Navigation Links
MultiCell Technologies Files U.S. Patent Application for Targeted Delivery of MCT-485, a Noncoding miRNA for Cancer Treatment
Date:11/13/2013

WOONSOCKET, R.I., Nov. 13, 2013 /PRNewswire/ -- MultiCell Technologies, Inc. (OTC Bulletin Board: MCET.OB) has filed a second U.S. patent application concerning methods and formulations to achieve targeted tumor cell death.  MCT-485 is a noncoding double stranded micro RNA (miRNA) which has demonstrated oncolytic and immune stimulating activity in in vitro models of hepatocellular carcinoma.  MCT-485 is currently being evaluated in animal models of hepatocellular carcinoma.

This invention addresses the need to direct the powerful biological effect of miRNAs such as MCT-485 towards tumor cells and away from normal tissues.  This patent application describes compositions and methods that target populations of cancerous cells which have an enhanced capability to mediate the process of relapse, progression and metastasis.  Not all cancer cells have a tumor initiating capability; this U.S. patent application describes compositions and methods that target cancer by delivering a biologically active, cytotoxic payload of miRNA to only those cells having the highest tumor initiating capability that are part of the cancerous process such as cancer stem cells and tumor initiating cells, and to kill those cells without killing cells not directly involved in the process of relapse, progression and metastasis of cancer.

Hepatocellular carcinoma is the most common form of primary liver cancer, and is a leading cause of cancer death worldwide.  Over 1 million cases of hepatocellular carcinoma are reported annually.  Current approaches for treatment of hepatocellular carcinoma are of limited efficacy.  MCT-485, possessing both oncolytic and immune activating properties, could be superior to doxorubicin, cisplatin and other currently marketed therapies by providing a more robust activation of immunity, and a more global and longer lasting anti-tumor effect.

About MCT-485

MultiCell Techn
'/>"/>

SOURCE MultiCell Technologies, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. MultiCell Technologies Expands Scope of Research Agreement for the Treatment of Liver Cancer
2. MultiCell Technologies Announces Positive Preclinical Results for MCT-465 and MCT-485 in Primary Liver Cancer In Vitro Models
3. Life Technologies Announces Third Quarter 2013 Results
4. Bend Research to Highlight Latest Drug Formulation Technologies
5. BioSpecifics Technologies Corp. to Host Conference Call to Report Third Quarter 2013 Financial Results on Tuesday, November 12, 2013
6. BioStorage Technologies Selected to Provide Technical Consulting to Chinese National Genebank
7. Adaptive Biotechnologies Publishes Gold Standard Method for Sequencing Cells of the Adaptive Immune System
8. BCC Research Publishes a New Report On Global Markets for Rnai Technologies
9. Forensic Technologies and Services - 2013 Global Strategic Business Report
10. Modality Solutions Releases New White Paper on Thermal Shipping Technologies
11. NPI Volunteers Carry ‘Essential Technologies’ Message to Congress
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2015)... 2015  HealthSouth Corporation (NYSE: HLS ... post-acute healthcare services, offering both facility-based and home-based ... for the second quarter ended June 30, 2015. ... strong volume growth in both segments and an ... Grinney, President and Chief Executive Officer of HealthSouth. ...
(Date:7/29/2015)... TX (PRWEB) , ... July 29, 2015 , ... ... designer, manufacturer and supplier, announces the launch of their 2nd generation cell therapy ... the current miniPOD CT, but it also represents a new POD® design. ...
(Date:7/29/2015)... , ... July 29, 2015 , ... ... today announced its GHS Label Guide . To align chemical container labeling ... this guide includes explanations of label components, an example of an accurate label, ...
(Date:7/29/2015)... 29, 2015  Therapath Neuropathology ( www.Therapath.com ), ... with VA and Military Medical centers both domestically ... (ENFD) and Sweat Gland Nerve Fiber Density (SGNFD) ... https://therapath.com/skin ). Demonstration of a ... on punch skin biopsy is a highly sensitive ...
Breaking Biology Technology:HealthSouth Reports Results for Second Quarter 2015 2HealthSouth Reports Results for Second Quarter 2015 3HealthSouth Reports Results for Second Quarter 2015 4HealthSouth Reports Results for Second Quarter 2015 5HealthSouth Reports Results for Second Quarter 2015 6HealthSouth Reports Results for Second Quarter 2015 7HealthSouth Reports Results for Second Quarter 2015 8HealthSouth Reports Results for Second Quarter 2015 9HealthSouth Reports Results for Second Quarter 2015 10HealthSouth Reports Results for Second Quarter 2015 11HealthSouth Reports Results for Second Quarter 2015 12HealthSouth Reports Results for Second Quarter 2015 13HealthSouth Reports Results for Second Quarter 2015 14HealthSouth Reports Results for Second Quarter 2015 15HealthSouth Reports Results for Second Quarter 2015 16HealthSouth Reports Results for Second Quarter 2015 17HealthSouth Reports Results for Second Quarter 2015 18HealthSouth Reports Results for Second Quarter 2015 19HealthSouth Reports Results for Second Quarter 2015 20HealthSouth Reports Results for Second Quarter 2015 21HealthSouth Reports Results for Second Quarter 2015 22HealthSouth Reports Results for Second Quarter 2015 23HealthSouth Reports Results for Second Quarter 2015 24HealthSouth Reports Results for Second Quarter 2015 25HealthSouth Reports Results for Second Quarter 2015 26HealthSouth Reports Results for Second Quarter 2015 27HealthSouth Reports Results for Second Quarter 2015 28HealthSouth Reports Results for Second Quarter 2015 29HealthSouth Reports Results for Second Quarter 2015 30HealthSouth Reports Results for Second Quarter 2015 31HealthSouth Reports Results for Second Quarter 2015 32HealthSouth Reports Results for Second Quarter 2015 33HealthSouth Reports Results for Second Quarter 2015 34HealthSouth Reports Results for Second Quarter 2015 35HealthSouth Reports Results for Second Quarter 2015 36
... Standard Imaging , a Middleton-based provider of ... cancer cardiology and other applications, has announced the purchase ... acquired from the British Columbia-based company are the PIPSpro ... electronic portal imaging devices (EPIDs). The PIPSpro software displays, ...
... Corporation announced Tuesday it is leading the RFID pilot ... pilot will enable Unilever to implement and test RFID technology ... mandates from Wal-Mart other top retailers and the U.S. Department ... and case level next year. , ,Three Unilever locations have ...
... Thursday the availability of a new shift-bidding module designed ... open shifts based on schedule, credentials and pay schedule. ... another way for hospitals to address what the Association ... industry challenges: employee recruiting and retention. , ,After a ...
Cached Biology Technology:Standard Imaging acquires Canadian PIPSpro radiation treatment technologies 2RedPrairie leads RFID project for Unilever 2
(Date:7/31/2015)... , 31. Juli 2015 Die 10. internationale Konferenz ... BGI veranstaltet und findet vom 22. bis 25. ... , statt. Die Konferenz feiert ... Start 2006 ist die ICG weltweit zu einem ... Sie ist eines der dynamischsten, enthusiastischsten und angenehmsten ...
(Date:7/27/2015)... , July 27, 2015  Synaptics Inc. (NASDAQ: ... interface solutions, today announced that Huawei has selected ... solution for its stylish smartwatch. Huawei chose the ... reliability, low power and highly responsive human interface ... Huawei designers also required a classic round watch ...
(Date:7/21/2015)... 21, 2015 Today, ZTE announced its Android ... well as expected revenues in 2015 that relate to sales of ... guidance of approximately 2,200 MSEK for 2015. Jörgen Lantto, ... smartphone manufacturer in China and we are ... 5 for Axon , its ...
Breaking Biology News(10 mins):Die 10. internationale Konferenz zu Genomik (ICG-10) beginnt im Oktober 2Die 10. internationale Konferenz zu Genomik (ICG-10) beginnt im Oktober 3Synaptics Touchscreen Solution Powers New Huawei Watch 2Synaptics Touchscreen Solution Powers New Huawei Watch 3FPC's Touch Fingerprint Sensor FPC1025 in ZTE's Smartphone Axon 2
... Cancer Center (MSKCC) have identified a set of genes ... to remodel the network of blood vessels at the ... found to promote the spread of breast cancer to ... in this week's Nature, helps to explain how cancer ...
... shown that lithium, long the standard treatment for bipolar ... brains of patients with the illness. , The ... journal Biological Psychiatry and is currently available online. ... of psychiatry at UCLA, and Paul Thompson, associate professor ...
... brain cells can grow new extensions when the amount of ... shows. , The research examined three related receptor proteins, ... brains of rats. , When researchers increased the ... were up to three times longer than those on nerve ...
Cached Biology News:Lithium builds gray matter in bipolar brains, UCLA study shows 23 proteins may play important role in nerve-cell repair 2
...
Contains L-glutamine...
Immunogen: MBP-fusion protein of the C-terminal region of the a2 subunit (amino acids K581-D670) Storage: -20 C, Avoid Freeze/Thaw Cycles...
... Specificity: This antibody recognizes murine ... cross-react with other related IRF ... with murine IRF7 protein was ... of the 293T cells transfected ...
Biology Products: