Navigation Links
Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections
Date:3/20/2009

ral infection of cells. Our data go a step further, providing compelling evidence that exposed PS itself is a promising anti-viral drug target that is involved in the pathogenesis of multiple viruses, suggesting the possibility of achieving broad-spectrum anti-viral effects using a single anti-PS agent. We look forward to further exploring the potential of bavituximab and other anti-PS antibodies against viruses for which there are few or no effective therapeutic options."

In the first study, 100% of mice infected with lethal murine CMV and treated with bavituximab recovered fully, while only 25% of control animals survived. In the second study, guinea pigs were infected with lethal Pichinde virus, which is a model virus for Lassa fever. Fifty percent of the bavituximab-treated group survived, while untreated animals all died. In this study, the anti-viral effect of bavituximab was further augmented by the addition of the standard of care drug ribavirin, with 63% of animals receiving the combination therapy surviving the potentially lethal infection.

"We are extremely pleased to see this research demonstrating the broad anti-viral potential of bavituximab and our anti-PS technology platform published in this highly regarded journal," said Steven W. King, president and CEO of Peregrine. "This new publication is the latest in a series of external validations of our anti-viral program. It follows a recently awarded federal government contract for assessment of anti-PS antibodies to treat viral hemorrhagic fevers, research on the role of PS in viral infections that was published in a leading science journal earlier this year, and a recent presentation on anti-PS antibodies at a global HIV conference."

Mr. King added, "Better prevention and treatment of viral diseases are urgently needed, and we are increasingly optimistic that bavituximab and our other anti-PS antibodies could be valuable contributors to the field."

PS i
'/>"/>

Contact: Barbara Lindheim
blindheim@biocompartners.com
212-918-4650
BioCom Partners
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Nature Reviews Publishes Article About Jennerexs Multi-Mechanistic Cancer Therapeutic
2. Light-speed nanotech: Controlling the nature of graphene
3. Data Published in Nature Cell Biology Reveal Novel Function of Drug Target EpCAM in Cancer Cell Signalling
4. Research Published in Nature Medicine Shows Disruption of Chemokine Interactions Inhibits Atherosclerosis in Mice
5. Nature Medicine study shows Peregrines bavituximab can cure lethal virus infections
6. Webcast Alert: Regulus Therapeutics, Alnylam Pharmaceuticals and Isis Pharmaceuticals Announce New Nature Publication on miR-21 Conference Call
7. MySignatureBook Certified Compliant With SAFE-BioPharma Digital Standard(TM)
8. Genetic clock makers at UC San Diego publish their timepiece in Nature
9. James L. Wittliff, Ph.D., FACB, to Present Predicting Breast Cancer Outcome with Gene Expression Signatures on the Ziplex(R) System at the Association for Molecular Pathology Conference, October 30
10. Natures Premium(R) Brand First Fresh Pork in North America to Carry DNA TraceBack(R) Seal of Authenticity
11. DOE JGI Director Eddy Rubin highlights the genomics of plant-based biofuels in the journal Nature
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/12/2014)... -- Research and Markets has announced the ... Report 2014" report to their offering. ... is a professional and in-depth study on the current ... The report provides a basic overview of ... structure. The dry film photoresist market analysis is provided ...
(Date:9/11/2014)... (PRWEB) September 12, 2014 RURO, ... radio-frequency identification (RFID) solutions and sample management solutions ... , RURO completed work on the most recent ... and it has already seen mass adoption, especially ... release of version 5.0 brought an entirely new ...
(Date:9/11/2014)... thick sheet of carbon, can be randomly decorated with ... that could have a significant impact on the chemical, ... provide an ultra-strong, non-corrosive coating for a wide range ... be used to paint various surfaces ranging from glass ... chemical treatment, the resulting coatings behave like graphite in ...
(Date:9/11/2014)... 2014 The Registration Committee today ... now open for Pittcon 2015, the world’s largest ... event will be held March 8-12, 2015, at ... , The discounted registration fee of $175 ... 2/20/2015). This affordable price includes unlimited week-long access ...
Breaking Biology Technology:Global Dry Film Photoresist Industry Report 2014 2Limfinity® Version 5.1 Available 2Graphene paints a corrosion-free future 2Conferee Registration Opens for Pittcon 2015; Housing & Travel Open for Reservations 2
... CLEVELAND, Ohio , May 24, 2010 Simbionix ... medical professionals and the healthcare industry, is launching,two new hands-on training systems- ... revealed for the first time at,the AUA annual meeting in San ... , ...
... ... Key Data to Drive Real-time Interactive Life Science Research , ... (PRWEB) May 24, 2010 -- Genedata, a ... announced Genedata Expressionist 6 , which is a major new release of the ...
... , May 24 Dynamic, thorough, and robustly ... our newest Scientific Content Consultant, Philippe Vitat, who brings with ... Mr. Vitat has worked as a certified medical writer and ... of the World" in medical education by the International Biographical ...
Cached Biology Technology:Simbionix to Reveal Two new Products at the Upcoming American Urology Association (AUA) Annual Meeting 2Simbionix to Reveal Two new Products at the Upcoming American Urology Association (AUA) Annual Meeting 3Genedata Expressionist 6 with New Refiner MS Capabilities Debuts at 58th ASMS Conference on Mass Spectrometry 2Genedata Expressionist 6 with New Refiner MS Capabilities Debuts at 58th ASMS Conference on Mass Spectrometry 3Genedata Expressionist 6 with New Refiner MS Capabilities Debuts at 58th ASMS Conference on Mass Spectrometry 4Highly Regarded Medical Writer Joins Avant Healthcare Marketing Team 2
(Date:9/12/2014)... processing from the user,s computer on to remote servers. ... computing power that they can then access from anywhere ... a single desktop or other computer with its finite ... increased energy demands of sustaining distributed servers and having ... laptop might be shut down when it is not ...
(Date:9/12/2014)... types of dendritic cells in human skin have assorted ... psoriasis report researchers in the journal EMBO Molecular ... regulate the composition of dendritic cells in psoriatic skin ... of the disease. , "We urgently need new ... benefits to patients and reduce the incidence of known ...
(Date:9/11/2014)... Chicago residents today might have had a Wisconsin ... Illinois had been approved. It was a straight line ... south of the Rock and Mississippi River confluence. University ... the proposed northern border not been changed, the state ... footprint with the northern 51 miles of the Illinois ...
Breaking Biology News(10 mins):Cutting the cloud computing carbon cost 2Dendritic cells affect onset and progress of psoriasis 2Original northern border of Illinois was south of Chicago and Lake Michigan 2Original northern border of Illinois was south of Chicago and Lake Michigan 3
... the largest scientific conference devoted primarily to osteoporosis, will ... session focused on four key topics in nutrition and ... the MRC Epidemiology Resource Centre at the University of ... the University of Oxford, will speak on the developmental ...
... improve forecasts of dust storms in the American Southwest ... announced the finding as a five-year NASA-funded project nears ... of the University of New Mexico in Albuquerque, and ... scientists evaluated the influence of space-based observations on predictions ...
... year, some 29,000 adults and 2,000 children are diagnosed with ... abnormal production of white blood cells in the bone marrow. ... also destroys normal cells. But what if a way could ... A team of Syracuse University researchers believes it may have ...
Cached Biology News:Nutrition and bone health session to open the IOF World Congress on Osteoporosis in Bangkok 2NASA-enhanced dust storm predictions to aid health community 2NASA-enhanced dust storm predictions to aid health community 3Syracuse University researchers discover new way to attack some forms of leukemia 2Syracuse University researchers discover new way to attack some forms of leukemia 3
... to Salmonella typhimurium The genus Salmonella is ... is composed of Gram-negative bacilli that are facultative ... the "H" or flagellar antigen (phase 1 & ... the LPS moiety) and the "Vi" or capsular ...
... 50 mg/L streptomycin sulfate, 100 mg/L kanamycin ... magnesium chloride. The use of a balanced ... generally attributed to early workers in the ... solution of inorganic salts designed to maintain ...
... The micro 1 is a dramatic breakthrough ... from 1mL with 10nL resolution, the micro 1 ... benchtop dispenser. And, the micro 1 never needs ... , Touch Screen programming on an LCD Display ...
... ( Abpromise for all tested ... Synthetic peptide: VEEESFGPQPISRLE conjugated to KLH, ... 15-29 of Human Rad51 ... Swiss Protein ID: ...
Biology Products: