Navigation Links
Neurochip technology developed by Canadian team
Date:8/10/2010

The University of Calgary, Faculty of Medicine scientists who proved it is possible to cultivate a network of brain cells that reconnect on a silicon chip or the brain on a microchip have been involved in the development of new technology that monitors brain cell activity at a resolution never achieved before.

Developed with the National Research Council Canada (NRC), the new silicon chips are also simpler to use, which will help future understanding of how brain cells work under normal conditions and permit drug discoveries for a variety of neurodegenerative diseases such as Alzheimer's and Parkinson's.

The new technology from the lab of Naweed Syed, PhD, in collaboration with the NRC, is published online this month in the journal, Biomedical Microdevices.

"This technical breakthrough means we can track subtle changes in brain activity at the level of ion channels and synaptic potentials, which are also the most suitable target sites for drug development in neurodegenerative diseases and neuropsychological disorders," says Syed, professor and head of the Department of Cell Biology and Anatomy, member of the Hotchkiss Brain Institute and advisor to the Vice President Research on Biomedical Engineering Initiative of the University of Calgary.

The new neurochips are also automated. Previously it took years of training to learn how to record ion channel activity from brain cells, and it was only possible to monitor one or two cells simultaneously. Now, larger networks of cells can be placed on a chip and observed in minute detail, allowing the analysis of several brain cells networking and performing automatic, large-scale drug screening for various brain dysfunctions.

"The success of this project was achieved by reaching across the boundaries of scientific disciplines," said Dr. Roman Szumski, NRC Vice President, Life Sciences. "This is a true partnership of neuroscientists, engineers and physicists from different Canadian R&D institutions. We are committed both to understanding the ultimate mystery of the brain and to developing tools and systems to accelerate development of better diagnostics and therapeutics for brain diseases."

This new technology has the potential to help scientists in a variety of fields and on a variety of research projects. Gerald Zamponi, PhD, professor and head of the Department of Physiology and Pharmacology, and member of the Hotchkiss Brain Institute at the University of Calgary, says, "This technology can likely be scaled up such that it will become a novel tool for medium throughput drug screening, in addition to its usefulness for basic biomedical research".


'/>"/>

Contact: Marta Cyperling
mcyperli@ucalgary.ca
403-210-3835
University of Calgary
Source:Eurekalert

Related biology technology :

1. VIASPACE CEO Discusses Giant King Grass at Industrial Biotechnology Congress in China
2. Microbix Signs $2 Million Partnership Agreement For its Livestock Semen Sexing Technology (LumiSort(TM))
3. David Blumenthal, HHS National Coordinator for Health Information Technology, to Speak at Lucian Leape Institute Third Annual Forum & Gala on Sept. 16
4. Beike Biotechnology Opens First Chinese Rehabilitation Center in Romania
5. Ocean Nutrition Canada Announces Acquisition of Exclusive License to GAT Food Essentials, Omega-3 Microencapsulation-Emulsion Technology
6. MRC Technology Enters Into an Exclusive License Agreement With Genentech
7. National Nanotechnology Initiatives strategic planning stakeholder workshop
8. Building Biotech Technology Transfer Opportunities: Sponsor and Developer Strategies for Success
9. ‘Next Big Idea' Fest Aims to Spark Interest Among NM Youth in Science, Technology as Future Career Path
10. Medical Simulation Corporation Partners with Hutchinson Technology in Training of Healthcare Professionals on Noninvasive Tissue Oxygenation Monitoring
11. New Report Finds A Brain Health Revolution in the Making, Driven by Digital Technology and Neuroplasticity Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... Early-career researchers from Indonesia , ... Uganda and Yemen honored ... Indonesia , Nepal , ... are being honored for their accomplishments in nutrition, psychiatry, biotechnology, ... young women scientists who are pursuing careers in agriculture, biology and medicine ...
(Date:2/10/2016)... is introducing a hybrid membership model which will provide ... joining or renewing through an organizational purchasing model. For ... employee in any size association or AMC office can ... benefits.   John H. Graham, IV , ... organizations of any size and their employees to gain ...
(Date:2/10/2016)... Feb. 10, 2016  Allergan plc (NYSE: AGN ... Brent Saunders , Allergan,s CEO and President, will ... chat session at the RBC Capital Markets Healthcare Conference ... at The New York Palace Hotel in ... webcast live and can be accessed on Allergan,s Investor ...
(Date:2/10/2016)... ... 10, 2016 , ... HOLLOWAY AMERICA, a leading custom stainless ... Mountain Chapter 21st Annual Vendor Exhibition on Thursday, February 18, 2016. The Rocky ... its annual event, which will run from 3:00 p.m. - 8:30 p.m. at ...
Breaking Biology Technology:
(Date:1/25/2016)... Jan. 25, 2016  Glencoe Software, the world-leading supplier ... publication industries, will provide the data management solution OMERO ... Photo ... Phenotypic analysis measures the characteristics ... allowing comparisons between states such as health and disease, ...
(Date:1/21/2016)... 21, 2016 --> ... market research report "Emotion Detection and Recognition Market by Technology ... (Facial Expression, Voice Recognition and Others), Services, Application ... to 2020", published by MarketsandMarkets, the global Emotion ... USD 22.65 Billion by 2020, at a CAGR ...
(Date:1/20/2016)... JOSE, Calif. , Jan. 20, 2016 /PRNewswire/ ... developer of human interface solutions, today announced sampling ... controller solution for wearables and small screen applications ... such as printers. Supporting round and rectangular shapes, ... S1423 offers excellent performance with moisture on screen, ...
Breaking Biology News(10 mins):