Navigation Links
Neurologix Presents One-Year Follow-Up Data From Phase 2 Study of NLX-P101 in Parkinson's Disease at International Neuromodulation Society 10th World Congress
Date:5/26/2011

FORT LEE, N.J., May 26, 2011 /PRNewswire/ -- Neurologix, Inc. (OTCBB: NRGX) announced the presentation today of efficacy results through one year of follow-up in patients treated as part of the Company's successful Phase 2 clinical trial for its novel, investigational gene therapy NLX-P101 for the treatment of Parkinson's disease (PD).  Improvements in the Unified Parkinson's Disease Rating Scale (UPDRS) at 12 months for the randomized, double-blind, sham surgery-controlled trial of 45 subjects with advanced PD confirmed that patients treated with NLX-P101 experienced sustained, positive, long-term benefits. The one-year follow-up data were presented by one of the scientific co-founders of Neurologix, Michael G. Kaplitt, M.D., Ph.D., at the International Neuromodulation Society's (INS) 10th World Congress in London.

In the one-year follow-up analysis, patients treated with NLX-P101 who achieved previously defined moderate-to-large clinically-meaningful symptom improvements (> / = 9 points in off-medication UPDRS motor score), increased from 50 percent at six months to 63 percent at one year. This major subgroup of NLX-P101-treated patients experienced a mean 37 percent improvement in their symptoms after one-year, with an average improvement of 14 points in off-medication UPDRS motor score. Among all patients included in the NLX-P101 treatment group, the clinical improvements demonstrated at six months were maintained, with an average 8.2 point improvement in off-medication UPDRS motor score at 12 months compared to an 8.1 point improvement at six months. No serious adverse events (SAEs) related to the gene therapy or surgical procedure were reported in either the blinded six-month study period or the completed 12 month study phase.

"These results demonstrate that treatment with NLX-P101 improved the primary motor symptoms of Parkinson's disease in patients overall, with a majority obtaining a highly clinically meaningful improvement," said
'/>"/>

SOURCE Neurologix, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related biology technology :

1. Bluestar Silicones Presents Adhesive Gels for Wound Care at Medical Grade Polymers Conference
2. Acologix Presents Preclinical Data on Cartilage Regeneration by AC-100 at the 30th ASBMR Annual Meeting
3. Enobia Pharma Presents PreClinical Data Showing ENB-0040 Significantly Improved Survival and Healed Skeletal Manifestations of Severe Hypophosphatasia in Mice
4. MedImmune Presents Data at AAP National Conference & Exhibition Demonstrating Burden of RSV Disease
5. GeoVax Presents Data at AIDS Vaccine 2008 Conference
6. Dendreon Presents Preclinical Data Validating Anti-Tumor Activity of D-3263, a Trp-p8 Agonist
7. MedImmune Presents Data Highlighting its Progressive Inflammatory Disease Portfolio at the 72nd Annual Meeting of the American College of Rheumatology
8. Northern Antibiotics Presents New Data on Novel Polymyxin Compounds at the Joint ICAAC/IDSA 2008
9. Sangamo BioSciences Presents Data at ICAAC Demonstrating In Vivo Protection Against HIV Infection by CCR5-ZFN Therapeutic
10. Prominent Urologist Dr. David B. Samadi Presents Breakthrough Robotic Surgery Techniques on OR Live Webcast
11. AmeriCares Presents Power of Partnership Award to Baxter
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... 30, 2014 LayerBio, Inc., an MIT ... its first round of seed financing from friends and ... efforts to develop a novel sustained-release product for ophthalmology. ... investors and their commitment to this important work," said ... is one of many areas in which innovations in ...
(Date:7/29/2014)... (PRWEB) July 30, 2014 “PharmaSphere: ... Equity and Venture Capital Funding” report provides in-depth ... the private equity and venture capital segments of ... are expected to have significant impact on the ... and globally. Furthermore, the report identifies regions of ...
(Date:7/29/2014)... 29, 2014 The advanced optical methods ... that are driving a revolution in the neurosciences were ... journal published by SPIE, the international society for ... with the launch of the BRAIN Initiative in the ... lay out a vision for and provide examples of ...
(Date:7/29/2014)... 29, 2014 Human Longevity, Inc. (HLI), a ... on extending the healthy, high performance human life span, ... Ph.D., an expert in machine learning and machine translation ... HLI from Google where he was Distinguished Research Scientist ... directly to HLI Co-Founder and CEO, J. Craig ...
Breaking Biology Technology:Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 2Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 3Strategic Trends of Biotech Investment Industry (Private Equity and Venture Capital Funding) in New Report Available at MarketOptimizer.org 4SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 2SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 3SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 4Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 2Franz Och, Ph.D., Expert in Machine Learning and Machine Translation, Joins Human Longevity, Inc. as Chief Data Scientist 3
... , ... a leading developer of innovative research productivity tools, announces the release of FreezerPro MultiSite, ... multiple, independent labs on a single instance of FreezerPro, facilitating IT resources, simplifying administration ... ...
... May 20 L.J. Star , ... flow indicators, announced that it has a suite of solutions for the ... , , ... to connect and visually monitor fluid flows, and thereby help maintain strict ...
... H. Chon, PhD, head of the Department of Biomedical ... Snehraj Merchant of The ScottCare Corporation, makes it possible ... of atrial fibrillation (AF), the most common form of ... algorithm, utilized in the new ScottCare CardioView Dx Suite, ...
Cached Biology Technology:RURO Launches FreezerPro MultiSite 2L.J. Star Announces Stainless Sanitary Fittings, Sight Glasses and Sight Flow Indicators for the Special Demands of the Pharmaceutical Industry 2L.J. Star Announces Stainless Sanitary Fittings, Sight Glasses and Sight Flow Indicators for the Special Demands of the Pharmaceutical Industry 3L.J. Star Announces Stainless Sanitary Fittings, Sight Glasses and Sight Flow Indicators for the Special Demands of the Pharmaceutical Industry 4Detection of potentially deadly atrial fibrillation dramatically improved by new algorithm 2Detection of potentially deadly atrial fibrillation dramatically improved by new algorithm 3
(Date:7/30/2014)... The analysis of the roughly 3,000 pieces is still ... that the results will be of major significance. "Amazingly ... insect species in Fushun amber that we found in ... , The Baltic amber comes from the Baltic ... Sites rich in finds are, e.g., the coastal regions ...
(Date:7/29/2014)... research by academics in the University of Bristol,s Nutrition ... take liquid calories into account when planning meals. , ... the Study of Ingestive Behavior Conference (SSIB 2014) in ... argues that we do. , The team was led ... School of Experimental Psychology. , As part of a ...
(Date:7/29/2014)... If you,ve ever ordered the wrong food at a restaurant, ... may have less to do with what you want and ... After analyzing 217 menus and the selections of over 300 ... International Journal of Hospitality Management showed that when it ... most: what you see on the menu and how you ...
Breaking Biology News(10 mins):Chinese mosquitos on the Baltic Sea 2Menu secrets that can make you slim by design 2
... Professor Hannes Lohi,s research group at the University of ... in ITGA10 gene, causing chondrodysplasia in two dog breeds, ... research revealed a new chondrodysplasia gene in dogs, and ... implications on bone biology as well as canine health. ...
... Huonglongbing, or citrus greening, looms darkly over the United ... whose fresh fruit alone was valued at more than ... team led by a University of California, Davis, plant ... picture of how citrus greening impacts trees before they ...
... that expecting a reward or punishment can affect brain ... sight or touch. For example, research shows that these ... are expecting a treat. However, researchers know less about ... expected reward is denied. Insight on these scenarios can ...
Cached Biology News:New dwarfism mutation identified in dogs 2New study offers hope for halting incurable citrus disease 2New study offers hope for halting incurable citrus disease 3Getting an expected award music to the brain's ears 2
CQCS kit for first KR 4i , (first unit)....
... 384, compatible with hood ... handling system for 384-well ... accurately prepares large quantities ... The Wellpro also performs ...
...
...
Biology Products: