Navigation Links
Multiple Types of Heart Attacks Reduced by Prasugrel in TRITON-TIMI 38 Trial

orrow, M.D. M.P.H., Associate Professor of Medicine at Harvard Medical School and a Senior Investigator with the TIMI Study Group, Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA.

Investigators classified 1,218 heart attacks that occurred during the TRITON-TIMI 38 study based on the Universal Definition of Myocardial Infarction. This definition includes a new classification system to characterize different types of heart attacks based on the size and type of heart attack.(3) The types of heart attacks evaluated in this study, according to the definition, included:

  • Type 1: Spontaneous heart attack caused by a primary coronary event, such as a plaque rupture in a coronary artery with less blood then flowing to the muscle
  • Type 2: Secondary heart attack due to either increased oxygen demand or decreased supply due to other conditions such as spasm of the coronary artery or low blood oxygen from anemia
  • Type 3: Sudden cardiac death with evidence of a heart attack
  • Type 4: Heart attacks related to a PCI
    • Type 4a: Heart attacks associated with a PCI procedure
    • Type 4b: Heart attacks associated with stent thrombosis as documented by an angiography or at autopsy
  • Type 5: Heart attack associated with coronary artery bypass graft (CABG).

The investigators examined the size and timing of a new heart attack, as well as whether or not the heart attack was associated with an elevation of the ST segment on the electrocardiogram (noted as STEMI and NSTEMI).

The results of the analysis showed:

  • The rate of spontaneous heart attacks (Type 1) was 2.5 percent in patients taking prasugrel compared with 3.4 percent in those taking clopidogrel (p=0.0

SOURCE Eli Lilly and Company
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. Agendia to Present Multiple Predictive and Prognostic Studies on Breast and Colorectal Cancers at ASCO Annual Meeting
2. BioMS Medicals pivotal international multiple sclerosis trial receives positive review from Data Safety Monitoring Board
3. Ascenta Therapeutics Announces Results of Preclinical Evaluation of AT-406 in Multiple Cancer Models
4. BioMS Medicals phase III U.S. multiple sclerosis trial receives positive safety review from Data Safety Monitoring Board
5. Biovista Inc. Announces Positive Efficacy Results in a Pre-Clinical Trial of its BVA-101 Repositioned Drug for Multiple Sclerosis
6. Intrinsic Bioprobes, Inc. Enters into a $1.27M Contract with the National Cancer Institute to Develop Multiplex Mass Spectrometric Immunoassays for Detection of Low Abundance Cancer-Related Proteins
7. First Multiple Dose Clinical Trial of TorreyPines Therapeutics Oral Compound NGX426 Demonstrates Compound Is Safe and Well-Tolerated
8. BioMS Medical reports results of exploratory phase II trial of dirucotide in relapsing remitting multiple sclerosis
9. International Guidelines for First-Line use of Freelite(TM) in Diagnosis and Management of Multiple Myeloma to be Published in "Leukemia"
10. Proteolix Announces Positive Data From Two Ongoing Phase 2 Clinical Trials of Carfilzomib in Multiple Myeloma at the 50th Annual Meeting of the American Society of Hematology
11. EntreMed Initiates ENMD-2076 Clinical Trial in Multiple Myeloma
Post Your Comments:
(Date:10/8/2015)... 2015 .   ... Goldman Small Cap Research, a stock market ... microcap sectors, announced today that it has published ... Inc. (OTCQB - PMCB), a publicly traded, clinical ... treatments for cancer and diabetes. To view the ...
(Date:10/8/2015)... , Oct. 8, 2015 /PRNewswire/ - RepliCel Life Sciences Inc. ... company focused on the development of autologous cell therapies, today ... partnering meetings taking place in the month of October: ... Partnering Forum RepliCel will be presenting at the ... on the Mesa to be held October 7-9 in ...
(Date:10/8/2015)... CA (PRWEB) , ... October 08, 2015 , ... ... mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene and results in ... viscous and sticky mucus accumulates in the lungs. This mucus is very difficult ...
(Date:10/7/2015)... , Oct. 7, 2015  ChromaDex Corp. ... and nutritional ingredients that creates science-based solutions for ... nutrition, and pharmaceutical products, today announced that the ... CEO and Founder, is now available for on-demand ... -->   --> ...
Breaking Biology Technology:
... , ... integral to the SPEX FLUOROMAX -P or as an accessory ... information on various systems of chemical and biochemical interest, by revealing data ... <P,>This Application Note describes an example, using the SPEX ...
... , ... DataMax is the software used to display data from all SPEX ... a contour map. A contour map displays multifiles or 3-D data, and ... meteorological plot of barometric pressures. X values are plotted on the horizontal ...
... Introduction , ... 1 O 2 , is of considerable interest in environmental applications, ... been directed towards understanding the biological effects of 1 O 2 ... a dye, oxygen, and light. <P,>An understanding of the mechanisms that produce ...
Cached Biology Technology:
(Date:9/30/2015)... -- The global glucose monitoring device and diabetes management market is ... report on the industry from Kalorama Information. Sales in the traditional ... by continuous glucose monitoring and sensor segment, according to the ... products in its latest report, The Global Glucose Monitoring ... , ...
(Date:9/28/2015)... YORK , Sept. 28, 2015 /PRNewswire/ ... announced today that its expedited traveler service ... innovative platform transforms travel, bringing a frictionless ... its members. "CLEAR offers our ... enhances customer service," said Jim Smith ...
(Date:9/28/2015)... -- According to a new market research ... & Others), Application (Access Control & Others), Industry (Travel ... Global - Forecast to 2020", published by MarketsandMarkets, the Iris ... by 2020, at a CAGR of 23.40% between 2015 ... T ables and 66 Figures spread ...
Breaking Biology News(10 mins):
... that the dawn of agriculture may have come with ... some 11,400 years ago, roughly a thousand years before ... in the region. The discovery dates domesticated figs to ... making the fruit trees the oldest known domesticated crop. ...
... combining the four bacterial surface proteins that generate ... the University of Chicago have created a vaccine ... drug-resistant strains of Staphylococcus aureus, the most common ... source of community-associated illness. , The vaccine ...
... June 15th issue of G&D, Dr. Marie-Louise Hammarskjold (UVA) ... the Wilms' Tumor 1 tumor suppressor. The Wilms' Tumor ... pathological human development, with known roles in kidney and ... , Dr. Hammarskjold and colleagues reveal that WT1 works ...
Cached Biology News:
... a silica based spin filter membrane to isolate ... DNA band is cut from an agarose gel ... The gel slice is melted irreversibly in a ... bound to the silica spin filter membrane and ...
... incorporation of Br-dUTP results in a stronger ... a fluorescein-labeled anti-BrdU antibody. Propidium iodide/RNase ... to counterstain the total DNA. Features and ... improved detection than found by using biotin- ...
Mouse polyclonal antibody raised against a partial recombinant WRB. NCBI Entrez Gene ID = 7485...
Biology Products: