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Mount Sinai leads program of excellence in nanotechnology with $16.5 million grant
Date:9/29/2010

Mount Sinai School of Medicine received a contract for almost $16.5 million from The National Institutes of Health (NIH) and the National Heart and Lung Institute (NHLBI) through the Program of Excellence in Nanotechnology (PEN). The contract is one of four issued nationally to develop multidisciplinary research Centers with the goal of developing nanotechnology tools for diagnosing and treating heart, lung and blood diseases. As co-principal investigator, Zahi A. Fayad, PhD, Professor of Radiology and Medicine and the Director of the Translational and Molecular Imaging Institute at Mount Sinai School of Medicine leads a team of world-renowned experts in the fields of cardiology, imaging, and bioengineering. He is joined by the center's other co-principal investigator Robert S. Langer, ScD, Massachusetts Institute of Technology, for this highly collaborative program aimed at utilizing nanotechnology to better prevent and treat cardiovascular disease.

As a leading authority in cardiovascular medicine and imaging, Mount Sinai plans to organize a Center that will develop state-of-the-art translational nanoparticle technologies to help treat and prevent atherosclerosis, heart attack, and heart failure. During the term of the five-year contract, the investigators at Mount Sinai and the other participating institutions are pursuing a three-pronged approach to the problem of cardiac disease. Investigators will explore minimally invasive nanotechnology-based advances to regenerate tissue damaged after heart attack. They will develop nanotherapies to repair defective inflammation resulting from atherosclerosis with a focus on "theranostics," or the use of nanotechnology to allow diagnostic therapy in atherosclerosis.

"There is enormous potential in the use of nanotechnology to treat cardiovascular disease, but it has remained largely unexplored," said Dr. Fayad. "Through this research, we hope to show that nanotherapies may have unprecedented benefits
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Contact: Mount Sinai Press Office
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

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