Navigation Links
Neuralstem Cells Induce Significant Functional Improvement In Permanent Rat Spinal Cord Injury, Cell Study Reports
Date:9/13/2012

t our neural stem cells can induce regeneration of injured spinal cord axons into the graft and serve as a bridge to reconnect to gray matter motor neurons for many spinal cord segments below the injury," said Karl Johe, PhD, Chairman of Neuralstem's Board of Directors and Chief Scientific Officer. "This is important in spinal cord injury because the nerve connections below the point of injury die, causing paralysis. Our cells built a bridge that received inputs from regenerating rat axons above the injury.  They also sent out new human axons which made new synaptic connections with the host motor neurons in the gray matter below the injury. The fact that these cells induce regeneration of axons and partial recovery of motor function makes them relevant for testing for the treatment of human spinal cord injury."

About the Study

In a study of 12 rats, all 12 underwent complete spinal transections at vertebrae, T3. Six of these were subsequently transplanted with Neuralstem spinal cord stem cells (NSI-566) seven days after the injury. This group was assessed over the next seven weeks and compared to the control group, which had not received transplants. The transplanted rats exhibited significant locomotor recovery, regaining movement in all lower extremity joints. A majority of the grafted cells (57%) turned into neurons. From these, the study reported, a remarkable number of axons emerged, extending both above and below the point of spinal cord lesion. These axons expressed synaptic proteins in the host gray matter, which suggests they made synaptic contact with the host spinal neurons.

About Neuralstem

Neuralstem's patented technology enables the ability to produce neural stem cells of the human brain and spinal cord in commercial quantities, and the ability to control the differentiation of these cells constitutively into mature, physiologically relevant human neurons and glia. Neuralstem has recently completed an FD
'/>"/>

SOURCE Neuralstem, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Neuralstem President And CEO To Present At The 2012 Rodman & Renshaw Annual Healthcare Conference
2. Neuralstem Receives Notice Of Issuance For Patent Covering Human Neural Cell Transplantation For Neurodegenerative Conditions
3. Neuralstem CEO to Present at the World Stem Cells and Regenerative Medicine Congress in London
4. Fourteenth Patient Dosed in Neuralstem ALS Stem Cell Trial
5. Neuralstem Announces Closing of $5.2-Million Registered Direct Offering
6. Neuralstem President and CEO to Present at BIO CEO & Investor Conference 2012
7. Neuralstem President and CEO to Update Ongoing ALS and NSI-189/Major Depressive Disorder Trials at 2012 Biotech Showcase
8. Neuralstem ALS Stem Cell Trial Featured on Fox Atlanta
9. AllCells Introduces Autoimmune Diseased Cells and Tissue Products
10. Stem Cells Bring New Hope for Parry-Romberg Syndrome Patients
11. AllCells, LLC Named to Inc. Magazines 500/5000 List of Fastest Growing Companies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... 2014 With the accelerated aging ... health expenditure as well as the improved medical ... diagnostic reagent industry has been developing quickly, especially ... 2013, Chinese in vitro diagnostics market size reached ... in vitro diagnostic reagents. , Read complete ...
(Date:7/30/2014)... (PRWEB) July 30, 2014 BCC Research ... Global Markets for Enzymes in Industrial Applications , the ... to nearly $7.1 billion by 2018, registering a five-year ... is estimated to be recorded in the detergent enzyme ... period. , Enzyme technology has influenced almost every sector ...
(Date:7/30/2014)... AZ (PRWEB) July 30, 2014 ... State-of-the-art facility and complementary therapies brings comprehensive cancer ... foot, state-of-the-art Yuma Regional Cancer Center has officially ... 2012, the program includes services such as open, ... massage therapy, American Cancer Society Resource Center, hematology, ...
(Date:7/30/2014)... , July 30, 2014  Dyadic International, ... company whose patented and proprietary technologies are used ... other proteins for the bioenergy, bio-based chemical, biopharmaceutical ... of Thomas "Tom" Dubinski as Vice President and ... leading the financial and information technology operations for ...
Breaking Biology Technology:China Diagnostic Reagent Industry Report, 2013-2016 | Researchmoz 2China Diagnostic Reagent Industry Report, 2013-2016 | Researchmoz 3Global Market for Industrial Enzymes to Reach Nearly $7.1 Billion by 2018; Detergent Enzyme Market to Record Maximum Growth 2Global Market for Industrial Enzymes to Reach Nearly $7.1 Billion by 2018; Detergent Enzyme Market to Record Maximum Growth 3Sate-of-the-Art Yuma Regional Cancer Center Officially Opens 2Thomas Dubinski joins Dyadic as Chief Financial Officer 2Thomas Dubinski joins Dyadic as Chief Financial Officer 3Thomas Dubinski joins Dyadic as Chief Financial Officer 4
... Street Healthcare Partners , a strategic private equity firm ... Garrett has joined the firm as an operating partner. ... executive officer of Beckman Coulter, Inc., brings to Water ... care businesses ranging from diagnostics and life sciences to ...
... Fresh®, Inc., maker of the popular FireFly® children,s light-up ... raise awareness and funds for Smile Train, the world,s ... will donate $1 for every new "Like" on ... Train.  The organization provides life-changing surgery for poor children ...
... Gilliam, a famed Hollywood actor and former Golden Gloves ... line of nutritional products. Bubba, who once worked with ... Eastwood, Gene Wilder, Andy Griffith, Jeff Bridges, Hilary Swank, ... Fox, Willie Nelson and more, says, "I,ve never slept ...
Cached Biology Technology:Scott Garrett Joins Water Street Healthcare Partners 2Scott Garrett Joins Water Street Healthcare Partners 3FireFly® Toothbrush Facebook Campaign Raises Funds for Smile Train 2Terra Biotech Goes Hollywood with New Endorsement Burton 'Bubba' Gilliam 2
(Date:7/30/2014)... In a paper published online today in the journal ... Northeastern researchers Evan Kodra and Auroop Ganguly found that ... the variability in temperature extremes. For instance, while each ... those averages will also tend to fall within a ... than are currently being observed. This means that even ...
(Date:7/29/2014)... warms and sea ice retreats, the North is changing. ... open water which is predicted to extend across the ... Storms thus have the potential to create Arctic swell ... unpredictable element to the region. , A University of Washington ... middle of the Arctic Ocean, and detected house-sized waves ...
(Date:7/29/2014)... Research and Markets  has announced the ... Market 2014-2018" report to their offering. ... term BI refers to applications and technologies that are ... about a company,s operations. BI help organizations to acquire ... example, metrics on sales, production, and internal operations. ...
Breaking Biology News(10 mins):Big data confirms climate extremes are here to stay 2Huge waves measured for first time in Arctic Ocean 2Huge waves measured for first time in Arctic Ocean 3Global SaaS-based Business Intelligence (BI) Market 2014-2018 2
... turmeric packs more than just flavor it shows ... Curcumin, found in turmeric, stopped the potentially ... cells, says Aarthi Narayanan, lead investigator on the new ... Center for Biodefense and Infectious Diseases. Mosquito-borne Rift ...
... COLUMBUS, Ohio - Almost 41 percent of Ohioans have visited ... the past year, and of those, nearly one-half usually spend ... findings in a new report. These figures and other ... lakes and rivers, and particularly Lake Erie, as natural resources, ...
... tale of your family line. It carries the genetic history ... Tel Aviv University researcher, it,s also possible to use it ... Halperin of TAU,s Blavatnik School of Computer Science and Department ... researchers from University of California, Los Angeles, are giving new ...
Cached Biology News:Turmeric spices up virus study 2Turmeric spices up virus study 3Ohioans love their lakes, but are concerned for their future 2Ohioans love their lakes, but are concerned for their future 3Ohioans love their lakes, but are concerned for their future 4A GPS in your DNA 2
...
Antibodies were affinity purified using epitopes specific to QKI immobilized on solid support....
Acrylamide, 500 g. Assay: > 99.9%, acrylic acid: < 0.001%. Conductivity (35%): < 2 umhos/cm.Risks: 45, 46, 48, 23, 24, 25 ; Safety Precautions: 53, 44. Category: Nucleotides & Enzymes & Biochemicals...
Assay Diluent Trial Pack, 4 x 100 mL...
Biology Products: