Navigation Links
Nanoscale dimensioning is fast, cheap with new NIST optical technique
Date:10/29/2008

A novel technique* under development at the National Institute of Standards and Technology (NIST) uses a relatively inexpensive optical microscope to quickly and cheaply analyze nanoscale dimensions with nanoscale measurement sensitivity. Termed Through-focus Scanning Optical Microscope (TSOM) imaging, the technique has potential applications in nanomanufacturing, semiconductor process control and biotechnology.

Optical microscopes are not widely considered for checking nanoscale (below 100 nanometers) dimensions because of the limitation imposed by wavelength of lightyou cant get a precise image with a probe three times the objects size. NIST researcher Ravikiran Attota gets around this, paradoxically, by considering lots of bad (out-of-focus) images. This imaging uses a set of blurry, out-of-focus optical images for nanometer dimensional measurement sensitivity, he says. Instead of repeatedly focusing on a sample to acquire one best image, the new technique captures a series of images with an optical microscope at different focal positions and stacks them one on top of the other to create the TSOM image. A computer program Attota developed analyzes the image.

While Attota believes this simple technique can be used in a variety of applications, he has worked with two. The TSOM image can compare two nanoscale objects such as silicon lines on an integrated circuit. The software subtracts one image from the other. This enables sensitivity to dimensional differences at the nanoscaleline height, width or side-wall angle. Each type of difference generates a distinct signal.

TSOM has also been theoretically evaluated in another quality control application. Medical researchers are studying the use of gold nanoparticles to deliver advanced pharmaceuticals to specific locations within the human body. Perfect size will be critical. To address this application, a TSOM image of a gold nanoparticle can be taken and compared to a library of sim
'/>"/>

Contact: Evelyn Brown
evelyn.brown@nist.gov
301-975-5661
National Institute of Standards and Technology (NIST)
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Nanoscale carbon materials research wins the 2008 Julius Springer Prize for Applied Physics
2. New nanoscale process created by UCSB scientists will help computers run faster and more efficiently
3. Nanoscale silver: No silver lining?
4. BioNanomatrix Awarded New NIH Grant for Development of Nanoscale Platform for Single-Molecule DNA Mapping and Haplotype Applications
5. Penn researchers demonstrate a flexible, 1-step assembly of nanoscale structures
6. University of Pennsylvania engineers reveal what makes diamonds slippery at the nanoscale
7. A look into the nanoscale
8. Trap and zap: Harnessing the power of light to pattern surfaces on the nanoscale
9. Engineers whip up the first long-lived nanoscale bubbles
10. Physicists discover gold can be magnetic on the nanoscale
11. Surface dislocation nucleation: Strength is but skin deep at the nanoscale, Penn engineers discover
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Nanoscale dimensioning is fast, cheap with new NIST optical technique
(Date:8/28/2014)... Aug. 28, 2014  Next month, executives from clinical trial ... industry events beginning with Patient-Centered Clinical Trials 2014 , ... Boston , September 4-5. Patient recruitment experts ... Aaron Fleishman will share insights on the benefits of ... of tactics – from media to mobile apps – can ...
(Date:8/28/2014)... August 28, 2014 Sterlitech is proud ... membranes to its stable of products . ... weight cut-offs and include membrane filters with surface charges. ... in customer demand for our membrane process testing equipment, ... of flat sheet membranes,” explains Sterlitech President Mark Spatz. ...
(Date:8/28/2014)... new work by a Florida State University research team ... take your temperature, emit white light, and convert photon ... looks like a butterfly. , Biwu Ma, associate professor ... the FAMU-FSU College of Engineering, created the molecule in ... to discover that his creation has many other unique ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 A ... around the world is available from Strategic Consulting, ... companies. “ Industrial Microbiology Market Review, Fourth Edition: ... Market ” (IMMR—4) tracks and compares microbiology test ... North America, Europe and Asia, and forecasts future ...
Breaking Biology Technology:BBK Worldwide Leads Sessions at Key September Events 2Sterlitech Corporation Enhances Its Selection of Flat Sheet Membrane Filters 2Novel 'butterfly' molecule could build new sensors, photoenergy conversion devices 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 22 Billion Industrial Microbiology Tests Conducted for Product Quality and Safety Worldwide 3
... 15, 2011 Amsterdam Molecular Therapeutics (Euronext: AMT), ... today that the Company has a negative equity position, as ... negative equity position is in line with previous guidance that ... alternatives for additional financing. AMT announced on November ...
... 2011 National Ergonomics Conference and Exposition (ErgoExpo) held at Caesars ... largest annual gathering of ergonomics decision makers and vendors in ... the last few hours of the show, the room still ... renewed and new exhibitors had signed up for 2012.  ...
... December 14, 2011 Elsevier, a world-leading ... services, and the Federation of Biochemical Societies (FEBS) announced ... an open access journal. The journal is dedicated to ... in both health and disease. , ,In launching this ...
Cached Biology Technology:Amsterdam Molecular Therapeutics Announces Negative Equity Position 2Amsterdam Molecular Therapeutics Announces Negative Equity Position 32011 ErgoExpo Attendees' Choice Award Winners Announced During Sold Out Expo; Exhibitor Renewal for 2012 Hits 96% and Counting 22011 ErgoExpo Attendees' Choice Award Winners Announced During Sold Out Expo; Exhibitor Renewal for 2012 Hits 96% and Counting 3Elsevier and Federation of Biochemical Societies Launch New Journal: FEBS Open Bio 2Elsevier and Federation of Biochemical Societies Launch New Journal: FEBS Open Bio 3
(Date:8/29/2014)... of marine phytoplankton, such as the prolific bloomer ... (thiamine), researchers have discovered. The finding contradicts the common ... eukaryotic microbes depend on scarce supplies of thiamine in ... way to think about the ocean," says CIFAR Senior ... ISME Journal paper with CIFAR fellows John ...
(Date:8/28/2014)... now available from the Lady Bird Johnson Wildflower Center ... harmful non-native plant, insect and other invasive species statewide. ... about $137 billion in economic and other damage annually ... plants and more. , "By having streamlined tools like ... occur, we,re more likely to catch these threats early ...
(Date:8/28/2014)... is available in German . ... owes its name to a striking pattern of blue stripes ... cells, reflective silvery cells, and yellow cells emerge during growth ... as a multilayered mosaic to compose the characteristic colour pattern. ... types have to interact to form proper stripes, the embryonic ...
Breaking Biology News(10 mins):Not all phytoplankton in the ocean need to take their vitamins 2Not all phytoplankton in the ocean need to take their vitamins 3Mobile app makes ID of harmful plants, insects in Texas a snap 2How the zebrafish gets its stripes 2How the zebrafish gets its stripes 3
... complex analysis of protein interactions, researchers from IRB Barcelona ... mechanisms that may be involved in the development of ... cell biologists, was led by IRB Barcelona group leader ... the Genome Research , a reference journal in ...
... View, Calif. -- 23andMe has launched a project funded ... aimed at validating 23andMe,s highly-scalable platform for pharmacogenomics research. ... American Recovery and Reinvestment Act of 2009 for "Web-based ... NIH,s National Human Genome Research Institute. ...
... French . A mother,s voice will preferentially activate the ... researchers from the University of Montreal and the Sainte-Justine ... discovery after performing electrical recordings on the infants within ... also revealed that while the infants did react to ...
Cached Biology News:Scientists identify the largest network of protein interactions related to Alzheimer's disease 223andMe receives NIH funding to evaluate web-based research on the genetics of drug response 2Allô allô! Mom's voice plays special role in activating newborn's brain 2
Goat polyclonal to CHMP5 ( Abpromise for all tested applications). Antigen: Synthetic peptide: C-NKDGVLVDEFGLPQ, corresponding to C terminal amino acids 202-215 of Human CHMP5 Entrez GeneID: ...
Rabbit polyclonal to Reptin/TIP49B/RUVB2 ( Abpromise for all tested applications). Antigen: Synthetic peptide (Human) Entrez Gene ID: 10856 Swiss Protein ID: Q6FIB9...
Goat polyclonal to ORC2L ( Abpromise for all tested applications). entrezGeneID: 4999 SwissProtID: Q13416...
14-3-3 tau Antibody Shipping Temperature: HOT Storage Temperature: -20C...
Biology Products: