Navigation Links
NeuroDerm Announces Enrollment in a Phase 2 Study of ND0612, a Continuous Levodopa/Carbidopa Drug for the Treatment of Parkinson's Disease
Date:4/15/2013

NESS ZIONA, Israel, April 15, 2013 /PRNewswire/ --

NeuroDerm, Ltd. announced today that enrollment of patients is ongoing in its Phase IIa clinical trial of ND0612, a novel drug formulation for the treatment of Parkinson's disease. ND0612 is a proprietary levodopa/carbidopa liquid formula under development for continuous sub-cutaneous administration through a patch pump.  It is designed to provide steady levodopa blood levels in Parkinson's disease.

In previous phase I studies, ND0612 was shown to be safe and tolerable and reached steady state, clinically meaningful levodopa concentrations for the first time in man.  Furthermore, steady state levodopa concentrations were maintained in a practical manner during both day and night. The current Phase II double-blind, randomized placebo controlled study in Parkinson's disease patients will assess ND0612 for safety and tolerability as well as for levodopa and carbidopa steady state plasma levels.

"Following its success in phase I trials, ND0612 is now entering trials in patients. An important objective of this study will be to find out what steady state levodopa concentrations can be reached in patients. In healthy volunteers, ND0612 reached day and night steady state levodopa levels, the elusive holy grail of Parkinson's levodopa therapy, in a conveniently administered drug that should be available to all PD patients. Moreover, ND0612 bypasses the gastrointestinal tract and should be little influenced by intestinal absorption or oral ingestion of food or drugs. This trial marks a landmark in the development of ND0612, a novel levodopa drug that could become a breakthrough treatment option in Parkinson's Diseases."

About Parkinson's Disease

Parkinson's disease affects approximately 6M patients in the world. It is caused by decreasing dopamine signaling in the brain as dopaminergic brain cells die off. Levodopa is the "Gold
'/>"/>

SOURCE NeuroDerm Ltd
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. Veracyte Announces Appointment of Shelly D. Guyer as Chief Financial Officer
2. Probiotic Action Announces New Insight on Why Acne is a Problem for First World Citizens and Offers Advice on Treatments
3. Vestiage Announces Key Partners for Launch of Monterey Bay Nutraceuticals Anti-Aging Wellness Products
4. Probiotic Action Announces A New Natural Alternative to Expensive and harmful Acne Treatments
5. Rigaku Announces New EDXRF Method for Elemental Analysis in Gold Processing
6. ?The MedZilla.com Employment Report for April, 2013: Unemployment Rate Drops as Obama Announces Major Bio-Tech Research Initiative
7. Sangamo BioSciences Announces Presentation At Regen Med Investor Day
8. Vestiage Announces Filing of Disclosure Statement with Exchange
9. ChanTest Announces Their Second User Meeting: Partnerships in Drug Discovery
10. BioRestorative Therapies Announces Chairman of Its Scientific Advisory Board to Speak at Vatican
11. Probiotic Action Announces New Edible Probiotic Trend
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2015)... , May 28, 2015 RXi Pharmaceuticals ... on discovering and developing innovative therapeutics, primarily in the ... of a public offering of 26 million units at ... for gross proceeds of approximately $10.4 million. Each unit ... a 13-month overallotment purchase right to purchase 0.50 of ...
(Date:5/28/2015)... -- GenVec, Inc. (Nasdaq: GNVC ) today announced that ... will present a company overview at the Jefferies 2015 ... June 4, 2015. The live and ... at the following link:  http://wsw.com/webcast/jeff88/gnvc .  This link ... visit www.genvec.com , click on "Investors and Media" ...
(Date:5/28/2015)... (PRWEB) May 28, 2015 The Fertility ... our own Dr. Danielle Vitiello has taken on a ... role, Dr. Vitiello will provide guidance, leadership, oversight and ... to count Dr. Vitiello among our team of experienced ... and CEO, Joseph A. Hill, M.D. “Her expertise and ...
(Date:5/28/2015)... May 28, 2015 Whitehouse Laboratories is ... its long term partnership with PTI Inspection Systems. Whitehouse ... provide clients with custom-tailored method development and validation ... currently available. The agreement includes a more formal program ... across organizational lines. This enables a more effective team ...
Breaking Biology Technology:RXi Pharmaceuticals Announces $10 Million Public Offering of Common Stock and Warrants 2RXi Pharmaceuticals Announces $10 Million Public Offering of Common Stock and Warrants 3GenVec To Present At The Jefferies Healthcare Conference 2Danielle Vitiello, MD of Fertility Centers of New England, Named New Medical Director 2Whitehouse Labs Renews & Enhances Partnership with PTI Inspection Systems 2Whitehouse Labs Renews & Enhances Partnership with PTI Inspection Systems 3
... Interleukin Genetics,Inc. (AMEX: ILI ), announced today ... Wednesday, May 14, 2008 at 4:30 p.m. ET to ... an update on recent,corporate developments., To access the ... webcast will be available on the Investors,section of the ...
... Patent Encompassing Tobramycin Inhalation Powder and Other ... Aminoglycoside Antibiotics Issued to Nektar, SAN ... ) today announced that the U.S. Patent and Trademark ... methods for,creating and delivering Tobramycin Inhalation Powder (TIP) and ...
... Dermagraft presence within government channels, WEST ... Advanced,BioHealing, Inc. (ABH) and Regenesis Biomedical, ... promotion of Dermagraft(R) within the United,States (US) ... agreement,Regenesis will provide its specialized sales force ...
Cached Biology Technology:Interleukin Genetics Announces Conference Call and Webcast to Discuss First Quarter 2008 Business Results 2Nektar Receives Patent Covering Pulmonary Targeted Antibiotics 2Nektar Receives Patent Covering Pulmonary Targeted Antibiotics 3Advanced BioHealing and Regenesis Biomedical Form Co-Promotion Alliance for Dermagraft(R) 2Advanced BioHealing and Regenesis Biomedical Form Co-Promotion Alliance for Dermagraft(R) 3
(Date:4/27/2015)... 2015  For more than four decades, AUVSI,s ... the premier worldwide event for the unmanned land, sea, ... event for any local, national, or trade news organization ... markets and current applications of unmanned technologies. The conference ... $48 billion industry, and how it will soon impact ...
(Date:4/21/2015)... 2015 High crime rate, ... boosting access control systems market in Saudi ... recently published report by TechSci Research " Saudi Arabia Access ... control systems market in Saudi Arabia ... access control systems market in the Kingdom is growing ...
(Date:4/17/2015)... 2015 Increasing adoption ... advancement to drive biometric systems market in ... According to a recently released TechSci ... ", biometric systems market in Saudi ... at CAGR of over 22% through 2020. The ...
Breaking Biology News(10 mins):UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 2Saudi Arabia Access Control Systems Market to Touch USD1.2 Billion by 2020 Says TechSci Research 3Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 2Saudi Arabia Biometric Systems Market to Grow at 22% Through 2020, Says TechSci Research 3
... at borders. Mexico, the U.S., and Canada share the ... problems. In an effort to promote active communication among ... and the Institute of Geology of the National Autonomous ... are hosting the 108th meeting of GSA,s Cordilleran Section ...
... includes a USC scientist has methodically demonstrated that a face,s ... are the key to recognizing a person. Their ... faces "holistically," appears this month in Psychological Science . ... brain functions, these results may help scientists understand rare facial ...
... describes how bacteria use a previously unknown means to defeat ... a common "housekeeping" enzyme in a way that enables the ... appears in the Proceedings of the National Academy ... warfare with one another, and many antibiotics used in medicine ...
Cached Biology News:Geological Society of America Cordilleran section meets in the heart of Mexico 2Geological Society of America Cordilleran section meets in the heart of Mexico 3Geological Society of America Cordilleran section meets in the heart of Mexico 4New research about facial recognition turns common wisdom on its head 2Team discovers how bacteria resist a 'Trojan horse' antibiotic 2
... venom Description: Phosphodiesterase I (venom ... studying nucleic acid structure and ... 5'-mononucleotides from 3'-hydroxy-terminated ribo-oligonucleotides and ... cleaves ADP-ribosylated proteins at the ...
... IITC Life Science Rotarods are used to assess ... or fatigue resistance on mice and rats using ... Extremely user friendly; the animals are placed on ... drops onto the individual sensing platforms below, its ...
... DNase I Amplification Grade ... DNA to oligodeoxyribonucleotides. The ... units/mg. DNAse I Amplification ... and tested for absence ...
... DNase I, ds Qualified is a special ... be used for double stranded cleavage of DNA ... of Mg2+, the enzyme makes double strand breaks ... of the resulting fragments can be controlled by ...
Biology Products: