Navigation Links
Neural prosthesis restores behavior after brain injury
Date:12/9/2013

anted in the two brain regions.

The device amplifies signals, which are called neural action potentials and produced by the neurons in the anterior of the brain. An algorithm separates these signals, recorded as brain spike activity, from noise and other artifacts. With each spike detected, the microchip sends a pulse of electric current to stimulate neurons in the posterior part of the brain, artificially connecting the two brain regions.

Two weeks after the prosthesis had been implanted and run continuously, the rat models using the full closed-loop system had recovered nearly all function lost due to injury, successfully retrieving a food pellet close to 70 percent of the time, or as well as normal, uninjured rats. Rat models that received random stimuli from the device retrieved less than half the pellets and those that received no stimuli retrieved about a quarter of them.

"A question still to be answered is must the implant be left in place for life?" Mohseni said. "Or can it be removed after two months or six months, if and when new connections have been formed in the brain?"

Brain studies have shown that, during periods of growth, neurons that regularly communicate with each other develop and solidify connections.

Mohseni and Nudo said they need more systematic studies to determine what happens in the brain that leads to restoration of function. They also want to determine if there is an optimal time window after injury in which they must implant the device in order to restore function.


'/>"/>

Contact: Kevin Mayhood
kevin.mayhood@case.edu
216-368-4442
Case Western Reserve University
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Neuralstem ALS Stem Cell Trial Featured on Fox Atlanta
2. Neuralstem President and CEO to Update Ongoing ALS and NSI-189/Major Depressive Disorder Trials at 2012 Biotech Showcase
3. Neuralstem President and CEO to Present at BIO CEO & Investor Conference 2012
4. Neuralstem Announces Closing of $5.2-Million Registered Direct Offering
5. Fourteenth Patient Dosed in Neuralstem ALS Stem Cell Trial
6. Neuralstem CEO to Present at the World Stem Cells and Regenerative Medicine Congress in London
7. Triangles guide the way for live neural circuits in a dish
8. PhoenixSongs Biologicals, Inc. Announces Enhanced Neural Lineage-specific Cell Culture Media Products Release
9. Neuralstem Receives Notice Of Issuance For Patent Covering Human Neural Cell Transplantation For Neurodegenerative Conditions
10. Neuralstem President And CEO To Present At The 2012 Rodman & Renshaw Annual Healthcare Conference
11. Neuralstem Cells Induce Significant Functional Improvement In Permanent Rat Spinal Cord Injury, Cell Study Reports
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... PETERSBURG, Russia , July 10, 2014 ... Russian Federation Dmitry Medvedev , presented ... biopharmaceutical company BIOCAD . The Company is developing ... scope of MabNext project BIOCAD develops a number of ... cancer and autoimmune diseases. The ceremony took place at ...
(Date:7/10/2014)... D.C., April 15, 2014 -- According to the ... to nuclear security comes from terrorists acquiring sufficient ... to construct a crude nuclear explosive device. The ... nuclear trafficking have involved gram-level quantities, which can ... , According to a new study appearing this ...
(Date:7/10/2014)... Hall effect in bilayer graphene and shown that this ... electric field. , The fractional quantum Hall effect, ... are exposed to large magnetic fields, is a striking ... behave as a single system. However, while the basic ... of this collective behavior remain not well understood, in ...
(Date:7/10/2014)... new alliance will see the two universities and NPL ... with business and industry and their complementary academic strengths., ... help to shape the scientific priorities of the UK. ... up to 300 high-calibre PhD students, will provide a ... NPL, the potential of the Laboratory will be grown ...
Breaking Biology Technology:Dmitry Medvedev Presented BIOCAD the First National "Industry" Award 2Sensitive detection method may help impede illicit nuclear trafficking 2Columbia researchers observe tunable quantum behavior in bilayer graphene 2Columbia researchers observe tunable quantum behavior in bilayer graphene 3Universities of Surrey and Strathclyde selected as strategic partners in the future operation of the National Physical Laboratory 2Universities of Surrey and Strathclyde selected as strategic partners in the future operation of the National Physical Laboratory 3
... CEPH ) will hold a public memorial service to ... CEO on February 1, 2011, at 6:00 p.m. at The Franklin ... Dr. Baldino founded Cephalon in 1987 and led the company ... biotechnology companies in the world. He was a recognized pioneer in ...
... 24, 2011 Myriant Technologies, Inc. (Myriant), ... renewable bio-based chemicals, announced today the closing ... from PTT Chemical Group (PTT Chemical), Thailand,s ... http://photos.prnewswire.com/prnh/20091021/NE96331LOGO) Myriant will utilize the ...
... 2011 Cardium Therapeutics (NYSE Amex: CXM ... on December 2, 2010 has been accepted by the ... ) As previously reported, a communication from ... that the company was considered to be noncompliant with ...
Cached Biology Technology:Cephalon to Hold Public Memorial Service to Celebrate the Life of Company Founder, Frank Baldino, Jr., Ph.D. 2Myriant Technologies, Inc. Announces US$60 Million Strategic Equity Investment From PTT Chemical Group 2Myriant Technologies, Inc. Announces US$60 Million Strategic Equity Investment From PTT Chemical Group 3Cardium's Exchange Listing Compliance Plan Accepted by NYSE Amex 2Cardium's Exchange Listing Compliance Plan Accepted by NYSE Amex 3Cardium's Exchange Listing Compliance Plan Accepted by NYSE Amex 4
(Date:7/11/2014)... 1 can inhibit voltage-gated calcium channel, decrease ... However, some scholars demonstrated that cannabinoid receptor ... and increase neurotransmitter release. Dr. Yi Zhang ... Tongji Medical College, Huazhong University of Science ... and calcium imaging in cultured trigeminal ganglion ...
(Date:7/11/2014)... brains of all vertebrates, information is transmitted through ... chemical signal to be passed from one brain ... most abundant type of synapse, can be either ... learning, memory, perception and cognition, and the balance ... function. For instance, every time we learn ...
(Date:7/10/2014)... June 27, 2014  Pomerantz LLP has filed ... ("Provectus" or the "Company")(NYSE-MKT: PVCT) and certain of ... States District Court, Middle District of ... of a class consisting of all persons or ... between December 17, 2013 and May 22, 2014, ...
Breaking Biology News(10 mins):Blame it on the astrocytes 2SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT 2SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT 3
... San Diego Supercomputer Center (SDSC) at the University ... researchers worldwide unravel the enigmas of phylogenetics, the ... on the planet. The CIPRES Science Gateway ... created by SDSC researchers, allows these studies to ...
... that comes the threat of West Nile virus. Tom Hobman, ... in the Faculty of Medicine & Dentistry, is making every ... , West Nile virus infections often result in flu-like ... show no symptoms at all. But a significant percentage of ...
... new fossil find from the chalk beds of the Franconian ... predatory dinosaur reveals clear traces of fluffy plumage. It also ... The fossil of the fledgling saurian, probably newly hatched ... First of all, juveniles are extremely rare in the dinosaur ...
Cached Biology News:SDSC's CIPRES Science Gateway clarifies branches in evolution's 'tree of life' 2SDSC's CIPRES Science Gateway clarifies branches in evolution's 'tree of life' 3Researchers moving towards ending threat of West Nile virus 2Feathered saurians -- downy dinosaur discovered 2
... it uses a deep-UV deuterium bulb, which provides ... a shutter (controlled via a TTL signal or ... produces a powerful, stable output from 215-400 nm. ... are available, providing a wavelength range of 190-400 ...
... situ detection of apoptosis and mitochondrial membrane ... an early indication of the initiation of ... as a collapse in the electrochemical gradient ... the change in the membrane potential (YD). ...
... The NOVOstar is an exciting product ... Previously, cell-based assays required the use of ... accessibility for scientists in the assay development ... necessary for cell-based assays as well as ...
... One can operate as a Voltage Clamp, as ... Clamp in electrophysiology research applications. Performance in any ... equipment. • This amazing ... in the capabilities of Digital Signal Processing (DSP) ...
Biology Products: