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Multiple Vimpat(R) (lacosamide) Studies Presented at American Epilepsy Society Annual Meeting
Date:12/8/2008

atients with seizure disorders, Vimpat(R) should be gradually withdrawn to minimize the potential of increased seizure frequency. Multiorgan hypersensitivity reactions have been reported with antiepileptic drugs. If this reaction is suspected, treatment with Vimpat(R) should be discontinued.

AEDs increase the risk of suicidal behavior and ideation. Patients taking Vimpat(R) should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior, and/or any unusual changes in mood or behavior.

The most common adverse reactions occurring in >10 percent of Vimpat(R)-treated patients, and greater than placebo, were diplopia, headache, dizziness, and nausea.

The FDA has recommended Vimpat(R) as a schedule C-V controlled substance. Scheduling is expected to be finalized in the first quarter of 2009.

Please go to http://www.fda.gov/cder/foi/label/2008/022253lbl.pdf for approved prescribing information.

    Further information
    Andrea Levin
    Public Relations Manager
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    Eimear O'Brien,
    Global CNS Communications Manager, UCB Group
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    Eimear.OBrien@ucb-group.com

About UCB

UCB is a global leader in the biopharmaceutical industry dedicated to the research, development and commercialization of innovative medicines with a focus on the fields of central nervous system and immunology disorders. Employing approximately 12,000 people in more than 40 countries, UCB achieved revenue of 3.6 billion euro in 2007. UCB is listed on NYSE Euronext (symbol: UCB). Worldwide headquarters is located in Brussels, Belgium; U.S. headquarters is located in Atlanta, Georgia. F
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