NEWSWEEK: Media Lead Sheet/December 10, 2007 Issue (on newsstands Monday, De...( http://www.ne Jogging Your Memory...)

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"Jogging Your Memory" (p. 68). Reporter Anne Underwood reports on memory loss and the ways people can keep their minds sharper than ever. There are many hypotheses about why our powers of recall go awry over time, but it's clear that both committing new information to memory and retrieving it become more difficult. Now scientists are busy looking into the workings of how the mind creates and stores memories to better understand age-related declines in retention as well as developing drugs and exercises that help push your aging brain to recall more.

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"Bones of Invention" (p. 88). Contributing Editor Barbara Kantrowitz reports on the new research and insights into the complex hormonal symphony sustaining the human skeleton, and why fractures are caused by the most common bone disease, osteoporosis. In the last 15 years, scientists have focused on drugs that slow bone loss; the most well known of these are part of a group called bisphosphonates. But a new generation of drugs aims to build bone. These could work in concert with bisphosphonates or other medications that slow bone loss to re-create the balance necessary for the growth of healthy bone. Other researchers are looking at ways of using stem-cell technology to produce new bone.

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IRAN: "The Gates Keeper" (p. 32). Deputy Washington Bureau Chief Dan Ephron, Senior Editor Michael Hirsh and Editor-at-Large Evan Thomas report that Defense Secretary Robert Gates is seen as the best insurance that the Bush administration will not leave a legacy of ashes in Iran. Gates gives the Washington foreign-policy establishment hope that the pendulum is swinging back, that it is possible to forge a foreign policy by
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