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NeurogesX to Present at Needham Life Sciences Conference
Date:6/3/2009

r materially due to various risks and uncertainties, including, but not limited to; positive results in clinical trials may not be sufficient to obtain FDA approval; any regulatory approvals which are received may be limited to certain indications; NeurogesX' product candidates may have unexpected adverse side effects or inadequate therapeutic efficacy physician or patient reluctance to use Qutenza or NGX-1998, if approved, or the inability of physicians to obtain sufficient reimbursement for such procedures; potential alternative therapies; maintaining adequate patent or trade secret protection without violating the intellectual property rights of others; and other difficulties or delays in, clinical development, obtaining regulatory approval, market acceptance and commercialization of NeurogesX' product candidates and the advantages of NeurogesX' product candidates over other pain therapies. For further information regarding these and other risks related to NeurogesX' business, investors should consult NeurogesX' filings with the Securities and Exchange Commission.

    NeurogesX, Inc.            The Ruth Group
    Stephen Ghiglieri          Sara Pellegrino (investors)
    Chief Financial Officer    (646) 536-7002
    (650) 358-3310             spellegrino@theruthgroup.com

                               Jason Rando (media)/Janine McCargo
                               (646) 536-7025/7033
                               jrando@theruthgroup.com
                               jmccargo@theruthgroup.com


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SOURCE NeurogesX, Inc.
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