Navigation Links
Nebulized Formoterol Fumarate Has Comparable Pharmacokinetic and Pharmacodynamic Profile to Dry Powder Formulation
Date:5/20/2008

ulty coordinating the use of other devices as their disease progresses, nebulized Perforomist(TM) offers an effective, long-term treatment option."

The first study was a single-dose, double-blind, double-dummy crossover dose-ranging study conducted in 47 patients to establish the dose of Perforomist(TM) Inhalation Solution comparable to that of the marketed DPI, Foradil(R) Aerolizer(R). Mean FEV(1) AUC(0-12) (standardized area under the curve for FEV(1) over twelve hours) following FFIS treatment ranged from 1.3 to 3.0 L/hr in a dose-related manner, with identical values (2.3 L/hr) for Perforomist(TM) Inhalation Solution 20mcg and Foradil(R) Aerolizer(R). All other spirometry measures were comparable between FFIS and FA.

The second study involving thirteen COPD patients was a randomized, single-dose, open-label, crossover study comparing FFIS 10, 20, and 24mcg with Foradil(R) Aerolizer(R), which confirmed pharmacokinetic comparability between Perforomist(TM) Inhalation Solution 20mcg by nebulization and Foradil(R) Aerolizer(R) 12mcg (Foradil) by DPI.

"This research continues to support and highlight the clinical value of Perforomist(TM) Inhalation Solution," said Carolyn Myers, Ph.D., President of Dey, L.P. "We thank all of these eminent researchers for their contributions to the trials that were presented today and we remain dedicated to developing nebulized treatment options for those suffering from serious respiratory illnesses such as COPD."

For those attending ATS 2008, the presentations are available as follows:

Poster viewing: Session ID C42 COPD Pharmacotherapy I: Effects of

Bronchodilators

Tuesday, May 20, 2008, 10:45 a.m. - 12:30 p.m. EDT

Metro Toronto Convention Center; Area F: Halls A-B North Building, Level

300

-- Poster #F13: Dose-Ranging Study in COPD Patients Comparing

Pharmacodynamics of Formoterol Fumarate Delivered by Nebulization and

DPI

-- Poster #F
'/>"/>

SOURCE Dey L.P.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Mylan Inc. Subsidiary, Dey, L.P., Announces that Perforomist(TM) (Formoterol Fumarate) Inhalation Solution is Now Available for Maintenance Treatment of COPD
2. New Patient Satisfaction Study With budesonide/formoterol Combination Therapy and fluticasone/salmeterol Combination Therapy in Adults With Asthma
3. ANX-514 Reduces Hypersensitivity Reactions Without Impacting Pharmacokinetics or Antitumor Activity in Preclinical Tests
4. ADVENTRX to Present Complete ANX-530 Pharmacokinetic Data at the 2008 American Association for Cancer Research Annual Meeting
5. PharmAthene Completes Pharmacokinetic Studies of Protexia(R); Program on Target for IND Filing in 2008
6. Halozyme Therapeutics Presents Favorable New Safety and Pharmacokinetic Data on rHuPH20 Enzyme Produced Via New Manufacturing Process at European Federation for Pharmaceutical Sciences
7. ANX-530 Demonstrates Equivalent Pharmacokinetics to Navelbine(R) in a Registrational Bioequivalence Clinical Study
8. Safety Profile of TAXUS(R) Liberte(TM) Stent System Highlighted in Worlds Largest Stent Registry
9. Clarient to Commercialize Novel Breast Cancer Profile
10. Finesse Solutions, LLC Announces OPC Connectivity With Nova BioProfile 400
11. Derma Sciences MEDIHONEY(TM) Profiled in Several Television News Health Reports
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2015)... Sanofi, a global and ... quarter of 2015. CEO Olivier Brandicourt ... in different businesses. Watch video interview ... Topics covered in the interview include:  ... Performance drivers - Diabetes ...
(Date:7/29/2015)... MONTREAL , July 29, 2015 /PRNewswire/ - BioAmber Inc. ... Laurin , the Company,s Chief Financial Officer has resigned.  ... former Chief Financial Officer who retired in December 2014, ... search for a permanent successor.     Andy ... Mr. Laurin and ensure a smooth transition.  Andy was ...
(Date:7/29/2015)... ... 29, 2015 , ... Brady (NYSE:BRC), a global leader in ... To align chemical container labeling with OSHA’s updated Hazard Communication (HazCom) Standard and ... example of an accurate label, and pictogram uses and meanings. , “With changes ...
(Date:7/29/2015)... ... 2015 , ... The third Medical Innovation Impact Index (MI3) Alert considers FDA ... combinations. The current system received a score of 0 (range -10 to +10) for ... of Fairleigh Dickinson University’s ( FDU ) Rothman Institute of Innovation and Entrepreneurship. ...
Breaking Biology Technology:BioAmber Announces Change in Chief Financial Officer 2BioAmber Announces Change in Chief Financial Officer 3Brady Announces a New GHS Label Guide 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 2Third Medical Innovation Impact Index Issued by Fairleigh Dickinson University’s Initiative for Patient-Centered Innovation (iPCI) 3
... $17.8 million at June 30 ... September 5, NAPA, Calif., Aug. 14 Senetek PLC ... development,of technologies that target the science of healthy aging, today ... Revenue for the quarter ended June 30, 2008 was $691,000, ...
... P. Loukas, Industry Veteran, Named as CEO ... Named as President and COO, ALTAMONTE SPRINGS, Fla., ... biotechnology company focused on,in-licensing and commercialization of niche oncology ... Chief Executive Officer,effective August 12, 2008. Current President, CEO ...
... Profit Attributable to Shareholders Increased Significantly by ... Fufeng Group Limited,("Fufeng" or "the Group"; HKEx: 546), ... in China, today announces,its interim results for the ... the period under review, driven by the increased ...
Cached Biology Technology:Senetek PLC Reports Second Quarter 2008 Financial Results 2Senetek PLC Reports Second Quarter 2008 Financial Results 3Milestone Biosciences, LLC Further Strengthens Executive Management Team 2Fufeng Announces 2008 Interim Results With Strong Sign of Recovery 2Fufeng Announces 2008 Interim Results With Strong Sign of Recovery 3
(Date:7/27/2015)... SAN JOSE, Calif. , July 27, 2015 ... leading developer of human interface solutions, today announced ... ClearPad ® touchscreen solution for its stylish ... controller for its proven reliability, low power and ... with a wet finger. Huawei designers also required ...
(Date:7/23/2015)... , July 23, 2015 Research ... addition of the "Global Outlook of the ... offering. The global biometrics market ... public and commercial applications owing to the uptake ... witness a transformation that enhances the growth of ...
(Date:7/21/2015)... 21, 2015 Passwords have proven futile ... the recent U.S. Office of Personnel Management breach. ... infosec conundrum, but developers and end-users are concerned ... this dilemma, Biometrics-as-a-Service provider HYPR Corp. announced today ... for third party integration. A ...
Breaking Biology News(10 mins):Synaptics Touchscreen Solution Powers New Huawei Watch 2Synaptics Touchscreen Solution Powers New Huawei Watch 3Global Outlook of the Biometrics Industry 2015 2Global Outlook of the Biometrics Industry 2015 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 2HYPR Corp. Launches Industry First Biometric Tokenization Platform 3HYPR Corp. Launches Industry First Biometric Tokenization Platform 4
... Understanding forest biodiversity and how carbon dioxide is stored ... The bigger the tree, the more carbon it stores ... global variance in tree height, identifying temperature as the ... gives canopy trees, the focus of much forest carbon ...
... VEGAS , Jan. 7, 2014 from ShowStoppers @ ... Vapor X personalized, rechargeable vaporizer unit will become available ... for the 2014 holiday retail season. There will be a ... today during ShowStoppers at CES 2014, Booth # A5. ...
... women are choosing science careers, yet women are notoriously ... careers due to pessimism about advancement. New research suggests ... teams that organize symposia could offer a simple, effective ... in obtaining science degrees over the past four decades. ...
Cached Biology News:Vapor Corp. Unveils E-Cigarette Industry's First Biometric Technology 2Boost careers of female scientists: Make sure women help choose meeting speakers 2Boost careers of female scientists: Make sure women help choose meeting speakers 3
... The BioGenex VISION Sytem is a ... comes with proprietary digital imaging and ... digital image acquisition, analysis, archving/retrieval and ... a state-of-the-art digital imaging system that ...
... -mr agarose is specifically for ... endoosmosis, and is recommended for ... weight proteins or complexes that ... of molecular sieving in polyacrylamide ...
... agarose is used for second-dimension SDS-PAGE ... in place in PROTEAN Plus cells. ... to allow monitoring of electrophoresis runs. ... agarose in 1x Tris, glycine, SDS, ...
The Trans-Blot Plus gel and cassette assembly tray is used to hold the Trans-Blot Plus gel holder cassette, buffer, and other materials for the gel and membrane sandwich during their assembly....
Biology Products: