Navigation Links
Nanomedical Diagnostics Launches New Agile Biosensor to Accelerate Label-free Drug Development
Date:8/15/2017

Nanomedical Diagnostics, a cutting-edge life science company pioneering graphene biosensors that accelerate pharmaceutical and biotherapeutics development, announces the launch of the new NHS Agile biosensor chip. The new chip reduces the number of steps needed to gain kinetic binding data for a wide range of molecules, including small and large molecules, peptides, proteins, and antibodies. NHS biosensors are designed for use on the company’s Agile R100 label-free personal assay system which has an unprecedented 11-log dynamic range, making it possible to develop weakly-binding fragments into high-affinity compounds with a single platform.

“Many pharmaceutical companies have established protocols for studying molecules using standard amine-linker chemistry,” noted Nanomedical Diagnostics CEO, Ross Bundy. “However, traditional methods using these protocols require numerous steps on complicated machines that make experiments difficult to run and prone to variability. Our new NHS biosensor combined with the single-sample format Agile R100 allows researchers to leverage these tried and true techniques, but reduces the process greatly compared to prior systems. Both experiment complexity and results variability are decreased, which gives all researchers the ability to gain reliable label-free kinetic binding data for their molecules at their benchtop, on their schedule.”

Agile R100 is the first kinetic characterization platform built with proprietary Field Effect Biosensing (FEB) technology, a breakthrough electrical technique for measuring biomolecular interactions in real-time. Unlike SPR- and BLI-based assays which have a limited ability to sense in complex samples, FEB measures changes in conductance instead of mass and is unaffected by solvents or detergents that interfere with optical readings. This provides researchers access to the first truly novel label-free technique in decades.

The NHS Agile Biosensor Chip has pre-activated amine-linker chemistry that enables rapid immobilization of any molecule with a free amine group, allowing for flexible, fast kinetic characterization using a wide range of target classes. Like all Agile biosensors, the NHS chips provide up to 10 measurements with just 10 µL drops of sample, enabling entire dose-response curves to be run with one chip, increasing cost-efficiency. Agile R100’s single-sample format lets researchers apply sample directly to the sensor surface, making the platform easy to run with little training.

“The NHS biosensor chip is the second chemistry released by the company in two months,” continues Mr. Bundy. “We’re expanding the Agile R100 system menu quickly to meet the pressing need in drug discovery for an easy-to-use detection technique that can sense in complex samples, enabling a large reduction in background noise and accurate, reproducible kinetic measurements.”

About Nanomedical Diagnostics
Nanomedical Diagnostics (“Nanomed”) is a life science company based in San Diego, CA. Nanomed has developed a breakthrough electrical assay based on proprietary Field Effect Biosensing (FEB) technology that delivers real-time label-free kinetic binding and affinity data. Unique graphene biosensors at the heart of the assay provide highly-sensitive kinetic characterization of small molecules and proteins in complex solutions from solvents and detergents to cell fractions and tissue lysate. Using just a 10 µL drop of sample, the platform is a cutting-edge orthogonal technique for drug discovery hit validation.

Read the full story at http://www.prweb.com/releases/Nanomedical_Diagnostics/NHS_Biosensor_Launch/prweb14596031.htm.


'/>"/>
Source: PRWeb
Copyright©2017 Vocus, Inc.
All rights reserved


Related biology technology :

1. Nanomedical Diagnostics Launches New Biosensor for Label-free Kinetic Binding Analysis of Proteins
2. Nanomedical Diagnostics Issued Key Patent for AGILE R100, a Graphene Biosensor for Drug Discovery
3. Nanomedical Diagnostics VP Production to Speak at Materials Research Society Spring Meeting
4. Nanomedical Diagnostics Announces Partnership with Rogue Valley Microdevices, Delivering World’s First Successful High-Volume Manufacturing for Graphene Biosensors
5. Nanomedical Diagnostics to Present Field Effect Biosensing for Fragment-Based Drug Discovery at SLAS 2017
6. Nanomedical Diagnostics CEO and CTO to Introduce Electronic Label-Free Assay Based on Field Effect Biosensing Technology at IDTechEx Show
7. Nanomedical Diagnostics launches a new graphene biosensor with unprecedented functionality for small molecule and protein analysis
8. Nanomedical Diagnostics Announces Scientific Advisory Board of Top Scientists and Medical Researchers
9. Global Lyme Diagnostics Welcomes Dr. Mark Filidei and Dr. Jodie A. Dashore To Scientific Advisory Board
10. CNA Finance Initiates Research Coverage On Interpace Diagnostics
11. Co-Diagnostics, Inc. to Use IPO Proceeds to Expand Operations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/10/2017)... ... 2017 , ... San Diego-based team building and cooking events company, Lajollacooks4u, has ... The bold new look is part of a transformation to increase awareness, appeal to ... period. , It will also expand its service offering from its signature gourmet cooking ...
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/9/2017)... DIEGO , Oct. 9, 2017  BioTech ... biological mechanism by which its ProCell stem cell ... critical limb ischemia.  The Company, demonstrated that treatment ... amount of limbs saved as compared to standard ... the molecule HGF resulted in reduction of therapeutic ...
Breaking Biology Technology:
(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... 24, 2017 The Controller General of Immigration from ... Abdulla Algeen have received the prestigious international IAIR Award for the ... Continue Reading ... ... Controller Abdulla Algeen (small picture on the right) have received the IAIR ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based ... to 2022", published by MarketsandMarkets, the market is expected to be worth USD ... 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):