Navigation Links
Nanoscale dimensioning is fast, cheap with new NIST optical technique
Date:10/29/2008

A novel technique* under development at the National Institute of Standards and Technology (NIST) uses a relatively inexpensive optical microscope to quickly and cheaply analyze nanoscale dimensions with nanoscale measurement sensitivity. Termed Through-focus Scanning Optical Microscope (TSOM) imaging, the technique has potential applications in nanomanufacturing, semiconductor process control and biotechnology.

Optical microscopes are not widely considered for checking nanoscale (below 100 nanometers) dimensions because of the limitation imposed by wavelength of lightyou cant get a precise image with a probe three times the objects size. NIST researcher Ravikiran Attota gets around this, paradoxically, by considering lots of bad (out-of-focus) images. This imaging uses a set of blurry, out-of-focus optical images for nanometer dimensional measurement sensitivity, he says. Instead of repeatedly focusing on a sample to acquire one best image, the new technique captures a series of images with an optical microscope at different focal positions and stacks them one on top of the other to create the TSOM image. A computer program Attota developed analyzes the image.

While Attota believes this simple technique can be used in a variety of applications, he has worked with two. The TSOM image can compare two nanoscale objects such as silicon lines on an integrated circuit. The software subtracts one image from the other. This enables sensitivity to dimensional differences at the nanoscaleline height, width or side-wall angle. Each type of difference generates a distinct signal.

TSOM has also been theoretically evaluated in another quality control application. Medical researchers are studying the use of gold nanoparticles to deliver advanced pharmaceuticals to specific locations within the human body. Perfect size will be critical. To address this application, a TSOM image of a gold nanoparticle can be taken and compared to a library of sim
'/>"/>

Contact: Evelyn Brown
evelyn.brown@nist.gov
301-975-5661
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Nanoscale carbon materials research wins the 2008 Julius Springer Prize for Applied Physics
2. New nanoscale process created by UCSB scientists will help computers run faster and more efficiently
3. Nanoscale silver: No silver lining?
4. BioNanomatrix Awarded New NIH Grant for Development of Nanoscale Platform for Single-Molecule DNA Mapping and Haplotype Applications
5. Penn researchers demonstrate a flexible, 1-step assembly of nanoscale structures
6. University of Pennsylvania engineers reveal what makes diamonds slippery at the nanoscale
7. A look into the nanoscale
8. Trap and zap: Harnessing the power of light to pattern surfaces on the nanoscale
9. Engineers whip up the first long-lived nanoscale bubbles
10. Physicists discover gold can be magnetic on the nanoscale
11. Surface dislocation nucleation: Strength is but skin deep at the nanoscale, Penn engineers discover
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nanoscale dimensioning is fast, cheap with new NIST optical technique
(Date:3/5/2015)... March 05, 2015 Bi-Biomics today ... paraffin and stain additive. The improvement in histological ... binary features present in all daughter cells. , ... chromatin packaging was analyzed at 1000-1600x using light ... chromatin patterning in all daughter cells displayed predominant ...
(Date:3/5/2015)... 05, 2015 Research and Markets ( ... "Mature Biotech Outlook 2015: New Therapy Ventures Pave the ... All biotech companies - Gilead (GILD), Amgen ... year, have given a positive return and hence increased ... able to select therapy/niche indication where the high treatment ...
(Date:3/5/2015)... RMI specializes in Stemnexa™ ... such as meniscal tears, ACL injuries, rotator cuff ... due to degenerative conditions like osteoarthritis. Stemnexa ... promote better post-surgical outcomes. , Stemnexa combines the ... marrow harvesting with two complimentary cellular technologies: Bone ...
(Date:3/4/2015)... BROOKLYN, N.Y. , March 4, 2015  Brooklyn ... treat their acute and chronic pain and injuries. ... to announce the grand opening of his NJS Physical ... NY on Thursday, March 5, 2015. Health ... the facility, which is located at 1178 Flatbush Avenue. ...
Breaking Biology Technology:Mature Biotech Outlook 2015: New Therapy Ventures Pave the Way for Success 2Mature Biotech Outlook 2015: New Therapy Ventures Pave the Way for Success 3Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 2Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 3Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 4Riordan-McKenna Institute of Regenerative Orthopedics and Stem Cell Therapy Announces Open House in Southlake, Texas on Friday, March 6th from 5:30 pm to 7:30 pm. 5NJS Physical Medicine & Rehabilitation Opening on Flatbush Avenue, Brooklyn, NY 2
... Powerful technology from Varian Medical Systems and BrainLAB enabling, non-invasive ... ... system, PALO ALTO, Calif., and WESTCHESTER, ... the use of stereotactic body radiosurgery (SBRT) for the treatment,of cancer and ...
... Breast Cancer, PARSIPPANY, N.J., Sept. 22 Who ... your teens and your 50s could increase your risk,of ... out about the,link between excess weight and breast cancer, ... and improve their health, but to also help,deal with ...
... Our brain consists of billions of cells that ... − which enables us to learn, remember, and so ... make contact correctly, or, in other words, when there ... process is a controlled protein production along with the ...
Cached Biology Technology:Non-Invasive Radiosurgery with Novalis Tx(TM) Platform Rolling Out Worldwide 2Non-Invasive Radiosurgery with Novalis Tx(TM) Platform Rolling Out Worldwide 3Non-Invasive Radiosurgery with Novalis Tx(TM) Platform Rolling Out Worldwide 4Non-Invasive Radiosurgery with Novalis Tx(TM) Platform Rolling Out Worldwide 5alli(TM) Partners with Breast Cancer Network of Strength(TM) to Support Women Challenged by Breast Cancer, Weight Loss or Both 2alli(TM) Partners with Breast Cancer Network of Strength(TM) to Support Women Challenged by Breast Cancer, Weight Loss or Both 3Revealing the regulating mechanism behind signal transduction in the brain 2
(Date:2/5/2015)... MOUNTAIN VIEW, Calif. , Feb. 3, 2015 ... screen printer technology, demand from industries such as ... the global market for surface mount technology (SMT) ... manual equipment to automatic control will push the ... glue dispensers will remain steady as glue dispensers ...
(Date:1/22/2015)... Jan. 13, 2015 /PRNewswire/ - Today, FindBiometrics, the leading source of ... of its new website design. "When we launched ... says Peter O,Neill , founder and CEO of FindBiometrics. ... needs involvement from the key players on a very broad ...
(Date:1/22/2015)... , Jan. 15, 2015  BellBrook Labs, a leader ... announced the launch of a TR-FRET (time resolved ... Transcreener UDP Assay, a high throughput screening assay ... assay will allow for sensitive detection of hundreds ...
Breaking Biology News(10 mins):End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 2End-user Demand Spurs Global SMT Screen Printers and Glue Dispensers Market 3Identity Industry Leading Publication Debuts New Look As Biometrics Hit Mainstream 2BellBrook Labs Launches a High Throughput Screening Assay for Glycosyltransferases with TR-FRET Readout 2
... DIEGO (July 15, 2012) Despite ongoing public ... the food supply, annually causing significant sickness and death throughout ... ground. In a major finding, published today in the ... Institute for Allergy & Immunology have discovered a molecule,s previously ...
... be cautious in setting new ,low-carbon, standards for greenhouse ... fuels from conventional crude oils University of Calgary and ... in the journal Environmental Science & Technology . ... data from actual oil sands operations, did a ,well-to-wheel, ...
... new study by University of North Carolina School of Medicine ... risk for autism spectrum disorders (ASD) at 12 months received ... In addition, 85 percent of the children found to be ... Year Inventory (FYI), a 63-item questionnaire filled out by their ...
Cached Biology News:La Jolla institute identifies critical cell in fighting E. coli infection 2La Jolla institute identifies critical cell in fighting E. coli infection 3Caution needed with new greenhouse gas emission standards 2Questionnaire completed by parents may help identify 1-year-olds at risk for autism 2
Borosilicate Glass. Certified for use with the Beacon 2000 Systems, 1,000 tubes/case...
Whole blood is collected from mice (Swiss Webster, 8-10 weeks old,either sex) and processed within 45 minutes of collection. The complement is then filtered and pooled on ice, bottled and stored at -...
... new technology incorporating the sophisticated DirectDrive ... the new Varian NMR System is ... today., ,The Varian NMR System features ... receiver channel, providing pulse sequence programming ...
... Immunogen : Recombinant human HMGN2/HMG-17 ... BSA, 0.15M NaCl, 0.05% sodium ... glycerol to 30% Quality Assurance: ... acid extracts of murine 10T ...
Biology Products: