Navigation Links
Nanobiotechnology experts join forces to improve TB testing
Date:9/27/2010

Two UK companies have been awarded joint funding for a research project that could see significant advances in the quest to aid detection and eradication of Tuberculosis (TB), across the world.

The National Physical Laboratory (NPL) and Orla Protein Technologies (Orla) have been awarded 91,000 by the Technology Strategy Board to investigate improved methods for the detection of TB.

The project, which begins in this month, involves a combination of cutting edge technologies and expertise based here in the UK, including areas of molecular and biological diagnostics (Orla), and measurement science and infectious diseases (NPL).

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of almost all cases if tuberculosis.

More than five thousand people die every day from TB, largely in the developing world. TB is one of the major lethal factors among AIDS patients. Largely, TB affects the developing world where the situation is worsened with the infection becoming one of the main lethal factors among HIV-infected individuals.

Current methods of TB detection suffer from a need for large sample volumes, long preparation times and different results from different patient groups. This has led to a demand for more sensitive and rapid approaches to be developed.

The Consortium aims to meet this demand, by producing systems which dramatically advance current methods; helping to improve the sensitivity, specificity, cost and speed of results.

Max Ryadnov, Project Leader at NPL, said: "The main objective of the project is to demonstrate the possibility of detecting MTB quickly and cost effectively in both clinical and near-patient settings. Such capability is a Holy Grail of modern diagnostics of MTB and would significantly impact on the UK and global healthcare markets."

The study will make use of techniques developed at the National Physical Laboratory for the detection of MTB antigens - biomarkers which indicate disease to rapidly assess the presence of the MTB in a sample. These techniques are empowered by a unique technology developed by Orla PT allowing the fabrication of protein patterned surfaces responsive to MTB biomarkers thereby making the manufacture and use of biomarker detection dramatically simpler"

Dale Athey, Chief Executive at Orla, said: "The development of such procedures will help to substantially improve health systems in resource-limiting settings, particularly in HIV-infected TB cases, where sensitivity remains well below confidence limits for all MTB tests.

"We hope the project will allow us to significantly improve consistency and enhanced sensitivity for cost-effective, easy to use point-of-care-solutions for the detection and eradication of MTB."

The project team will also work closely with colleagues in the Health Protection Agency for advice on microbiology, and to arrange testing in a clinical environment.


'/>"/>

Contact: David Lewis
david@proofcommunication.com
084-568-01865
National Physical Laboratory
Source:Eurekalert

Related biology technology :

1. Global Nanobiotechnology Market to Reach $4.94 Billion by 2015, According to New Report by Global Industry Analysts, Inc.
2. SU research team uses nanobiotechnology-manipulated light particles to accelerate algae growth
3. USP's 2008 Annual Scientific Meeting to Convene Scientific Experts from Around the World
4. Celebrity Designer Ty Pennington to Host 10th Annual ADHD Experts on Call Program
5. Health Experts Call for New Strategies to Combat Alarming Rise in Diabetes
6. Genstruct Added to The Biomarker Consortiums Rapidly Growing Roster of Industry Experts
7. MaxCyte Hosts Live Discussion with Industry Experts on the Challenges in Developing Cell-Based Screening Assays for Drug Discovery
8. BioFlorida Selects Collexis BiomedExperts.com as the Primary Professional Network for its 200 Member Companies and Organizations
9. Top LASIK and Refractive Experts in Trusted LASIK Surgeons Directory Present Research and Educate Their Peers at Annual AAO Meeting in Atlanta
10. Experts argue nano food-additives require new oversight
11. African Ancestry, Educators, Identity Experts Launch DNA Education Project during Historic Black History Month; 7th Graders Score High on Ultimate Self Test
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... , March 28, 2017 /PRNewswire/ -RepliCel Life Sciences Inc. ... pleased to report compelling safety and clinical data from its ... type 1 collagen-expressing, hair follicle-derived fibroblasts (RCT-01) as a treatment ... ... establishing a complete safety profile at 6 months and showed ...
(Date:3/28/2017)... ... March 28, 2017 , ... Executive search ... with Avomeen Analytical Services. Harvill is a distinguished life sciences expert with a ... is a leader in a wide range of services related to laboratory testing ...
(Date:3/27/2017)... ... March 27, 2017 , ... IsoPlexis Corporation (IsoPlexis), a ... disease and more through a single-cell precision engineering platform, today announced it has ... in the laboratory of Dr. James Heath at the California Institute of ...
(Date:3/27/2017)... (PRWEB) , ... March 27, 2017 , ... ... cancer (mCRC) generally produce small, heterogeneous samples with limited tumor content in a ... remain to be resolved, such as the need for reliable detection of low ...
Breaking Biology Technology:
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based and ... 2022", published by MarketsandMarkets, the market is expected to be worth USD 18.98 ... Continue Reading ... ...      ...
(Date:3/20/2017)... HANOVER, Germany , March 20, 2017 At ... Hamburg -based biometrics manufacturer DERMALOG. The Chancellor came to the ... Japan is this year,s CeBIT partner country. At the largest ... important biometrics in use: fingerprint, face and iris recognition as well as ... ...
(Date:3/9/2017)... MOUNTAIN VIEW, Calif. , March 9, 2017 ... and 23andMe , the leading personal genetics company, ... Zipongo can now provide customers with personalized nutrition plans ... and biometrics, but also genetic markers impacting how their ... Zipongo,s personalized food decision support platform uses biometrics such ...
Breaking Biology News(10 mins):