Navigation Links
Neural implant recovers ability to make decisions
Date:9/13/2012

Researchers have taken a key step towards recovering specific brain functions in sufferers of brain disease and injuries by successfully restoring the decision-making processes in monkeys.

By placing a neural device onto the front part of the monkeys' brains, the researchers, from Wake Forest Baptist Medical Centre, University of Kentucky and University of Southern California, were able to recover, and even improve, the monkeys' ability to make decisions when their normal cognitive functioning was disrupted.

The study, which has been published today, 14 September, in IOP Publishing's Journal of Neural Engineering, involved the use of a neural prosthesis, which consisted of an array of electrodes measuring the signals from neurons in the brain to calculate how the monkeys' ability to perform a memory task could be restored.

In the delayed match-to-sample task an image was flashed onto a screen and, after a delay, the monkeys were prompted to select the same image on the screen from a sampling which included 1-7 other images. Five monkeys (all rhesus, Macaca mulatta) were involved in the experiment and were trained for two years to perform to a 70-75 per cent proficiency in the task.

The movement of the monkeys' arms were tracked with a camera and translated to movements of the cursor on the screen; they were awarded with a drop of juice when they correctly matched an image.

The prosthesis was placed into two cortical layers L2/3 and L5 of the brain and recorded brain activity within structures known as minicolumns in the prefrontal cortex area.

Once it was confirmed that minicolumn communication between layers L2/3 and L5 was involved in decision making, it was supressed by administering the dopamine-modifying drug, cocaine, to the monkeys. The task was performed again but this time the researchers deployed a 'multi-input multi-output nonlinear' (MIMO) model to stimulate the neurons that were used i
'/>"/>

Contact: Michael Bishop
michael.bishop@iop.org
01-179-301-032
Institute of Physics
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Neuralstem ALS Stem Cell Trial Featured on Fox Atlanta
2. Neuralstem President and CEO to Update Ongoing ALS and NSI-189/Major Depressive Disorder Trials at 2012 Biotech Showcase
3. Neuralstem President and CEO to Present at BIO CEO & Investor Conference 2012
4. Neuralstem Announces Closing of $5.2-Million Registered Direct Offering
5. Fourteenth Patient Dosed in Neuralstem ALS Stem Cell Trial
6. Neuralstem CEO to Present at the World Stem Cells and Regenerative Medicine Congress in London
7. Triangles guide the way for live neural circuits in a dish
8. PhoenixSongs Biologicals, Inc. Announces Enhanced Neural Lineage-specific Cell Culture Media Products Release
9. Neuralstem Receives Notice Of Issuance For Patent Covering Human Neural Cell Transplantation For Neurodegenerative Conditions
10. Neuralstem President And CEO To Present At The 2012 Rodman & Renshaw Annual Healthcare Conference
11. Neuralstem Cells Induce Significant Functional Improvement In Permanent Rat Spinal Cord Injury, Cell Study Reports
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... , Aug. 19, 2014   Synthetic Biologics, ... developing novel anti-infective biologic and drug programs targeting ... announced today that its novel C. difficile ... 54 th Interscience Conference on Antimicrobial Agents ... Washington D.C. Synthetic Biologics, ...
(Date:8/18/2014)... -- A new therapy developed by researchers at ... of Medicine and Columbia University Medical Center (CUMC) ... cardiovascular disease treatment. , The researchers demonstrated ... therapy could selectively inhibit blood vessel re-narrowing and ... using a balloon catheter to open narrowed or ...
(Date:8/18/2014)... unprecedented efficiency and data storage may someday ... electric polarizations to read and write digital ... data-driven technology. But ferroelectrics must first overcome ... curious habit of "forgetting" stored data. ... of Energy,s Brookhaven National Laboratory have discovered ...
(Date:8/18/2014)... 2014 TNI BioTech, Inc. (OTC-BB: TNIB) ("we" ... and marketing of innovative therapies for autoimmune diseases in ... a second notice of TNI BioTech,s annual meeting of ... Noreen Griffin , founder and CEO of TNI ... participation in the Annual Meeting. On behalf of our ...
Breaking Biology Technology:Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 2Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 3Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 4Selective therapy may improve artery repair after interventional cardiovascular procedures 2Selective therapy may improve artery repair after interventional cardiovascular procedures 3Promising ferroelectric materials suffer from unexpected electric polarizations 2Promising ferroelectric materials suffer from unexpected electric polarizations 3Promising ferroelectric materials suffer from unexpected electric polarizations 4TNI BioTech Inc., provides 2nd Notice of Annual Meeting September 4, 2014 2TNI BioTech Inc., provides 2nd Notice of Annual Meeting September 4, 2014 3TNI BioTech Inc., provides 2nd Notice of Annual Meeting September 4, 2014 4
... N.C., Feb. 25 Attagene Inc., a,biotechnology ... analysis, announced today that one of the ... FACTORIAL(TM). In,advance online publication on Nature Methods, ... novel and remarkably consistent method for,simultaneously reporting ...
... 25 t2cure, a clinical,stage biopharmaceutical company developing ... today that it has appointed,Dr. Petra Rueck Head ... have Petra join our company", said Manfred Ruediger,CEO ... project,management will be of critical importance to t2cure ...
... ADVENTRX Pharmaceuticals,Inc. (Amex: ANX ) announced today that ... President of ImClone Systems Incorporated, will,join its Board of ... size of its Board from six to seven directors., ... Board of Directors. He brings,tremendous knowledge and expertise within ...
Cached Biology Technology:Attagene's Breakthrough Transcription Factor Profiling Technology to be Described in Nature Methods 2Attagene's Breakthrough Transcription Factor Profiling Technology to be Described in Nature Methods 3Stem Cell Company t2cure Appoints Dr Rueck Head of Clinical Operations 2Eric K. Rowinsky Joins ADVENTRX Board of Directors 2Eric K. Rowinsky Joins ADVENTRX Board of Directors 3Eric K. Rowinsky Joins ADVENTRX Board of Directors 4
(Date:8/19/2014)... fish purchased at retail seafood counters in 10 ... can expose consumers to unexpectedly high levels of ... falsely present a fish of the same species, ... dangerous mislabeling offense, according to new research by ... labeling of seafood is essential to allow consumers ...
(Date:8/19/2014)... -- ( Aug. 19, 2014 ) -- Scientists at ... to pick up and transfer single cells using a ... slightly. They describe this engineering feat and preliminary test ... of the American Chemical Society . , "Studying single ... in current biomedical research," said nanomedicine department. faculty member ...
(Date:8/19/2014)... who has ever had a glass of fizzy soda ... air. But in a finding with wide industrial applications, ... some particles down into the liquid as well. , ... droplets, so we were surprised, and fascinated, to discover ... same process injected tiny oil droplets into the water," ...
Breaking Biology News(10 mins):Seafood substitutions can expose consumers to unexpectedly high mercury 2Seafood substitutions can expose consumers to unexpectedly high mercury 3Moving single cells around -- accurately and cheaply 2Bubbling down: Discovery suggests surprising uses for common bubbles 2Bubbling down: Discovery suggests surprising uses for common bubbles 3
... Washington DC (February 11, 2010) While many adults consider ... to be obese teens, saddling them with Type-2 diabetes, elevated ... this month in the journal Clinical Pediatrics (published ... point" in obesity often occurs before two years of age, ...
... Sultan, assistant professor of aerospace and ocean engineering at Virginia ... learn he has received a National Science Foundation (NSF) Faculty ... list of more than 70 Virginia Tech CAREER award winners, ... of Engineering since the award was created in 1994. He ...
... modifications to proteins called histones, which are found in ... which DNA is wound, can be used to predict ... pancreatic cancer, a study by researchers at UCLA,s Jonsson ... two specific histone modifications in tumor cells of patients ...
Cached Biology News:2 years old -- a childhood obesity tipping point? 2Engineer studies tensional integrity of biological structures 2Engineer studies tensional integrity of biological structures 3Predicting prognosis and treatment response in a subset of pancreatic cancer patients 2Predicting prognosis and treatment response in a subset of pancreatic cancer patients 3