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Neumedicines Receives Award of $14 Million from BARDA for Continued Development of HemaMax™ as a Medical Countermeasure to Acute Radiation Exposure
Date:8/14/2014

n that HemaMax™ is safe in healthy volunteers.”

“With BARDA’s continued funding, we are advancing HemaMax™ toward consideration for EUA, which, if granted, would allow for its use in the event of a radiological/nuclear emergency,” she added. “We believe HemaMax™ could have a significant impact in saving lives in such an event, and our team is committed to advancing HemaMax™ so that it may soon be a component of the United States’ arsenal in countering radiological/nuclear emergencies.”

Research and development of HemaMax™ for HSARS has been funded entirely with federal funds from the Biomedical Advanced Research and Development Authority, Office of the Assistant Secretary for Preparedness and Response, Office of the Secretary, Department of Health and Human Services, under Contract Nos. HHSO1002000800060C and HHSO100201100037C.

“We are also focused on developing rHuIL-12 as an immunotherapy for cancer patients to be used in combination with various cancer treatments, including radiation, chemotherapies, and other immunotherapies. The promise of IL-12 as an immunotherapy is substantiated by the fact that the National Cancer Institute (NCI) and the Cancer Immunotherapy Trials Network (CITN) consider IL-12 a Priority Agent and rank it the top priority vaccine adjuvant and the third overall immunotherapy agent, only behind IL-15 and anti-PD-1,” Dr. Basile stated.

About HemaMax™:

HemaMax™ (rHuIL-12) holds considerable value and promise playing a central role in linking and regulating both innate (early nonspecific) and adaptive (late specific) immunity, while also playing a critical role in hematopoietic cell-to-cell signaling. In addition to HSARS, HemaMax™ is also being developed for various indications in oncology, including cutaneous T cell lymphoma (CTCL), acute myeloid leukemia (AML), melanoma, solid tumors, various immunotherapy applications, and hematopoietic support.

About Neumedicines Inc.:

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