Navigation Links
Nature article focuses on tinnitus treatment
Date:1/12/2011

Targeted nerve stimulation could yield a long-term reversal of tinnitus, a debilitating hearing impairment affecting at least 10 percent of senior citizens and up to 40 percent of military veterans, according to an article posted in the Jan. 12 online edition of Nature.

Researchers Dr. Michael Kilgard and Dr. Navzer Engineer from The University of Texas at Dallas and University-affiliated biotechnology firm MicroTransponder report that stimulation of the vagus nerve paired with sounds eliminated tinnitus in rats. A clinical trial in humans is due to begin in the next few months.

Described as a ringing in the ears, tinnitus causes mild irritation for some people but is disabling and painful for many others. The U.S. Veterans Administration spends about $1 billion a year on disability payments for tinnitus, said Kilgard, associate professor in the School of Behavioral and Brain Sciences at UT Dallas and co-author of the journal article.

"Brain changes in response to nerve damage or cochlear trauma cause irregular neural activity believed to be responsible for many types of chronic pain and tinnitus," he said. "But when we paired tones with brief pulses of vagus nerve stimulation, we eliminated the physiological and behavioral symptoms of tinnitus in noise-exposed rats."

The researchers are, in essence, retraining the brain to ignore the nerve signals that simulate ringing. They monitored the laboratory rats for several weeks after therapy, and the improvements persisted.

"This minimally invasive method of generating neural plasticity allows us to precisely manipulate brain circuits, which cannot be achieved with drugs," said Dr. Navzer Engineer, vice president of preclinical affairs at MicroTransponder and lead author on the study. "Pairing sounds with VNS provides that precision by rewiring damaged circuits and reversing the abnormal activity that generates the phantom sound."

The research team is dev
'/>"/>

Contact: Emily Martinez
emily.martinez@utdallas.edu
972-883-4335
University of Texas at Dallas
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. DOE JGI Director Eddy Rubin highlights the genomics of plant-based biofuels in the journal Nature
2. Natures Premium(R) Brand First Fresh Pork in North America to Carry DNA TraceBack(R) Seal of Authenticity
3. James L. Wittliff, Ph.D., FACB, to Present Predicting Breast Cancer Outcome with Gene Expression Signatures on the Ziplex(R) System at the Association for Molecular Pathology Conference, October 30
4. Genetic clock makers at UC San Diego publish their timepiece in Nature
5. MySignatureBook Certified Compliant With SAFE-BioPharma Digital Standard(TM)
6. Webcast Alert: Regulus Therapeutics, Alnylam Pharmaceuticals and Isis Pharmaceuticals Announce New Nature Publication on miR-21 Conference Call
7. Nature Medicine study shows Peregrines bavituximab can cure lethal virus infections
8. Research Published in Nature Medicine Shows Disruption of Chemokine Interactions Inhibits Atherosclerosis in Mice
9. Data Published in Nature Cell Biology Reveal Novel Function of Drug Target EpCAM in Cancer Cell Signalling
10. Light-speed nanotech: Controlling the nature of graphene
11. Nature Reviews Publishes Article About Jennerexs Multi-Mechanistic Cancer Therapeutic
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... Ed Bilsky, Ph.D., vice president for Research ... in the Neurosciences (CEN), and professor of pharmacology at ... a member of the prestigious Dana Alliance for Brain ... to receive this honor. , The Dana Alliance ... Dana Foundation. Its mission is to advance public ...
(Date:12/19/2014)... Boston, MA (PRWEB) December 18, 2014 ... software, announced the appointment of Siri Bryant as the ... the new Director of Core Implementations. These two new ... provide outstanding customer service by ensuring that iLab continues ... , “In the last four years, iLab has been ...
(Date:12/19/2014)... The empty capsules market is ... population and technological innovations in the empty capsules ... catalysing the growth of the empty capsules market. ... , Scope of Report , The report will ... entrants/smaller firms to gauge the pulse of the ...
(Date:12/19/2014)... , Dec. 18, 2014  Decision Resources Group ... dental biomaterial market will grow moderately through 2023 as ... and growing awareness of dental biomaterials all spur procedure ... such as China and ... bring dental procedures within reach for a larger proportion ...
Breaking Biology Technology:UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 2UNE's Ed Bilsky Named Member of Dana Alliance for Brain Initiatives 3iLab Solutions Announces Two New Leadership Positions to Meet the Needs of Its Growing Customer Base 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 2Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 3Empty Capsules Market Hit to Reach $1,820 Million by 2019 - New Research Report by MarketsandMarkets 4Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 2Asia Pacific Dental Biomaterial Market Will Grow Strongly Through 2023 3
... SupraNet Communications, Inc. , an Internet service provider, ... infrastructure, allowing them to provide Internet services to businesses ... options. , ,The new OC12 from Charter Business ... businesses throughout the southern half of state where Charter ...
... write about these days stirs as much feedback as my ... blog tools, search, social networks, and syndication technologies. , ,Over ... of social networks to a cautious blogger, and now an ... disruptive force that is fundamentally changing communications on every facet. ...
... has received a $500,000 federal research grant, the ... II small-business innovation research grant from the National ... treatment. The funding complements the $100,000 phase I grant ... , ,According to Sal Braico, ConjuGons chief operating officer, ...
Cached Biology Technology:Rural Wisconsin businesses gain high-speed net access 2Changing perspectives on social networks 2Changing perspectives on social networks 3ConjuGon receives $500,000 to battle bacteria 2
(Date:11/21/2014)... , November 18, 2014 According ... Market by Systems (Video, RFID, Access Control, Intrusion Detection, ... Hotels, Banks, Government), Component Service Geography - Global Forecasts ... Market is projected to be around $25 Billion in ... 2020, growing at a CAGR of 8.69%. ...
(Date:11/21/2014)... 2014   Atmel® Corporation (NASDAQ: ... touch technology solutions, today launched the industry,s first family ... widest V cc range from 1.7V to 5.5V. ... I 2 C bus communication speeds, and are available ... them ideal for consumer, industrial, computer, and medical applications. ...
(Date:11/18/2014)... Nov. 18, 2014   EyeLock Inc. , ... and MorphoTrust USA (Safran), a leading ... announced a strategic partnership to offer comprehensive biometric ... administration (MVA), airport screening and financial services markets. ... MorphoTrust serves consumers through a nationwide network of ...
Breaking Biology News(10 mins):Industrial Security Systems Market Worth $38 Billion by 2020 2Industrial Security Systems Market Worth $38 Billion by 2020 3Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 2Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 3Atmel Launches Industry's First Wide-V(cc) Low-Power Temperature Sensor Family 4EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 2EyeLock, MorphoTrust Form Strategic Partnership to Pursue Commercial Enterprise Deployments 3
... Reproductive medicine is one of today,s most exciting ... of medical ,firsts, new rulings by regulatory bodies or ... in the field, ethicists, legislators, the media and the ... All sessions are open to journalists and registration is ...
... It might sound like a mashup of monster movies, ... attacked its prey, reconstructing a killing that took place 4 ... is incredibly rare, but by careful, forensic-style analysis of bite ... based in Pisa, Italy, have reconstructed the events that led ...
... , This release is available in French . ... Dr. Hanadi Sleiman has achieved a major breakthrough in the development ... drugs to specific diseased cells. Sleiman explains that the research involves ... used as the genetic code for life, it becomes a kind ...
Cached Biology News:ESHRE Annual Meeting, June 27-30 in Rome 2Jaws -- 4 million B.C. 2
...
... Product Rabbit polyclonal to JNK1 (phospho T183 ... to an internal domain containing phosphorylated T183/Y185. ... and Rat. Not yet tested in other species. ... several subgroups, including the ERK, JNK, and p38 ...
Dako Target Retrieval Solution, Citrate pH 6 (x 10) For more information, please visit Dako' web-site. EU regulatory status: CE US regulatory status: IVD...
... solid. Increases the expression of glutathione peroxidase. ... 2 O. Unstable in aqueous solutions; reconstitute ... 3211-76-5, M.W. 196.1. References: Merck Index ... A.F. 1995. Biochem. J. 306, ...
Biology Products: