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National MS Society Reports Sweeping Advances Made in MS Research in 2012
Date:12/27/2012

and Elan). The test should enhance the ability of people with MS to weigh risks and benefits of this therapy.

Clinical trials discussed at ECTRIMS 2012 – Positive results from trials of statins (cholesterol-reducing medication) and Tysabri in progressive forms of MS, a new approach called AIN457 for treating relapsing MS, and results from phase II and III clinical trials of therapies were among results presented at ECTRIMS focusing on stopping MS. http://www.nationalmssociety.org/news/news-detail/index.aspx?nid=7052

Phase II results of ocrelizumab in relapsing MS – Experimental ocrelizumab (Genentech), given intravenously, significantly reduced disease activity on MRI scans in a study of 218 people with relapsing-remitting MS. One person died due to brain edema; the relation of this death to the medication is unclear. Additional research, now going on in primary-progressive MS and relapsing-remitting MS, is needed to further determine this therapy’s safety and benefits. http://www.nationalmssociety.org/research/research-news/news-detail/index.aspx?nid=5659

Another step toward personalized medicine in MS – Harvard researchers discovered that differences in active genes that are detectable in blood samples may be used to group people with MS into categories that predict disease course and response to therapy. Further research is needed, but it represents an early step toward personalized medicine in MS. http://www.nationalmssociety.org/news/news-detail/index.aspx?nid=6941

New approach to stopping MS – Researchers at Northwestern University have developed an innovative strateg
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