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NIMOTUZUMAB DEMONSTRATES EFFICACY IN RANDOMIZED HEAD & NECK CANCER STUDY WITHOUT THE TOXICITIES ASSOCIATED WITH OTHER EGFR DRUGS
Date:6/1/2009

events were noted.

    Comparison of Efficacy Parameters - Reddy BK et al study vs. Pfister DG
    et al study
    -------------------------------------------------------------------------
    PARAMETER                            Nimotuzumab + CRT   Cetuximab + CRT
    -------------------------------------------------------------------------
    Number of patients                             20                22
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    Male (%)                                       87                91
    -------------------------------------------------------------------------
    Median KPS                                     80                90
    -------------------------------------------------------------------------
    Disease site (%)
    -------------------------------------------------------------------------
      Oral cavity                                  22                14
    -------------------------------------------------------------------------
      Oropharynx                                   43                59
    -------------------------------------------------------------------------
      Hypopharynx                                  22                 5
    -------------------------------------------------------------------------
      Other                                        13                22
    -------------------------------------------------------------------------
    Stage (%)
    -------------------------------------------------------------------------
      III                                          13                14
    -------------------------------------------------------------------------
      IV                                           87                86
    -------------------------------------------------------------------------

The Reddy BK et al study was a randomized study
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SOURCE YM BioSciences Inc.
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