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Multigene Test Predicts Who Could Avoid Chemotherapy Despite Positive Lymph Nodes in Early Breast Cancer
Date:12/13/2007

a group of women with positive nodes who do not appear to benefit from anthracycline-based chemotherapy.

Dr Albain concluded, "These data collectively challenge chemotherapy mandates for patients with node-positive, ER-positive disease: not all benefit from chemotherapy, whereas others derive greater benefit than previously predicted. SWOG 8814 joins a suite of studies that provide a consistent message regarding the value of the RS for individualized adjuvant therapy, and for the first time shows its value in a population of women with node-positive breast cancer who were treated with a tamoxifen-alone control. These findings should be discussed with women diagnosed with early breast cancer who fit the criteria for this study."


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SOURCE San Antonio Breast Cancer Symposium
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