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National Survey Shows Most Women Are Not Satisfied With Their Progesterone Treatment
Date:11/12/2007

ar progesterone-in-oil injections typically given by a partner, which can be quite painful. In fact, 69 percent found them painful, 61 percent experienced moderate to very severe side effects, and 71 percent said the injections were inconvenient. Typical descriptions were: "a painful necessary evil," "like injecting yourself with mud," and "Big needle. Shot site can get very sore and expect bruising."

The majority of women (78 percent) who used progesterone suppositories said they leaked. Thirty four percent said the suppositories caused irritation and nearly half found them awkward to administer. A third experienced moderate to very severe side effects.

Most women who took gels and vaginal capsules found them messy and leaky. Of the 11 percent (37 people) who used a progesterone gel, more than three- quarters experienced gel build-up, a common problem with this form. Moderate to very severe side effects occurred with 40 percent of gel users, and one in three (28 percent) women who took progesterone capsules vaginally.

A new progesterone supplement, ENDOMETRIN(R) (progesterone) Vaginal Insert, 100 mg, was recently approved by the U.S. Food and Drug Administration (FDA), giving women the first new progesterone treatment option in a decade. Developed as a more convenient, patient-friendly treatment, ENDOMETRIN tablets are vaginally inserted with a disposable applicator two or three times daily, from the day of oocyte retrieval to about 10 weeks of pregnancy. Results of the largest IVF trial in the world, conducted at 25 U.S. centers in 1,211 women, showed that ENDOMETRIN provides unprecedented support in the final phase of ART treatment, based on high continuing pregnancy and live birth rates.

Research by Ferring Pharmaceuticals, manufacturer of ENDOMETRIN, found that what patients liked most about ENDOMETRIN is that it is easy to administer, convenient, painless (no injection), and less messy than suppositories. Nearly 80 percent would recomme
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SOURCE Ferring Pharmaceuticals
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