Navigation Links
Nanotech particles affect brain development in mice
Date:7/28/2009

Maternal exposure to nanoparticles of titanium dioxide (TiO2) affects the expression of genes related to the central nervous system in developing mice. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology found that mice whose mothers were injected with the nanoparticles while pregnant showed alteration in gene expression related to neurological dysfunction.

Ken Takeda led a team of researchers from the Tokyo University of Science, Japan, who carried out the tests. He said, "Nanotechnology and the production of novel man-made nanoparticles are increasing worldwide. Titanium dioxide in its nanoparticle form has a high level of photocatalytic activity, and can be used for air and water purification and self-cleaning surfaces. Our findings, however, add to the current concern that this specific nanomaterial may have the potential to affect human health".

For this study, the researchers injected pregnant mice with Ti02 nanoparticles. The brains were obtained from male fetuses/pups on the 16th day of gestation and at several points after birth. Comparing these brains to those of control animals, the researchers were able to demonstrate changes in expression of hundreds of genes. According to Takeda, "Diseases associated with these genes include those we normally consider to develop in childhood, such as autistic disorder, epilepsy and learning disorders, and also others that arise mainly in adulthood or old age, such as Alzheimer's disease, schizophrenia and Parkinson's disease."

Nanotechnology deals with engineering at the molecular scale. Materials reduced to nanoparticles behave in ways dissimilar to those we're used to - altering their reactivity, surface area to volume and any number of other properties. While larger TiO2 particles are commonly used in paints and sunblocks, nanoparticles of TiO2 are specially created for new applications in coatings and self-cleaning surfaces and their effe
'/>"/>

Contact: Graeme Baldwin
graeme.baldwin@biomedcentral.com
44-020-319-22165
BioMed Central
Source:Eurekalert

Page: 1 2

Related biology technology :

1. New statistical technique improves precision of nanotechnology data
2. Particle Sciences and Microfluidics Collaborate to Share Formulation and Nanotechnology Expertise for Pharmaceutical Drug Product Development, Analysis and Commercialization
3. Dozens of New Clean Technology and Nanotech Products Unveiled at TechConnect World Expo in Houston, Texas, May 5-6
4. Novel CU-Boulder technique shrinks size of nanotechnology circuitry
5. Quest PharmaTech Announces Strategic Alliance with IntelligentNano to Develop Nanotechnology-Based Next Generation SL052
6. Advance Nanotechs Owlstone Announces First Pharmaceutical Industry Order
7. Nanotechnology: Will it drive a new innovation economy for the US?
8. Nanotechnologists gain powerful new materials probe
9. Nanotechnology makes supertelescopes much more sensitive
10. Worlds first mandatory national nanotech rule pending
11. Ethical evaluations of nanotechnology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/29/2014)... 2014 Each year in the ... medical attention. In the military, burn injury is ... battlefield medical care. More than 800 service members ... wounds heal slowly, remain inflamed and often become ... debilitating and functionally damaging. While developments in supportive ...
(Date:9/29/2014)... start of the military conflicts in Iraq and Afghanistan, ... States with traumatic brain injury caused by exposure to ... explosive devices, or IEDs. Symptoms of traumatic brain injury ... and nausea, to more severe impairments in memory and ... Defense has recognized the critical importance and complexity of ...
(Date:9/29/2014)... Research and Markets  has announced the ... & Services, End-User , Application - Global Forecast to ... The global oligonucleotide synthesis market is expected to reach ... growing at a CAGR of 9.8% from 2014 to ... the basis of products and services, applications, end users, ...
(Date:9/29/2014)... diseases and biodiversity loss requires evolutionary thinking, argues ... Express that was co-authored by Bruce Tabashnik ... and Life Sciences. , For the first time, ... progress in addressing a broad set of challenges ... that consider evolutionary histories and the likelihood of ...
Breaking Biology Technology:Faster Healing with Fewer Scars 2Modeling shockwaves through the brain 2Modeling shockwaves through the brain 3Modeling shockwaves through the brain 4Oligonucleotide Synthesis (Diagnostics, PCR, QPCR, Gene Synthesis, NGS, DNA, RNAi) Market - Global Forecast to 2019 2Oligonucleotide Synthesis (Diagnostics, PCR, QPCR, Gene Synthesis, NGS, DNA, RNAi) Market - Global Forecast to 2019 3Evolutionary biology: It's not just for textbooks anymore 2Evolutionary biology: It's not just for textbooks anymore 3
... Iceland, Jan. 4 deCODE genetics,(Nasdaq: DCGN ) ... of deCODE,CEO Kari Stefansson,s presentation at the JPMorgan 26th ... 11:30 am PST / 7:30 pm GMT on,Thursday, January ... webcast can be accessed through the Investors page on ...
... to study technology to reduce greenhouse gas emissions, ... Midland,Company (NYSE: ADM ), the Midwest Geological ... (ISGS) announce that they are,working together on a ... and storage of carbon dioxide from ADM,s ethanol ...
... development programs, including review of positive results from the Phase ... ... Jan. 4 QuatRx Pharmaceuticals Company,today announced that the company chief ... 26th Annual JP Morgan Healthcare,Conference on Tuesday, January 8th, 2008, at ...
Cached Biology Technology:ADM, MGSC and ISGS Announce Carbon Sequestration Project 2ADM, MGSC and ISGS Announce Carbon Sequestration Project 3QuatRx Pharmaceuticals to Present at 26th Annual JP Morgan Healthcare Conference 2
(Date:9/29/2014)... Genome Institute (DOE JGI), a DOE Office of ... projects have been selected for the 2015 Community ... Caribbean waters, and from plant root micro-ecosystems, to ... watersheds, the CSP 2015 projects portfolio highlights diverse ... , "These projects catalyze JGI,s strategic shift ...
(Date:9/29/2014)... The BRAF inhibitor dabrafenib has significant anti-tumour activity ... cell lung cancer whose disease has progressed after ... the ESMO 2014 Congress in Madrid, Spain. ... BRAF have generated considerable interest because these mutations ... tyrosine-kinase inhibiting agents," says lead author Dr David ...
(Date:9/29/2014)... Oktoberfest is here, and that means ... for a cold one, taking that first ... chemicals have reacted to form compounds that ... Reactions explains why beers get skunky, and ... brews from going bad. Learn all about ...
Breaking Biology News(10 mins):2015 DOE JGI's science portfolio delves deeper into the Earth's data mine 22015 DOE JGI's science portfolio delves deeper into the Earth's data mine 32015 DOE JGI's science portfolio delves deeper into the Earth's data mine 42015 DOE JGI's science portfolio delves deeper into the Earth's data mine 52015 DOE JGI's science portfolio delves deeper into the Earth's data mine 62015 DOE JGI's science portfolio delves deeper into the Earth's data mine 72015 DOE JGI's science portfolio delves deeper into the Earth's data mine 82015 DOE JGI's science portfolio delves deeper into the Earth's data mine 9Promising results shown with targeted approaches in subsets of non-small cell lung cancer 2Promising results shown with targeted approaches in subsets of non-small cell lung cancer 3
... along the Mississippi River and other areas are altering ... a researcher from Iowa State University. Fred Janzen, ... studied turtle nesting habits and also accumulated research going ... the turtles to find out when they make nests ...
... snakes may slither in saltwater, but they sip the ... zoologist in a paper appearing this month in the ... Physiological and Biochemical Zoology . Harvey Lillywhite ... roughly 60 species of venomous sea snakes worldwide satisfy ...
... incoming administration will confront an array of threats and ... American president, says Steve Fetter, dean of the University ... won, Fetter asked six experts on his faculty with ... recommending steps to address key challenges. Most ...
Cached Biology News:Turtles alter nesting dates due to temperature change says ISU researcher 2Zoologists: Sea snakes seek out freshwater to slake thirst 2Zoologists: Sea snakes seek out freshwater to slake thirst 3Advice to the new administration: UM foreign and domestic policy guide 2Advice to the new administration: UM foreign and domestic policy guide 3Advice to the new administration: UM foreign and domestic policy guide 4Advice to the new administration: UM foreign and domestic policy guide 5Advice to the new administration: UM foreign and domestic policy guide 6Advice to the new administration: UM foreign and domestic policy guide 7