Navigation Links
NIH grants $750,000 to develop device to determine temperature of neonate's brain
Date:9/2/2007

NORFOLK, Va. -- A neonatologist at Childrens Hospital of The Kings Daughters (CHKD) is leading the clinical trials of a $750,000 study funded Friday, Aug. 31, to develop a device to measure the precise temperature of a newborns brain.

The National Institutes of Health (NIH) grant stems from recent studies showing that cooling of the brain of oxygen-starved newborns dramatically reduces the incidence of Cerebral Palsy, other neurological damage, and death.

While recent studies have demonstrated the effectiveness of the brain-cooling regimen, doctors dont yet have a precise way to measure the brains temperature. The NIH grant will allow researchers to adapt a non-invasive radiometric-sensing device -- developed by Meridian Medical Systems of Woolwich, ME -- to provide precise temperatures of brain tissue beneath the skull.

Precise brain temperature measurements are essential to maximize the benefit of therapeutic hypothermia, said Thomas Bass, M.D., a neonatologist at CHKD, the pediatric teaching hospital of Eastern Virginia Medical School (EVMS) in Norfolk, VA. Bass is also an EVMS professor of pediatrics.

About two to three in 1,000 newborns born at term are at risk of brain damage from oxygen-deprivation during birth. About half of the infants born with the condition will die or suffer severe handicaps such as mental retardation or cerebral palsy.

Historically, doctors tended to keep newborns warm, at incubator-like temperatures, and treated the hypoxic infants with medicine. But several recent studies have demonstrated that cooling the brain can significantly reduce both death and severe disability.

Injury from oxygen-deprivation continues long after delivery, said Bass, co-investigator of a groundbreaking study on the subject published in Pediatric Neurology in 2005. Cooling the brain decreases its need for oxygen and can slow or stop continuing damage.

Doctors today often cool the brain using whole-body cooling blankets or specially developed cooling caps. The goal of the therapy is to reduce the brain temperature by about four degrees centigrade. While cooling therapy has become more common, doctors must extrapolate the brains temperature by using a rectal thermometer. The rectal temperature can be off by as much as two degrees.

Thats not acceptable, said Bass.

Under the NIH grant, Bass, Meridian and a team of EVMS research scientists will exploit the fact that all human tissue emits energy at microwave frequencies. Those emissions can travel through tissue, but only for a few millimeters, depending on the frequency. As the tissues temperature rises, emissions increase.

By tabulating the frequency and strength of electromagnetic emissions emanating from the body, Meridian has developed a device that can measure the temperature of tissue a given distance below the skins surface, even through a babys skull.

The research team hopes to use this technology to develop a small, lightweight device that can be affixed to an infants head to detect electromagnetic emissions generated 15 millimeters below the surface, giving doctors the exact temperature of the childs brain.


'/>"/>
Contact: Greg Raver-Lampman
Greg.Lampman@CHKD.org
757-668-7554
Children's Hospital of The King's Daughters
Source:Eurekalert

Related biology technology :

1. State to offer $850K in high-tech training grants
2. Grants worth $800,000 help BellBrook Labs develop products
3. Venture-backed firms could become eligible for federal SBIR grants
4. Mithridion wins grants for Alzheimers research
5. NASDAQ grants Merge more time for compliance
6. Morgridge seed grants attract over 220 proposals
7. Medical College researchers win federal grants
8. NSF grants bolster integrative graduate study at UW-Madison
9. Three state businesses receive technology grants
10. SBC Foundation awards technology grants in Wisconsin
11. Visonex plans to expand with state grants, loan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/7/2016)... , Dec. 7, 2016  Genprex, Inc. a ... immunogene therapy treatments, today announced that it has ... a leading strategic communications and advisory firm, to ... The program will combine investor relations, public relations ... raising the profile of Genprex and its lead ...
(Date:12/7/2016)... ... December 07, 2016 , ... ... today a new service to enable rapid migration of large pathology data sets ... one of the factors limiting adoption of digital pathology. Proscia’s free massive dataset ...
(Date:12/6/2016)... Dec. 6, 2016 /PRNewswire/ - SQI Diagnostics Inc. ("SQI" or the "Company") ... the fourth quarter and fiscal year ended September 30, 2016. ... , , ... life sciences and diagnostics company that develops and commercializes proprietary technologies ... Achieved revenues of $1.4 million more than tripling ...
(Date:12/6/2016)... ... December 06, 2016 , ... Symbios Technologies, Inc. , ... company has engaged in a collaborative research partnership with Colorado State University (CSU) ... of the Vice President for Research. This agreement is designed to further the ...
Breaking Biology Technology:
(Date:11/24/2016)... 23, 2016 Cercacor today introduced Ember TM ... trainers non-invasively measure hemoglobin, Oxygen Content, Oxygen ... Respiration Rate in approximately 30 seconds. Smaller than a ... immediate access to key data about their bodies to ... regimen. Hemoglobin carries oxygen to muscles. ...
(Date:11/22/2016)... Minn. , Nov. 22, 2016   MedNet ... supports the entire spectrum of clinical research, is pleased ... Medical LiveWire Healthcare and Life Sciences Awards ... award caps off an unprecedented year of recognition and ... trials for over 15 years. iMedNet ...
(Date:11/19/2016)... 18, 2016 Securus Technologies, a leading provider ... safety, investigation, corrections and monitoring, announced today that it ... to have an independent technology judge determine who has ... high tech/sophisticated telephone calling platform, and the best customer ... do most of what we do – which clearly ...
Breaking Biology News(10 mins):