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NeurogesX Added to Russell 3000 Index
Date:6/29/2009

SAN MATEO, Calif., June 29 /PRNewswire-FirstCall/ -- NeurogesX, Inc. (Nasdaq: NGSX) announced today that it has been added to the broad-market Russell 3000(R) and small-cap Russell(R) 2000 Indexes. The addition became effective at the close of market June 26, 2009 when Russell Investments reconstituted its U.S. and global equity indexes.

Annual reconstitution of Russell's U.S. indexes captures the 4,000 largest U.S. stocks as of the end of May, ranking them by total market capitalization. Inclusion in the Russell 3000, which remains in place for one year, means automatic inclusion in the large-cap Russell 1000(R) Index or small-cap Russell 2000(R) Index as well as the appropriate growth and value style indexes. The Russell 3000 also serves as the U.S. component to the Russell Global Index, which Russell launched in 2007. Russell determines membership for its equity indexes primarily by objective, market-capitalization rankings and style attributes.

Anthony DiTonno, CEO of NeurogesX, commented, "We welcome the addition of NeurogesX to the Russell 3000 index, which is well timed with our ongoing transition into a commercial-stage biopharmaceutical company. With several upcoming milestones surrounding our lead product Qutenza(TM), including the launch in Europe and potential for a US approval, our inclusion in the index could potentially provide exposure for the Company to a broader base of institutional investors that use the indices to benchmark their portfolios.

Russell indexes are widely used by investment managers and institutional investors for index funds. An industry-leading $4 trillion in assets are currently benchmarked to them for both passive and active investment strategies.

About NeurogesX, Inc.

NeurogesX (Nasdaq: '/>"/>

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