Navigation Links
NLST data highlight probability of lung cancer overdiagnosis with low-dose CT screening
Date:12/9/2013

ung cancer (all types and stages) detected by screening with LDCT is an overdiagnosis was reported as 18.5 percent. The probability that an LDCT-detected non-small cell lung cancerby far the most frequently diagnosed lung cancer typerepresents an overdiagnosis was found to be 22 percent. The overdiagnosis rate for bronchioloalveolar lung cancer was 78.9 percent.

Patz explains that the problem clinicians face is not knowing which patients are among the approximate 18 percent who have indolent disease. "Patients with these nonaggressive cancers are treated the same as any other patient with lung cancer, because it is generally not possible to distinguish indolent lesions from more aggressive tumors," says Patz. The authors emphasize the need for better biomarkers and imaging techniques to determine which lung cancers are more or less aggressive so as to optimize patient care and enhance the value of screening programs.

"Overdiagnosis is something we don't commonly think exists in lung cancer as compared with, for example, prostate cancer," says Patz. "Most often, when patients are diagnosed with lung cancer, it's viewed as a fatal disease. However, these data confirm that's not necessarily the case with screening programs, which is important information for clinicians to discuss with their patients."

"The relatively modest rate of overdiagnosis with low-dose CT compared with the overdiagnosis rate projected for other cancer screenings programs, further supports the implementation of lung cancer screening programs. Of course, it's important that we work to further drive down overdiagnosis rates across all screening programs," says Mitchell D. Schnall, M.D., Ph.D., Co-Chair of the ECOG-ACRIN Cancer Research Group and the Radiology Department Chair at the University of Pennsylvania's Perelman School of Medicine.


'/>"/>

Contact: Shawn Farley
PR@acr.org
703-648-8936
American College of Radiology
Source:Eurekalert

Page: 1 2

Related biology technology :

1. The Zacks Analyst Blog Highlights: Celgene, Biogen, Gilead, Orexigen and Cubist
2. How to Enhance Scientific Intuition in Pharmaceutical R&D: the CBCD Highlights a Revolutionary New Technology
3. Amgen to Highlight New Evolocumab (AMG 145) Data at Upcoming American Heart Association Scientific Sessions 2013
4. Bend Research to Highlight Latest Drug Formulation Technologies
5. Pittcon 2014 Announces Highlights of Annual Waters Symposium
6. The Zacks Analyst Blog Highlights: Eaton, Baxter International, Bio-Rad Laboratories, INSYS Therapeutics and Boston Scientific
7. SCAI Paper Highlights Best Practices For Diagnosing And Treating Blocked Arteries Via The Wrist
8. Apache's New Video Highlights Benefits of Employee Ownership
9. SACHEM Booth #1441 At SEMICON Europa Oct 8-10th, Highlighting Envure Systemâ„¢
10. The Zacks Analyst Blog Highlights: SPDR Health Care Select Sector Fund, SPDR S&P 500, SPDRS&P Biotech ETF, PowerShares S&P SmallCap Health Care Portfolio and PowerShares Dynamic Biotechnology & Genome Portfolio
11. Cellular Biomedicine Group Reports Second Quarter and First Half 2013 Financial Results and Business Highlights
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... , July 11, 2014 /PRNewswire-iReach/ -- Maxim Peptide, a ... that are used solely in scientific experiments, is currently ... years in business, Maxim Peptide, which was created by ... a new and updated website that now features a ... has been updated with fascinating articles about peptide research, ...
(Date:7/11/2014)... Research and Markets  has announced the ... Global Industry Analysis, Size, Share, Growth, Trends and Forecast ... http://photos.prnewswire.com/prnh/20130307/600769 Transfection is ... or RNA) into cells. This technology helps the cells ... protein metabolism by affecting the nuclear genes. The transfection ...
(Date:7/11/2014)... GENEVA , July 11, 2014 ... pleased to announce the appointment of John P. ... Campus Biotech   in  Geneva . ... on Campus Biotech in Geneva , ... internationally recognised neuroscientists. John P. Donoghue , founder ...
(Date:7/11/2014)... 2014  Researchers have pioneered a revolutionary new ... technology, called Virtual Finger, allows scientists to move ... and synapses using the flat surface of their ... imaging studies orders of magnitude more efficient, saving ... across many areas of experimental biology. The software ...
Breaking Biology Technology:Maxim Peptide Celebrates Second Anniversary Online with an Updated Website and Special Deals Section 2International Transfection Technology Market - Industry Analysis, Size, Share, Growth, Trends and Forecast to 2019 2John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 2John P. Donoghue is Taking the Lead at the Wyss Center and is Appointed Professor at EPFL and University of Geneva 3Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 2Virtual Finger Enables Scientists To Navigate And Analyze 3D Images Of Complex Biological Structures 3
... School of Economics and Political Science (LSE), Chatham ... on Emerging Nanotechnologies (PEN), an initiative of Woodrow ... Charitable Trusts, have been awarded a $587,000 European ... on regulating nanotechnologies in the European Union and ...
... Prevent HIV from Replicating, GAITHERSBURG, Md., Feb. ... gene therapies for HIV and genetic,diseases, presented results ... gene,therapy for the treatment of AIDS, at the ... in Boston, MA., "This appears to be ...
... Novavax, Inc. (Nasdaq:,NVAX) a clinical-stage vaccine company, ... Executive Officer, will be presenting at the,BIO CEO ... 12, 2008 at the,Waldorf=Astoria Hotel in New York. ... strategy, research and development progress. A link to ...
Cached Biology Technology:European Commission gives grant to investigate transatlantic oversight of nanotech 2European Commission gives grant to investigate transatlantic oversight of nanotech 3VIRxSYS Announces Interim Results from VRX496 Gene Therapy Phase II Trial 2
(Date:7/10/2014)... Colo. , June 27, 2014  The ... the National Institute of Standards and Technology (NIST) ... of its academic research and forensic science expert ... The Board is an element of the NIST,s ... members are among the first appointments made to ...
(Date:7/10/2014)... July 2, 2014  Unisys Corporation,s (NYSE: UIS ... Nederland N.V., today announced that it has been selected by ... manage a new Basic Provision Biometrics solution for penitentiaries across ... won the contract with a solution based on its open ... term of the contract is up to seven years, with ...
(Date:7/10/2014)... , July 3, 2014 Research ... addition of the "Global Gesture Recognition & ... - Forecasts to 2020" report to their ... Global Gesture Recognition & Touch-Less Sensing Market ... around for a while, but the companies were ...
Breaking Biology News(10 mins):Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 2Ten Members of the American Academy of Forensic Sciences Appointed to Forensic Science Standards Board (FSSB) 3Unisys Delivers New Basic Provision Biometrics Solution to Dutch Custodial Institutions Service 2Unisys Delivers New Basic Provision Biometrics Solution to Dutch Custodial Institutions Service 3Global Gesture Recognition & Touch-Less Sensing (2D, 3D, Ultrasonic, IR, Capacitive) Market - Forecasts to 2020 2
... 21 researchers from 11 nations, including professor Robert "JJ" Orth ... first-ever study of the risk of extinction for individual seagrass ... the International Union for the Conservation of Nature (IUCN), shows ... at an elevated risk of extinction, while 3 species qualify ...
... who reported not taking a daily prenatal vitamin immediately before ... as likely to have a child with an autism spectrum ... the associated risk rose to seven times as great when ... at the UC Davis MIND Institute has found. "Mothers ...
... body against infection don,t huff and puff, but some ... against infection don,t huff and puff, but some of ... steam engine. Weizmann Institute scientists have discovered a mechanism ... when the inflammatory mechanism that protects cells against viruses ...
Cached Biology News:New study provides global analysis of seagrass extinction risk 2Women who start prenatal vitamins early are less likely to have children with autism 2Women who start prenatal vitamins early are less likely to have children with autism 3Women who start prenatal vitamins early are less likely to have children with autism 4Immune system release valve 2
... Taura Syndrome Virus Coat Protein ... tested applications). ... MNDIPITNQN VVLSKNVTDN LFEVQDQALI ESLSRDVLLH NDSWTSSDDE ... terminal amino acids 25/100 of ...
Purified Mouse anti-Hu Actopaxin (pS8) Storage Temperature: Refrigerate(2 to 8C)...
... FastPlax Antibody is used to detect the ... surface of infected cells as early as ... of the FastPlax Titer Kit, which allows ... hours. The FastPlax Antibody can ...
b-Catenin (pSer675), phospho-specific...
Biology Products: