in the receptive field, one research subject became 10 percentage points more accurate (80 percent vs. 70 percent) when optically stimulated and eight points more accurate when electrically stimulated. The subject was five points less accurate (73 percent vs. 78 percent) with optical stimulation and six percentage points less accurate with electrical stimulation when the distracting character was in the receptive field.

The other subject showed similar differences. In all, the two primates made thousands of choices over scores of sessions between the T and the distracting character with either kind of stimulation or none. Compared head-to-head in a statistical analysis, electrical and optical stimulation showed essentially similar effects in biasing the decisions.

Optical advantages

Although the two methods performed at parity on the main measure of accuracy, the optogenetic method had a couple of advantages, Sheinberg said.

Electrical stimulation appeared to be less precise in the cells it reached, a possibility suggested by a reduction in electrically stimulated subjects' reaction time when the T appeared outside the receptive field. Optogenetic stimulation, Sheinberg said, did not produce such unintended effects.

Electrical stimulation also makes simultaneous electrical recording very difficult, Sheinberg said. That makes it hard to understand what neurons do when they are stimulated. Optogenetics, he said, allows for easier simultaneous electrical recording of neural activity.

Sheinberg said he is encouraged about using optogenetics to investigate even more sophisticated questions of cognition.

"Our goal is to be able to now expand this and use it again as a daily tool to probe circuits in more complicated paradigms," Sheinberg said.

He plans a new study in which his group will look at me
'/>"/>

Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert  

Page: 1 2 3 4

Related biology technology :

1. Elsevier and the Neuroscience Information Framework Work Together to Improve Reporting of Research in Neuroscience Literature
2. CIRTEMO to Launch Multivariate Optical Element Platform for Neuroscience Applications
3. Pipette.com Announces Promotional T-Shirt and Other Specials for Neuroscience 2013
4. Elekta Opens Global Education Center for Oncology and Neuroscience Professionals
5. Saint Lukes Neuroscience Institute Announces 2013 Symposium
6. Blanchette Rockefeller Neurosciences Institute Partners with Neurotrope BioScience to Advance New Alzheimers Disease Discoveries
7. Biotrial, a Successful Leading CRO, Continues to Expand its Activities, Creating a Unique Neuroscience Pool of Talent and Capabilities: Biotrial Neuroscience
8. Intellect Neurosciences, Inc. to Present at Neurotech Investing and Partnering Conference
9. Trinity College Dublins Neuroscience and Bioengineering Programmes Receive Postgraduate Course of the Year Awards
10. Intellect Neurosciences Adds Two New Tau Programs to its Alzheimers Disease Development Pipeline
11. Intellect Neurosciences Enters Collaboration Agreement with Leading Alzheimers Research Group at University of California Irvine to Test First in Class Dual Target Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Neuroscience method of optogenetics as good as electrical stimulation
(Date:8/21/2014)... N.Y. (PRWEB) August 21, 2014 The ... the first private college in the Mid-Hudson Region to ... will now begin accepting applications from qualified “high-technology” businesses ... “We are very pleased to have been selected for ... Governor Cuomo’s transformative initiative to stimulate economic development in ...
(Date:8/21/2014)... Mathematic studies at the Program for Evolutionary ... by the Jeffrey Epstein VI Foundation , have shown ... identified for elimination. These aggressive cells are the driver mutations ... topological map of what to look for when examining tumors, ... tumor cells can be extracted from biopsy, it,s very difficult ...
(Date:8/21/2014)... Cord Blood Corporation (NYSE: CO ) (the ... for the first quarter of fiscal year 2015 on ... US.  The Company will host a ... 29, 2014 to discuss its financial performance and give ... by a question and answer session.  Interested parties may ...
(Date:8/21/2014)... Pursuit Solutions ( http://www.pursuit-solutions.com ), ... services for Life Sciences sales and marketing organizations, ... New Commercial Sales Models” by Peter Robinson, co-founder ... article examines some innovative models used to improve ... in the pharmaceutical market. Robinson grades the industry ...
Breaking Biology Technology:The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 2The College of New Rochelle Becomes First Private College in Mid-Hudson Region to Earn START-UP NY Designation 3Science Power Jeffrey Epstein and Harvard University Fund Project to Visually Stop Tumor Growth 2China Cord Blood Corporation to Report First Quarter of Fiscal 2015 Financial Results 2Pursuit's Peter Robinson Publishes "Grading Pharma's Use of New Commercial Sales Models" 2
... Drug Discovery Capabilities, INDIANAPOLIS, and SAN DIEGO, July ... and SGX Pharmaceuticals, Inc. (Nasdaq: SGXP ) today,announced ... for the acquisition of SGX in an all-cash transaction. ... focused on drug,discovery and development in the area of ...
... result in 12-years of safe use. , ... St. Louis, MO (PRWEB) ... today, dietitian Mary Lee Chin describes the process of food ... In the video, Chin discusses how consumers on a daily basis make ...
... NanoBio(R) Corp., a,biopharmaceutical company focused on developing ... diseases, today announced the,appointment of Daniel B. Dubin, ... Dubin currently serves as Vice Chairman and a ... investment banking firm., "Dan,s keen understanding of ...
Cached Biology Technology:Lilly to Acquire SGX Pharmaceuticals 2Lilly to Acquire SGX Pharmaceuticals 3Lilly to Acquire SGX Pharmaceuticals 4Lilly to Acquire SGX Pharmaceuticals 5Dietitian Mary Lee Chin Comments on Proven Value and Safety of Food Biotechnology in New Online Video 2Dietitian Mary Lee Chin Comments on Proven Value and Safety of Food Biotechnology in New Online Video 3Dietitian Mary Lee Chin Comments on Proven Value and Safety of Food Biotechnology in New Online Video 4Daniel B. Dubin, M.D., Joins NanoBio Corp.'s Board of Directors 2
(Date:8/21/2014)... Nxt-ID, Inc. (OTCQB: NXTD), a biometric authentication ... today that its shares of common stock and the ... its proposed underwritten public offering of common stock and ... Capital Market, subject to closing of its proposed underwritten ... will trade under the symbol "NXTD" and "NXTDW," respectively. ...
(Date:8/21/2014)... but they are the ultimate source of all organic ... dependent on algae, too, to suck up climate-warming carbon ... bottom of the ocean. Now, by using a combination ... showing that viruses infecting those algae are driving the ... else stays essentially the same, and this has important ...
(Date:8/21/2014)... , Aug. 21, 2014 /PRNewswire-iReach/ -- LiveScan ... has agreed to a partnership with Gabriel Health ... fastest growing Certified Nursing Assistant preparatory ... Institute  an exclusive member of Binary,s LiveScan service ... Biometrics will improve its service capabilities by ...
Breaking Biology News(10 mins):Nxt-ID Approved for NASDAQ Capital Market Listing 2Nxt-ID Approved for NASDAQ Capital Market Listing 3Viruses take down massive algal blooms, with big implications for climate 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 2LiveScan Provider Binary Biometrics Announces Partnership with Preeminent CNA School, Gabriel Health Institute to Expand Services in Orlando Region 3
... , NEW YORK, NY, Nov. 18, 2013 Columbia University ... 15th Naomi Berrie Award for Outstanding Research in Diabetes, for ... fat and its role in diabetes and other metabolic diseases. ... transform the scientific concept of fat as an inert storage ...
... that power electric cars have problems. They take a ... enough to drive long distances. They don,t allow drivers ... Researchers at the University of California, Riverside,s Bourns College ... battery in an environmentally friendly way to solve some ...
... areas, and even one,s own home, limited access to ... diagnosis and treatment of disease. Many qualitative tests that ... at-home pregnancy test) have been optimized for use in ... measure the precise concentration of biomolecules, not just their ...
Cached Biology News:Columbia honors Philipp Scherer for helping to define body fat as major endocrine organ 2Columbia honors Philipp Scherer for helping to define body fat as major endocrine organ 3Columbia honors Philipp Scherer for helping to define body fat as major endocrine organ 4Pressure cooking to improve electric car batteries 2SlipChip counts molecules with chemistry and a cell phone 2SlipChip counts molecules with chemistry and a cell phone 3SlipChip counts molecules with chemistry and a cell phone 4SlipChip counts molecules with chemistry and a cell phone 5
sterile filtered, off the clot, all male donors, Total Protein: 4.5 to 8.5 g/dl...
Recombinant Mouse MMP-9, CF...
Human/Mouse/Rat JNK Pan Specific Affinity Purified PAb...
Blue Standard is 3-cyano-7-hydroxycoumarin....
Biology Products: