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NIH SPECIAL Science SERIES: Groundbreaking Molecules to Revolutionize Autophagy Induction for Treating Huntington’s Disease, and potentially Alzheimer’s and Parkinson's
Date:2/1/2017

One Million Solutions in Health has a one-of-a-kind partnership with the NIH to share new technologies and findings through the NIH Special Science Series. These technologies have been available for licensing and/or collaboration projects. This webinar highlights "Groundbreaking Molecules that will Revolutionize Autophagy Induction for Treating Huntington’s Disease, and potentially Alzheimer’s and Parkinson’s Diseases" and is presented by Dr. Lori Griner, Post-doctoral Research Fellow, NICHD, NIH and Dr. Melvin L. DePamphilis, Section Chief, NICHD, NIH.

This groundbreaking discovery features five small molecules that lower mutant huntingtin protein (HTT) in primary cells from Huntington’s, Alzheimer’s and Parkinson’s patients, and a cell culture model for Huntington’s disease. These target a major strategy in the treatment of these diseases in a new and unique way.

These small molecules were discovered based on their ability to induce autophagy, a cellular process whereby components of the cytoplasm are degraded. Current progress in the autophagy and Huntington’s disease fields show that autophagy induction in in vitro and in vivo models, lowers mutant HTT protein and improves disease symptoms, making autophagy induction a promising strategy for treating Huntington’s disease, and potentially Alzheimer’s and Parkinson’s disease patients.

Currently, there is a need for safe and effective inducers of autophagy for patients. More importantly, there is no cure for Huntington’s, Alzheimer’s or Parkinson’s — with the current treatment only targeting the minimization of symptoms. Due to the large unmet need of effective treatment options for these types of patients, and the promise of autophagy induction as a therapeutic strategy, this technology holds an enormous value.

Review the webinar here: "Groundbreaking Molecules that will Revolutionize Autophagy Induction for Treating Huntington’s Disease, and potentially Alzheimer’s and Parkinson’s Diseases".

ABOUT ONE MILLION SOLUTIONS IN HEALTH:

As a not-for-profit, the goal of One Million Solutions in Health™ is to shape health care by sharing solutions and, importantly, to accelerate the discovery, development and delivery ... of innovative cures, treatments and preventative measures for patients around the world. By facilitating efforts to ensure organizations can Connect, Learn + Share, Innovate and Collaborate, our vision is to improve health care delivery, accelerate life sciences research and share patient and consumer-focused ideas and solutions.

By engaging scientists, entrepreneurs, investors, innovators, industry experts, health care professionals, and patients across various disciplines, and from around the world, we can utilize the power of the internet to disrupt things in a positive and transformative way to accelerate the movement of new solutions and scientific discoveries from the scientist to the patient.

The Technology Evaluation Consortium (TEC) brings together life sciences and/or health care companies and technology providers, and other relevant partners (e.g., government and Universities) to evaluate and validate technologies or services in a collaborative environment. The model empowers technology providers and industry end users to collectively assess a number of technologies in a cost-effective manner, producing a depth and breadth of results that no company can achieve alone.

We are on our way towards accelerating high-potential innovations, catalyzing investment and increasing awareness of, and support for, important ideas to improve health and save lives. We are thrilled to have you be a part of this transformative journey!

IF YOU HAVE A TECHNOLOGY, SCIENTIFIC DISCOVERY OR MEDICAL SOLUTION YOU WOULD LIKE US TO HELP SHARE WITH THE WORLD, CONTACT US.

For more information: http://www.onemillionsolutionsinhealth.org

CONTACT:

One Million Solutions in Health™
Dawn Van Dam
Executive Director & CEO
Email: dawn.vandam(at)onemillionsolutionsinhealth(dot)org
Phone: 416-402-8274
Twitter: @DawnVanDam

Read the full story at http://www.prweb.com/releases/2017/02/prweb14033194.htm.


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