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The majority of women (78 percent) who used progesterone suppositories said they leaked. Thirty four percent said the suppositories caused irritation and nearly half found them awkward to administer. A third experienced moderate to very severe side effects.
Most women who took gels and vaginal capsules found them messy and leaky. Of the 11 percent (37 people) who used a progesterone gel, more than three- quarters experienced gel build-up, a common problem with this form. Moderate to very severe side effects occurred with 40 percent of gel users, and one in three (28 percent) women who took progesterone capsules vaginally.
A new progesterone supplement, ENDOMETRIN(R) (progesterone) Vaginal Insert, 100 mg, was recently approved by the U.S. Food and Drug Administration (FDA), giving women the first new progesterone treatment option in a decade. Developed as a more convenient, patient-friendly treatment, ENDOMETRIN tablets are vaginally inserted with a disposable applicator two or three times daily, from the day of oocyte retrieval to about 10 weeks of pregnancy. Results of the largest IVF trial in the world, conducted at 25 U.S. centers in 1,211 women, showed that ENDOMETRIN provides unprecedented support in the final phase of ART treatment, based on high continuing pregnancy and live birth rates.
Research by Ferring Pharmaceuticals, manufacturer of ENDOMETRIN, found
that what patients liked most about ENDOMETRIN is that it is easy to
administer, convenient, painless (no injection), and less messy than
suppositories. Nearly 80 percent would recomme
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| SOURCE Ferring Pharmaceuticals Copyright©2007 PR Newswire. All rights reserved |