Navigation Links
Nature article focuses on tinnitus treatment
Date:1/12/2011

Targeted nerve stimulation could yield a long-term reversal of tinnitus, a debilitating hearing impairment affecting at least 10 percent of senior citizens and up to 40 percent of military veterans, according to an article posted in the Jan. 12 online edition of Nature.

Researchers Dr. Michael Kilgard and Dr. Navzer Engineer from The University of Texas at Dallas and University-affiliated biotechnology firm MicroTransponder report that stimulation of the vagus nerve paired with sounds eliminated tinnitus in rats. A clinical trial in humans is due to begin in the next few months.

Described as a ringing in the ears, tinnitus causes mild irritation for some people but is disabling and painful for many others. The U.S. Veterans Administration spends about $1 billion a year on disability payments for tinnitus, said Kilgard, associate professor in the School of Behavioral and Brain Sciences at UT Dallas and co-author of the journal article.

"Brain changes in response to nerve damage or cochlear trauma cause irregular neural activity believed to be responsible for many types of chronic pain and tinnitus," he said. "But when we paired tones with brief pulses of vagus nerve stimulation, we eliminated the physiological and behavioral symptoms of tinnitus in noise-exposed rats."

The researchers are, in essence, retraining the brain to ignore the nerve signals that simulate ringing. They monitored the laboratory rats for several weeks after therapy, and the improvements persisted.

"This minimally invasive method of generating neural plasticity allows us to precisely manipulate brain circuits, which cannot be achieved with drugs," said Dr. Navzer Engineer, vice president of preclinical affairs at MicroTransponder and lead author on the study. "Pairing sounds with VNS provides that precision by rewiring damaged circuits and reversing the abnormal activity that generates the phantom sound."

The research team is dev
'/>"/>

Contact: Emily Martinez
emily.martinez@utdallas.edu
972-883-4335
University of Texas at Dallas
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. DOE JGI Director Eddy Rubin highlights the genomics of plant-based biofuels in the journal Nature
2. Natures Premium(R) Brand First Fresh Pork in North America to Carry DNA TraceBack(R) Seal of Authenticity
3. James L. Wittliff, Ph.D., FACB, to Present Predicting Breast Cancer Outcome with Gene Expression Signatures on the Ziplex(R) System at the Association for Molecular Pathology Conference, October 30
4. Genetic clock makers at UC San Diego publish their timepiece in Nature
5. MySignatureBook Certified Compliant With SAFE-BioPharma Digital Standard(TM)
6. Webcast Alert: Regulus Therapeutics, Alnylam Pharmaceuticals and Isis Pharmaceuticals Announce New Nature Publication on miR-21 Conference Call
7. Nature Medicine study shows Peregrines bavituximab can cure lethal virus infections
8. Research Published in Nature Medicine Shows Disruption of Chemokine Interactions Inhibits Atherosclerosis in Mice
9. Data Published in Nature Cell Biology Reveal Novel Function of Drug Target EpCAM in Cancer Cell Signalling
10. Light-speed nanotech: Controlling the nature of graphene
11. Nature Reviews Publishes Article About Jennerexs Multi-Mechanistic Cancer Therapeutic
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... 05, 2015 Research and Markets ... the "Clinical Laboratory, Molecular Diagnostics and Genomic ... 2019 - Global Version" report to their ... the area of molecular diagnostics and pharmacogenics hold ... world market that is moving out of the ...
(Date:5/5/2015)... May 05, 2015 Exotic ... distributor, announces the launch of http://www.cng.exoticautomation.com , ... with a convenient way to purchase genuine OEM ... . , The new website provides owners ... with direct access to high performance products for ...
(Date:5/4/2015)... 4, 2015 Many of us take ... certain infants with rare, inherited mutations of certain ... of their impaired immune responses. Now, ... an important role for calcium signaling in immune ... the bacterium causing tuberculosis (TB). ...
(Date:5/4/2015)...  Tikcro Technologies Ltd. (OTCQB: TIKRF) announced today that ... for the fiscal year ended December 31, 2014 with ... report on Form 20-F contains information regarding its biotechnology ... of cancer immune checkpoints. This project aims to develop ... binding in targeting certain identified immune checkpoints. The filing ...
Breaking Biology Technology:Global Clinical Laboratory, Molecular Diagnostics and Genomic Testing Services Market Trends and Forecast 2015 to 2019 2Exotic Automation & Supply Launches Ecommerce Website 2Researchers Discover A Novel And Unexpected Role For Calcium In Controlling Inflammation During Chronic Lung Infection 2Researchers Discover A Novel And Unexpected Role For Calcium In Controlling Inflammation During Chronic Lung Infection 3Tikcro Technologies Files Annual Report on Form 20-F for the Year Ended December 31, 2014 2
... exclusive, distribution agreement with AZPA International Inc. for Australia and New ... ... LAVAL, QC, Dec. 19 /PRNewswire-FirstCall/ - Neptune Technologies &,Bioressources Inc. ("Neptune") ... an exclusive distribution agreement with,AZPA International Inc. ("AZPA International") for Australia ...
... collaborators, LineaGen is leveraging new funding round, Utah Population ... platform for commercializing first-in-class molecular diagnostic ... ... Inc.,( http://www.LineaGen.com ), a biomarker discovery company created to,discover and commercialize ...
... the Announcement of a Tracking Program for,Cloned Livestock, ... a,statement by International Dairy Foods Association President and ... a new national registry to track cloned,livestock as ... over food,products from cloned animals. However, we strongly ...
Cached Biology Technology:Nationwide product launch of NKO(R) planned for February 2008 in Australia and New Zealand 2Nationwide product launch of NKO(R) planned for February 2008 in Australia and New Zealand 3LineaGen Inc. Launches With Close of $5.8 Million Series A Funding Round 2LineaGen Inc. Launches With Close of $5.8 Million Series A Funding Round 3LineaGen Inc. Launches With Close of $5.8 Million Series A Funding Round 4Statement of International Dairy Foods Association President and CEO Connie Tipton 2
(Date:4/20/2015)... The announcement comes as demand for fire ... Ireland,s foremost records management company, has ... an impressive track record of clients within the first 12 ... management sector in Dubai . As a ... employ a further eight staff members at its Irish headquarters. ...
(Date:4/14/2015)... YORK , April 14, 2015  HYPR ... IDentity Online (FIDO ® ) Alliance tm , ... specifications. FIDO members commit to share technology and ... methods that are interoperable, more secure and private, ... enable biometric identity verification that protects sensitive user ...
(Date:4/13/2015)... , April 13, 2015 ... TechSci Research, "Global Biometrics Market Forecast & Opportunities, 2020", ... a CAGR of around 14% till 2020. The ... for large scale implementation and review of biometric ... launch of new products with greater efficiency, are ...
Breaking Biology News(10 mins):Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 2Glenbeigh Records Management Wins Contract With Dubai Islamic Bank 3HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2
... in Hong Kong this year. So far, 466 children were infected ... Streptococcus pyogenes, a gram-positive pathogen that can be transmitted via ... Hong Kong Center for Disease Control (HK CDC), Hong Kong University ... the S. pyogenes strain that was isolated from a ...
... Va. recently found a way to improve electricity generating ... less expensive. Specifically, they discovered a way to speed ... which are necessary for fuel cells to operate. ... membrane, or PEM, commonly used in fuel cells and ...
... and the USDA Agricultural Research Service have developed a new ... boniato, or tropical sweet potato, Liberty has a dark red ... Boniato potatoes originated in the tropical Americas and are grown ... served fried, mashed or in soup. "We developed Liberty ...
Cached Biology News:Hong Kong University leads the genomics research of scarlet fever pathogen 2Stretching old material yields new results for energy- and environment-related devices 2
Fast, sensitive quantitation of Mouse IgM concentration....
Detect and measure levels of mouse IgG3 antibody isotypes quickly and easily....
Request Info...
ExonBio Service provides one-stop recobinant protein shopping from cloning, expression and purification. Price including gene cloning....
Biology Products: