Navigation Links
Nanotechnology in reverse uses cell to calibrate tools
Date:5/15/2008

Nanotechnology researchers at UC Davis have shown that they can use a red blood cell to calibrate a sensitive instrument, an atomic force microscope.

"It turns around the rules of nanotechnology, by using biology to calibrate an instrument," said Volkmar Heinrich, assistant professor in the Department of Biomedical Engineering at UC Davis and co-author of the paper with graduate student Chawin Ounkomol.

An atomic force microscope uses a tiny lever that runs over the surface of an object. Small deflections of the tip are read and translated to produce an image of the object's surface. However, accurate calibration of the springiness of the tip is difficult.

Heinrich and Ounkomol used individual red blood cells sucked onto the end of a pipette to push the lever. The lab has previously developed a model that calculates the exact forces needed to squeeze a red blood cell by a certain amount. They could therefore use the red blood cell to very accurately calibrate the springiness of the atomic force microscope cantilever.

Heinrich does not see the technique as a new way to calibrate these instruments, but it does show that the red blood cell can be used as an accurate force transducer, he said, and could be used as a tool to measure forces between individual molecules and cells or between molecules. Those measurements can advance our understanding of cell biology, for example how cancers spread or how immune cells enter tissues to fight infection.


'/>"/>

Contact: Andy Fell
ahfell@ucdavis.edu
530-752-4533
University of California - Davis
Source:Eurekalert

Page: 1

Related biology technology :

1. Breakthrough in nanotechnology by uncovering conductive property of carbon-based molecules
2. International Council on Nanotechnology launches global research needs assessment
3. Slow federal action to oversee nanotechnology leaves room at the bottom
4. NYU chemist Seeman recognized for founding, establishing the field of structural DNA nanotechnology
5. New nanotechnology television series does sweat the small stuff
6. Religion colors Americans views of nanotechnology
7. National Nanotechnology Initiative releases its fiscal year 2009 budget and highlights
8. Fiber-based nanotechnology in clothing could harvest energy from physical movement
9. New funding to charge energy research at UCL and the London Centre for Nanotechnology
10. Nanotechnology innovation may revolutionize gene detection in a single cell
11. National Nanotechnology Initiative releases new strategic plan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... VALLEY, Calif. , July 31, 2014 ... San Francisco Bay Area , has acquired ... University of Oxford,s commercialisation company. The potent anti-inflammatory activity ... Greaves at the University of Oxford,s Sir ... The company, which has raised over $1.5 million in ...
(Date:7/31/2014)... 31, 2014 Research and Markets ... Market 2014-2018" report to their offering. ... the study of the genetic material or genomes of ... basis for the discovery and development of diagnostic and ... health conditions. Genomics is supported by three major product ...
(Date:7/31/2014)... DIEGO and SHENZHEN, China ... announced today the purchase of an Irys™System ... organization. BGI selected BioNano,s platform to enable comprehensive exploration ... improved assemblies for various organisms of interest, including those ... will partner together to develop new methods for multiplexing ...
(Date:7/31/2014)... (PRWEB) July 31, 2014 Although ... of the first transcriptome-wide analyses appearing around 2008, ... assay for RNA measurement. In the last several ... more specific, work with smaller input amounts, process ... (eg, blood samples). On the bioinformatics side, there ...
Breaking Biology Technology:Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 2Oxford licenses anti-inflammatory peptides to San Francisco Bay Area start-up 3Global Genomics Market 2014-2018: Key Vendors are F. Hoffmann-La Roche, Life Technologies, Qiagen and Illumina 2BioNano Genomics Announces the Purchase of the Irys System by BGI 2BioNano Genomics Announces the Purchase of the Irys System by BGI 3BioNano Genomics Announces the Purchase of the Irys System by BGI 4The Evolution of RNA-Sequencing, Upcoming Live Webinar August 22 hosted by Xtalks 2
... pET vectors for bacterial expression has been the cost ... In order to tackle this problem, DNA2.0 has developed ... free of IP constraints. pJexpress vectors are specifically engineered ... shown to express better than comparable pET vectors. pJexpress ...
... US Oncology, Inc ., one of the nation,s largest cancer care ... Most Admired Companies list for 2009. The company ranks third ... third time US Oncology has been honored with F ... named to the list in 2004 and 2007 in ...
... a leading provider of centralized ECG and eClinical technology, ... and related industries, announced today that it will be ... #1253/1254 at the 21st Annual DIA Euromeeting, 23-25 March ... to three speaking sessions, which will discuss the impact ...
Cached Biology Technology:DNA2.0 Introduces Freedom of Expression With a New Family of Bacterial Expression Vect:ors 2DNA2.0 Introduces Freedom of Expression With a New Family of Bacterial Expression Vect:ors 3US Oncology Named to FORTUNE Magazine's Most Admired Companies List for Third Time 2US Oncology Named to FORTUNE Magazine's Most Admired Companies List for Third Time 3ERT to Showcase Its Clinical Trials Portfolio at DIA's 21st Euromeeting 2ERT to Showcase Its Clinical Trials Portfolio at DIA's 21st Euromeeting 3
(Date:7/31/2014)... Two new meta-analyses involving tree nuts (almonds, Brazil nuts, ... were recently published in the online publications, British ... PLOS ONE (ii). The BMJ Open ... metabolic syndrome (MetS) criteria and showed that tree nut ... fasting blood glucose. The PLOS ONE article ...
(Date:7/30/2014)... Queen in Lewis Carroll,s Through the Looking Glass, ... University of Singapore improved a 35-year-old ecology model ... to millions of years. , The new model, ... the "Red Queen Effect," an evolutionary hypothesis introduced ... suggests that organisms must constantly increase their fitness ...
(Date:7/30/2014)... climate change on the world,s animal and plant ... to a new paper by a research team ... and other organizations. The authors claim that most ... when it comes to climate change. , ... on the "direct" threats of changing temperatures and ...
Breaking Biology News(10 mins):New international tree nut council study looks at nuts, diabetes and metabolic syndrome 2Classic Lewis Carroll character inspires new ecological model 2Classic Lewis Carroll character inspires new ecological model 3Conservation scientists asking wrong questions on climate change impacts on wildlife 2
... Old muscle got a shot of youthful vigor in a ... Berkeley, setting the path for research on new treatments for ... Parkinson,s diseases. In a new study to be published ... Nature , researchers identified two key regulatory pathways that ...
... The University of Delaware has received $400,000 from the ... of an ocean observing system for the Mid-Atlantic region, ... Cod, Mass., and out to the continental shelf. Nearly ... Mid-Atlantic coast. The initiative is part of the ...
... Pep Canadell from CSIRO and the Global Carbon Project, ... billions of tons of carbon dioxide (CO2) absorbed annually ... climate change mitigation worth hundreds of billions of dollars. ... stocks, challenges in quantifying changes in the size of ...
Cached Biology News:Stem cell researchers give old muscle new pep 2Stem cell researchers give old muscle new pep 3Stem cell researchers give old muscle new pep 4UD nets NOAA funding for Mid-Atlantic ocean observing 2Tropical forest sustainability: A climate change boon 2
... Detection Platform combines robust chemistry with ... sensitive, specific, and cost-effective detection method ... Platform offers exceptional performance with specificity ... high signal/background ratio, and an expanded ...
Request Info...
... Gel Band Purification Kit, 100. For the purification, ... fragments (0.1-10 kb) from solution and from TAE ... from solution in as little as 5 min ... min.Prepacked glass fiber matrix columns provide consistent results ...
BD BaculoGold Max-XP Insect Cell Medium 1 Liter...
Biology Products: