Navigation Links
Nature Medicine study shows Peregrine's bavituximab can cure lethal virus infections
Date:3/20/2009

ral infection of cells. Our data go a step further, providing compelling evidence that exposed PS itself is a promising anti-viral drug target that is involved in the pathogenesis of multiple viruses, suggesting the possibility of achieving broad-spectrum anti-viral effects using a single anti-PS agent. We look forward to further exploring the potential of bavituximab and other anti-PS antibodies against viruses for which there are few or no effective therapeutic options."

In the first study, 100% of mice infected with lethal murine CMV and treated with bavituximab recovered fully, while only 25% of control animals survived. In the second study, guinea pigs were infected with lethal Pichinde virus, which is a model virus for Lassa fever. Fifty percent of the bavituximab-treated group survived, while untreated animals all died. In this study, the anti-viral effect of bavituximab was further augmented by the addition of the standard of care drug ribavirin, with 63% of animals receiving the combination therapy surviving the potentially lethal infection.

"We are extremely pleased to see this research demonstrating the broad anti-viral potential of bavituximab and our anti-PS technology platform published in this highly regarded journal," said Steven W. King, president and CEO of Peregrine. "This new publication is the latest in a series of external validations of our anti-viral program. It follows a recently awarded federal government contract for assessment of anti-PS antibodies to treat viral hemorrhagic fevers, research on the role of PS in viral infections that was published in a leading science journal earlier this year, and a recent presentation on anti-PS antibodies at a global HIV conference."

Mr. King added, "Better prevention and treatment of viral diseases are urgently needed, and we are increasingly optimistic that bavituximab and our other anti-PS antibodies could be valuable contributors to the field."

PS i
'/>"/>

Contact: Barbara Lindheim
blindheim@biocompartners.com
212-918-4650
BioCom Partners
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Nature Reviews Publishes Article About Jennerexs Multi-Mechanistic Cancer Therapeutic
2. Light-speed nanotech: Controlling the nature of graphene
3. Data Published in Nature Cell Biology Reveal Novel Function of Drug Target EpCAM in Cancer Cell Signalling
4. Research Published in Nature Medicine Shows Disruption of Chemokine Interactions Inhibits Atherosclerosis in Mice
5. Nature Medicine study shows Peregrines bavituximab can cure lethal virus infections
6. Webcast Alert: Regulus Therapeutics, Alnylam Pharmaceuticals and Isis Pharmaceuticals Announce New Nature Publication on miR-21 Conference Call
7. MySignatureBook Certified Compliant With SAFE-BioPharma Digital Standard(TM)
8. Genetic clock makers at UC San Diego publish their timepiece in Nature
9. James L. Wittliff, Ph.D., FACB, to Present Predicting Breast Cancer Outcome with Gene Expression Signatures on the Ziplex(R) System at the Association for Molecular Pathology Conference, October 30
10. Natures Premium(R) Brand First Fresh Pork in North America to Carry DNA TraceBack(R) Seal of Authenticity
11. DOE JGI Director Eddy Rubin highlights the genomics of plant-based biofuels in the journal Nature
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... 27, 2015  CASI Pharmaceuticals, Inc. (Nasdaq: CASI ... and commercialization of innovative therapeutics addressing cancer and other ... commercial focus on China , today ... ended December 31, 2014.  The Company ... per share, for the three months ended December 31, ...
(Date:3/26/2015)... (PRWEB) March 26, 2015 The Market ... formed a strategic alliance with Designing Gig LLC to ... clients. , “Forging this alliance with Designing ... Now we can extend a comprehensive, end-to-end, digital solution ... strategy, and execution,” said Chuck Miller, president of The ...
(Date:3/26/2015)... ReliantHeart, Inc., an innovative supplier of advanced mechanical ... transit-time flow measurement solutions, are collaborating on a miniature ... the HeartAssist5® Left Ventricular Assist Device (LVAD). ... and peace of mind. , The Transonic flow ... 1/6th of the power required by earlier flow board ...
(Date:3/25/2015)... March 26, 2015 Agnition announced today ... of American Farmer, airing for the first time at ... of American Farmer will explore the extremely important role ... producers with a patented Microbial Catalyst™ technology that enhances ... yields. The segment will air again on April 28. ...
Breaking Biology Technology:CASI Pharmaceuticals Reports 2014 Fourth Quarter And Full Year Financial Results 2CASI Pharmaceuticals Reports 2014 Fourth Quarter And Full Year Financial Results 3CASI Pharmaceuticals Reports 2014 Fourth Quarter And Full Year Financial Results 4CASI Pharmaceuticals Reports 2014 Fourth Quarter And Full Year Financial Results 5CASI Pharmaceuticals Reports 2014 Fourth Quarter And Full Year Financial Results 6The Market Element LLC and Designing Gig LLC Form Strategic Alliance 2LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 2LVAD patients to have greater mobility and peace of mind through Transonic and ReliantHeart’s True Flow collaboration for the HeartAssist5® 3Agnition to be Featured In Upcoming Episode of American Farmer on RFD-TV 2
... & Son Inc. made the No. 2 spot in the ... in 2004. The top spot in this year's list of technology ... than S.C. Johnson, made this year's list. , , Information Week ... years, tracking organizations' information technology agendas and usage, and examining their ...
... soon be linked twice daily to 11,000 tech firms ... will be adding nonstop morning and evening flights to ... is home to the federal Centers for Disease Control, ... and life sciences companies. Our technologists, researchers and business ...
... will invest $37.5 million to extend its production facility in ... China and worldwide. , ,The GE Healthcare plant ... the first U.S .FDA approved site for contrast media in ... the U.S. as well as numerous markets throughout the world. ...
Cached Biology Technology:S.C. Johnson lands in No. 2 spot in Information Week 500 list 2
(Date:3/20/2015)... , March 20, 2015 NXT-ID, Inc. (NASDAQ: ... authentication company focused on the growing mobile commerce market, ... is one of the products featured in 2015 "I ... at 11:00 PM EST on the DIY Network.   ... Las Vegas , site of the 2015 ...
(Date:3/18/2015)... 2015 As mobile payments become more ... wallets and apps continue to be introduced into the market ... mobile payment industry in focus today are:  NXT-ID, Inc. (NASDAQ: ... BABA ), Apple Inc. (NASDAQ: AAPL ), ... (NASDAQ: FB ) NXT-ID, Inc. (NASDAQ: ...
(Date:3/17/2015)... , March 17, 2015  MecklerMedia Corporation (OTCQX: ... exhibition for service robots ever held in ... place on May 11-13, 2015 at the Javits ... for the event include: Acorn Product Development; Axis ... Infranor; Kinova Robotics; Littler; NewBotic Corporation; Neya Systems ...
Breaking Biology News(10 mins):NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 2NXT-ID's Wocket Biometric Smart Wallet to Air on "I Want That" International CES Special 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 2Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 3Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 4Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 5Revolutionary Smart Wallet & Mobile Payment Choices Change the Game for Consumers - Company Begins Shipping Newest Digital Wallet to Customers 6MecklerMedia's RoboUniverse New York Announces Sponsors and Exhibitors, May 11-13, 2015 2
... of chemists from the University of Valencia (UV) has ... amphora found among remains at Lixus, in Morocco, was ... inside the 2,000-year-old vessel, which could be fragments of ... of archaeologists from the UV discovered a sealed amphora ...
... Although they are present almost everywhere, on land ... the superphylum Planctomycetes-Verrucomicrobia-Chlamydiae, or PVC, have remained in ... about a decade ago. Scientists at the European ... discovered that these poorly-studied bacteria possess proteins thought ...
... The Genetics Society of America is pleased to announce ... for Professional Development in Genetics. These travel ... and international meetings or enroll in laboratory courses. ... DeLill Nasser (1929-2000), who was instrumental in promoting genetics ...
Cached Biology News:Chemical analyses uncover secrets of an ancient amphora 2Membrane-coat proteins: Bacteria have them too 2
Request Info...
US Pharmacopoeia Purified-Water/Water-for-Injection Quality Water...
...
... The versatile Zymo-Spin I-96 Plate can ... vacuum manifolds for the large-scale (i.e., 96-well) ... durable polypropylene construction and unique silica-based matrix ... 5 g DNA or RNA in = ...
Biology Products: