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Nanocopoeia Licenses New Polymer-Based Biomaterials Platform From the University of Western Ontario
Date:6/26/2008

Follows the launch of their first partnership venture, NanoInterventions,

at BIO International

ST. PAUL, Minn. and LONDON, Ontario, June 26 /PRNewswire/ -- Following the launch at BIO International in San Diego last week of NanoInterventions, their cardiovascular joint venture partnership, Nanocopoeia and WORLDiscoveries(TM) are pleased to announce their broader agreement to co-develop the biomedical uses of arborescent polyisobutylene-based block copolymers. Nanocopoeia, a drug delivery company specializing in therapeutic coatings for medical devices, will lead the development effort and WORLDiscoveries(TM) will participate as a partner in the market-targeted applications. The agreement includes an exclusive world-wide license, for all biomedical fields of use, for the polymer system that is the subject of US Patent No. 6,747,098 (2004) and nine other international issued patents.

Arborescent polyisobutylene-based block copolymers are branched polymers with unique properties for biomedical use. A major market opportunity is their use as a drug-eluting coating for medical devices such as coronary stents. When applied using Nanocopoeia's proprietary ElectroNanospray(TM) process, the polymer provides a highly controllable matrix for drug delivery and has excellent physical properties. For other applications, such as tissue implants, this family of polymers has many attributes in common with silicone materials but without the need of the additional chemicals that are required to formulate silicone-based devices.

Judit E. Puskas, PhD, P.Eng, led the team at Western that invented the family of polymers based on arborescent polyisobutylene. She held the Bayer/NSERC (Natural Science and Engineering Research Council of Canada) Industrial Research Chair at Western between 1998 and 2003, and is now Professor of Polymer Science at The University of Akron in Ohio. Dr. Puskas commented, "This polymer system has enormous flex
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