Navigation Links
Neuralstem Cells Induce Significant Functional Improvement In Permanent Rat Spinal Cord Injury, Cell Study Reports
Date:9/13/2012

t our neural stem cells can induce regeneration of injured spinal cord axons into the graft and serve as a bridge to reconnect to gray matter motor neurons for many spinal cord segments below the injury," said Karl Johe, PhD, Chairman of Neuralstem's Board of Directors and Chief Scientific Officer. "This is important in spinal cord injury because the nerve connections below the point of injury die, causing paralysis. Our cells built a bridge that received inputs from regenerating rat axons above the injury.  They also sent out new human axons which made new synaptic connections with the host motor neurons in the gray matter below the injury. The fact that these cells induce regeneration of axons and partial recovery of motor function makes them relevant for testing for the treatment of human spinal cord injury."

About the Study

In a study of 12 rats, all 12 underwent complete spinal transections at vertebrae, T3. Six of these were subsequently transplanted with Neuralstem spinal cord stem cells (NSI-566) seven days after the injury. This group was assessed over the next seven weeks and compared to the control group, which had not received transplants. The transplanted rats exhibited significant locomotor recovery, regaining movement in all lower extremity joints. A majority of the grafted cells (57%) turned into neurons. From these, the study reported, a remarkable number of axons emerged, extending both above and below the point of spinal cord lesion. These axons expressed synaptic proteins in the host gray matter, which suggests they made synaptic contact with the host spinal neurons.

About Neuralstem

Neuralstem's patented technology enables the ability to produce neural stem cells of the human brain and spinal cord in commercial quantities, and the ability to control the differentiation of these cells constitutively into mature, physiologically relevant human neurons and glia. Neuralstem has recently completed an FD
'/>"/>

SOURCE Neuralstem, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Neuralstem President And CEO To Present At The 2012 Rodman & Renshaw Annual Healthcare Conference
2. Neuralstem Receives Notice Of Issuance For Patent Covering Human Neural Cell Transplantation For Neurodegenerative Conditions
3. Neuralstem CEO to Present at the World Stem Cells and Regenerative Medicine Congress in London
4. Fourteenth Patient Dosed in Neuralstem ALS Stem Cell Trial
5. Neuralstem Announces Closing of $5.2-Million Registered Direct Offering
6. Neuralstem President and CEO to Present at BIO CEO & Investor Conference 2012
7. Neuralstem President and CEO to Update Ongoing ALS and NSI-189/Major Depressive Disorder Trials at 2012 Biotech Showcase
8. Neuralstem ALS Stem Cell Trial Featured on Fox Atlanta
9. AllCells Introduces Autoimmune Diseased Cells and Tissue Products
10. Stem Cells Bring New Hope for Parry-Romberg Syndrome Patients
11. AllCells, LLC Named to Inc. Magazines 500/5000 List of Fastest Growing Companies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... 22, 2014  United Therapeutics Corporation (NASDAQ: ... release its second quarter 2014 financial results before ... United Therapeutics will host a half-hour teleconference ... Eastern Time.  The teleconference is accessible by dialing ... of the teleconference will be available for one ...
(Date:7/22/2014)... (PRWEB) July 22, 2014 Biofeedback ... hyperactivity disorder (ADHD) is diagnosed, selecting medication to best ... error. Analyzing brain patterns by using electroencephalography (EEG) can ... and thus lower the risk of adverse drug events. ... and Biomarkers” in the current issue of the ...
(Date:7/21/2014)... Lawrence Livermore National Laboratory ... Las Positas College (LPC) recently established a 24-month ... training for veterans, officials recently announced. , The ... is designed to help veterans develop the ... and establishes a pipeline of qualified candidates for ...
(Date:7/21/2014)... of Arts and Sciences has received a major ... , Mathew M. Maye, associate professor of chemistry, ... the National Science Foundation (NSF). The award supports ... the results of which may impact gas storage, ... , Maye,s approach is novel, in that he ...
Breaking Biology Technology:Analyzing Brain Patterns with EEG Can Help Predict Effective Use of Medication 2Analyzing Brain Patterns with EEG Can Help Predict Effective Use of Medication 3Engineering Program Established for Veterans 2Engineering Program Established for Veterans 3Syracuse University chemist to use NSF grant to study materials chemistry, nanoscience 2
... 2011 BSI Group America Inc., a leading ... announces the launch of Specialized Regulatory Training courses ... on-site, these Specialized Regulatory Courses reflect requirements of ... enabling attendees to comply efficiently with regulations in ...
... CRAWLEY, England, April 27, 2011 As image guided ... continues working to decrease treatment session times through automated ... are the first in the world to use a ... The software quickly and automatically pinpoints the position of ...
... (NASDAQ: LIFE ) today announced results for its ... first quarter was $897 million, an increase of 1 percent ... 2010. Organic revenue growth for the quarter was flat compared ... of difficult year over year comparables and the extraordinary events ...
Cached Biology Technology:BSI Group America Inc. Announces Specialized Regulatory Training Courses for the Healthcare Industry 2BSI Group America Inc. Announces Specialized Regulatory Training Courses for the Healthcare Industry 3BSI Group America Inc. Announces Specialized Regulatory Training Courses for the Healthcare Industry 4Automation Shaving More Time Off of Radiation Therapy for Patients With Cancer 2Automation Shaving More Time Off of Radiation Therapy for Patients With Cancer 3Life Technologies Announces First Quarter 2011 Results 2Life Technologies Announces First Quarter 2011 Results 3Life Technologies Announces First Quarter 2011 Results 4Life Technologies Announces First Quarter 2011 Results 5Life Technologies Announces First Quarter 2011 Results 6Life Technologies Announces First Quarter 2011 Results 7Life Technologies Announces First Quarter 2011 Results 8Life Technologies Announces First Quarter 2011 Results 9Life Technologies Announces First Quarter 2011 Results 10Life Technologies Announces First Quarter 2011 Results 11Life Technologies Announces First Quarter 2011 Results 12
(Date:7/21/2014)... Millar , a professor of entomology and ... at the University of California, Riverside, has been ... International Society of Chemical Ecology ( ISCE ). , ... is the society,s highest honor. It is awarded ... chemical ecology, the study of chemicals that mediate interactions ...
(Date:7/21/2014)... using sophisticated GPS tracking to monitor seals, every movement, ... individuals are repeatedly drawn to offshore wind farms and ... and attractive hunting grounds, according to a study published ... on July 21. , "I was shocked when ... seal track around Sheringham Shoal," an offshore wind farm ...
(Date:7/21/2014)... the James E. Wyche III Endowed Professor in ... as an invited speaker at the International Bioprinting ... Development Center in Singapore. , DeCoster, who is ... Institute for Micromanufacturing, will present a lecture titled, ... tissue models." The presentation will focus on ...
Breaking Biology News(10 mins):UC Riverside entomologist receives international honor for chemical ecology contributions 2Seals forage at offshore wind farms 2Louisiana Tech University professor presents at International Bioprinting Congress 2
... A multi-institutional consortium led by The Scripps Research Institute scientists, ... focus of a special issue of the journal Acta Crystallographica ... of the monthly journal, which publishes peer-reviewed crystallography and structural ... works of a single scientific center. The issue ...
... led by Dr Stuart Painter of the National Oceanography ... off the southeast coast of South America during the ... Patagonian Shelf marine ecosystem, which includes a globally important ... phytoplankton community. They are abundant in the sunlit upper ...
... Scientists at The University of Nottingham and the Wellcome ... switches that control the three key stages in the life ... a third of these switches can be disrupted in some ... Trust and the Medical Research Council (MRC) is a significant ...
Cached Biology News:Entire issue of scientific journal devoted to center headed by Scripps Research Scientists 2Entire issue of scientific journal devoted to center headed by Scripps Research Scientists 3Entire issue of scientific journal devoted to center headed by Scripps Research Scientists 4Entire issue of scientific journal devoted to center headed by Scripps Research Scientists 5Coccolithophore blooms in the southwest Atlantic 2Malaria research begins to bite 2Malaria research begins to bite 3
Form: Ready to use Applications: ELISA...
Form: Ready to use Applications: ELISA...
ANTI S. GROUP AG:H...
Recorder REC-111 single-channel, 1. Category: Chromatography Systems & Accessories, Systems....
Biology Products: