Navigation Links
NIH funds support UAB joint replacement research
Date:7/20/2009

BIRMINGHAM, Ala. Newly announced National Institutes of Health (NIH) funding will expand the reach of ongoing University of Alabama at Birmingham (UAB) research into a unique nanostructured coating to improve the performance and longevity of total joint replacement components. The broadened UAB research opportunity is funded by a four-year, $790,931 National Institutes of Health (NIH) grant through the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

UAB's research, titled Bioengineering Research Partnership (BRP) in Total Joint Replacements, will explore next-generation technology to improve the service life of total joint replacements, which UAB researchers believe could dramatically cut the number of recurrent surgical procedures performed each year, said Yogesh Vohra, Ph.D., the BRP's principal investigator and director of the Center for Nanoscale Materials and Biointegration (CNMB) in the UAB School of Natural Sciences and Mathematics.

Vohra said the BRP opportunity will unite his UAB interdisciplinary research team with professionals at Smith and Nephew Inc., an international leader in the development of advanced medical devices. The company is known globally for its OXINIUMTM oxidized zirconium material for joint replacements.

"We have been researching our nanostructured multilayer diamond coating for a number of years inside our UAB facilities but there have been limitations to just how rigorous the testing could be," Vohra said. "The funding to partner with Smith and Nephew expands our research options because it offers us access to the company's resources and talent."

Among the benefits, Vohra said, the BRP allows access to Smith and Nephew's hip and knee simulators, which offer UAB researchers the most realistic testing conditions to date for their coating technology. Working with the multi-million dollar simulators should strongly indicate how well the team's nanostructured multilayer diamond coatings reduce the friction and wear on the metal components of orthopaedic devices, Vohra said. The team also will be able to examine the cellular and tissue responses to the technology and confirm that there is no toxicity effect from any wear debris that is generated.

"This partnership is central to advancing our research toward more reliable and efficient joint replacements," Vohra said. "We are gaining access to state-of-the-art testing equipment while benefitting from Smith and Nephew's experience as the industry leader in advanced bearing-surfaces for joint replacement implants."

The BRP also helps put the UAB coating technology on the fast track for commercialization, as it will foster the private industry relationship necessary to secure investment and production capacity, Vohra said.

The overall clinical impact of the BRP research is to drive down the number of recurrent surgical procedures for joint replacement recipients, who are living longer and pushing the longevity limits of their devices, Vohra said. The American Academy of Orthopaedic Surgeons reports that 15 to 20 percent of annual total joint replacement procedures are recurrent, or revision, surgeries. Vohra said the nanostructured diamond-coated devices should reduce the metal ion release to the surrounding tissues and perform better during long-term implantation in the human body, which could significantly cut the follow-up surgery rate.


'/>"/>

Contact: Andrew Hayenga
ahayenga@uab.edu
205-427-7423
University of Alabama at Birmingham
Source:Eurekalert  

Related biology technology :

1. NeoStem Raises Additional Funds from Principals of Suzhou Erye Pharmaceuticals Company Ltd. and U.S. Institutional and Private Investors, Bringing the Total Recent Financings to Over $15 Million; Funds Will Support Expansion Activities in the United State
2. Printing New Organs: Foundation Funds Medical Technology That Replicates Human Tissue
3. Obama Budget Level Funds Career Technical Education
4. Immune Targeting Systems Completes Second Tranche of Series-A Funding Bringing Total Funds Raised to More Than GBP5m
5. LI-COR Biosciences Offers $1.75 Million in Matching Funds for Undergraduate Genomics Education
6. Hoana Medical and Hawaii Union Health and Welfare Trust Funds Partner to Fix Healthcare
7. NIH Funds $1M Research at Quest Product Development and University of Colorado for New Digitally-Controlled Endoscopes
8. Notice of Initial Distribution of Net Settlement Funds
9. NSF Funds New Entrepreneurship Program
10. NIH Funds Vaccine Research for Needle-free and Self-Administered Protection Against Pandemic Influenza
11. University of Florida Shands Cancer Center Selects OnCore(r) to Support its Collaborative Research Goals
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
NIH funds support UAB joint replacement research
(Date:6/27/2016)... , ... June 27, 2016 , ... Parallel 6 ... trials, announced today the Clinical Reach Virtual Patient Encounter CONSULT module which ... with the physician and clinical trial team. , Using the CONSULT module, patients and ...
(Date:6/27/2016)... --  Ginkgo Bioworks , a leading organism design ... awarded as one of the World Economic Forum,s ... innovative companies. Ginkgo Bioworks is engineering biology to ... in the nutrition, health and consumer goods sectors. ... including Fortune 500 companies to design microbes for ...
(Date:6/24/2016)... NC (PRWEB) , ... June 24, 2016 , ... Researchers ... the most commonly-identified miRNAs in people with peritoneal or pleural mesothelioma. Their findings are ... to read it now. , Diagnostic biomarkers are signposts in the blood, lung ...
(Date:6/23/2016)... 23, 2016 /PRNewswire/ - FACIT has announced the ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" or ... of a portfolio of first-in-class WDR5 inhibitors for ... as WDR5 represent an exciting class of therapies, ... medicine for cancer patients. Substantial advances have been ...
Breaking Biology Technology:
(Date:6/16/2016)... , June 16, 2016 ... size is expected to reach USD 1.83 billion ... Grand View Research, Inc. Technological proliferation and increasing ... applications are expected to drive the market growth. ... , The development of advanced multimodal ...
(Date:6/3/2016)... 2016 Das DOTM ... Nepal hat ein 44 Millionen ... Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, an ... und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte internationale ... teilgenommen, aber Decatur wurde als konformste und ...
(Date:5/24/2016)... 24, 2016 Ampronix facilitates superior patient care by providing unparalleled technology to ... display is the latest premium product recently added to the range of products distributed ... ... ... Imaging- LCD Medical Display- Ampronix News ...
Breaking Biology News(10 mins):