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Neue Studien beweisen die tödliche Verbindung zwischen Alkohol, Gewicht und Lebererkrankungen bei Frauen
Date:4/24/2013

Patienten untersucht, die aufgrund einer alkoholischen Leberkrankheit im Endstadium Transplantate erhalten hatten, um die Auswirkungen sowohl der Fettleber als auch metabolischer Risikofaktoren wie Fettleibigkeit und Typ-2-Diabetes auf die Entwicklung von HZK an Patienten analysieren zu können.

Die Ergebnisse zeigen, dass die meisten Patienten mit HZK regelmäßig an Übergewicht (54 % gegenüber 14 % der nicht-HZK-Patienten) oder an Diabetes litten (43 % gegenüber 22 % der nicht-HZK-Patienten). Die Hälfte (50 %) der Patienten mit Fettlebererkrankung, Übergewicht, Fettleibigkeit oder Typ-2-Diabetes wiesen HZK auf, verglichen mit nur 6 % der an HZK leidenden Patienten ohne diese anderen Erkrankungen.

Dr. Prati kommentierte: "Fettleber und Alkohol sind schon lange als Risikofaktoren für HZK bekannt, aber diese Studie untersuchte ihre kombinierten Auswirkungen auf Patienten mit Alkoholzirrhose. Diese Erkenntnisse zeigen, dass Patienten, die an Alkoholzirrhose leiden und zudem in der Vergangenheit an Leberverfettung, Fettleibigkeit oder Typ-2-Diabetes erkrankt waren, mit höherer Wahrscheinlichkeit an Leberkrebs erkranken. Die Ergebnisse werden hilfreich sein für die Behandlung von Zirrhosepatienten und die frühzeitige Krebserkennung."

Weltweit sind HZK für etwa 5,4 % aller Krebserkrankungen verantwortlich [4], und sie verursachen 695.000 Todesfälle pro Jahr [5], darunter 47.000 Todesfälle pro Jahr in Europa. [6]

Europa hat weltweit den höchsten Alkoholkonsum. Jeder Siebente Erwachsene trinkt mehr als die empfohlene Tagesmenge Alkohol. [7]

Haftungsausschluss: Die in dieser Mitteilung enthaltenen Datenverweise basieren auf dem eingereichten Auszug. Im Rahmen des International Liver Congress™ 2013 könnten neuere Daten präsentiert werden.

Hinweise für die Redak
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SOURCE The European Association for the Study of the Liver (EASL)
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