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Monogram Announces 2008 Third Quarter Financial Results
Date:10/27/2008

are is shown below in accordance with GAAP and also on a Non-GAAP Proforma Basis. The Company is reporting Non-GAAP Proforma results which exclude certain items to provide a clearer view of ongoing results without the impact of non-cash valuation adjustments related to our convertible debt. A reconciliation of these Non-GAAP Proforma results to GAAP results is included with the Statement of Operations data attached to this release.

Three Months Ended Nine Months Ended

September 30, September 30,

2008 2007 2008 2007

Net Loss ($ Millions)

GAAP Net Loss $(4.9) $(3.1) $(12.2) $(18.5)

Non-GAAP Proforma Net Loss $(6.4) (7.5) $(18.5) (25.6)

Net Loss Per Share ($)

GAAP Net Loss Per Share $(0.04) $(0.02) $(0.09) $(0.14)

Non-GAAP Proforma Net Loss Per Share $(0.05) $(0.06) $(0.14) $(0.19)

Non-cash "mark-to-market" adjustments to the 3% Senior Secured Convertible Note and the 0% Convertible Senior Unsecured Debt that were reflected in non- operating income and expense for the periods ended September 30, 2008 and 2007 are excluded from proforma net loss. Favorable adjustments of $1.5 million and $4.2 million were recorded in the three months ending September 30, 2008 and 2007, respectively. Favorable adjustments of $6.3 million and $4.7 million were recorded in the nine months ending September 30, 2008 and 2007, respectively. In addition, a favorable adjustment of $2.2 million was recorded at January 1, 2007 for the cumulative effect of the change in accounting principle at that date. Such adjustments could be significant and unpredictable in future quarters depending on several factors, including the level of the Company's common stock price.

Stock-based compensation in accordance with SFAS123(R)
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SOURCE Monogram Biosciences, Inc.
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