Navigation Links
Molecular hula hoop
Date:7/18/2008

This press release is available in German.

Humans have long been trying to make the dream of nanoscopic robots come true. The dream is, in fact, taking on some aspects of reality. Nanoscience has produced components for molecular-scale machines. One such device is a rotor, a movable component that rotates around an axis. Trying to observe such rotational motion on the molecular scale is an extremely difficult undertaking. Japanese researchers at the Universities of Osaka and Kyoto have now met this challenge. As Akira Harada and his team report in the journal Angewandte Chemie, they were able to get "snapshots" of individual molecular rotors caught in motion.

As the subject of their study the researchers chose a rotaxane. This is a two-part molecular system: A rod-shaped molecule is threaded by a second, ring-shaped molecule like a cuff while a stopper at the end of the rod prevents the ring from coming off. The researchers attached one end of the rod to a glass support. To observe the rotational motions of the cuff around the sleeve, the scientists attached a fluorescing side chain to the cuff as a probe.

To observe the rotation of the ring around the rod, the researchers used a microscopic technique called defocused wide-field total internal reflection fluorescence microscopy. This gave snapshots of individual rotaxane molecules in the form of emission patterns. In simplified terms, if the cuff is motionless, the patterns make it possible to calculate the direction in which the probe emits its fluorescent light. This makes it possible to calculate the orientation of the cuff, which remains constant for every snapshot. However, if the cuff is rotating, the emission pattern does not reveal the spatial orientation of the probe.

The researchers showed that the cuff of the rotaxane does not rotate if the sample is dry. However, when it is wet they
'/>"/>

Contact: Akira Harada
harada@chem.sci.osaka-u.ac.jp
81-668-505-445
Wiley-Blackwell
Source:Eurekalert  

Page: 1 2

Related biology technology :

1. Center for Molecular Medicine Only Regional Provider of Test Suggested in FDA Alert on Prescribing Codeine to Nursing Mothers
2. Amsterdam Molecular Therapeutics to Release H1 2007 Results on August 29, 2007
3. Amsterdam Molecular Therapeutics Reports Half Year Results 2007
4. Rosetta Genomics to Present at the American Association of Cancer Research (AACR) "Molecular Diagnostics in Cancer Therapeutic Development" Conference
5. Glycominds Joins Biomolecular Photonic (BMP) Consortium to Develop New Molecular Imaging Technique
6. Former Pfizer Director of Inflammation Molecular Sciences to Spearhead Velcura Therapeutics Inflammatory Disease Initiatives
7. Sunesis Pharmaceuticals to Present Data at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
8. Astex Drug Candidates to be Featured at the 2007 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
9. Center for Molecular Medicine One of the First Midwest Labs to Offer Advanced Test for Patients with Metastatic Breast Cancer
10. Delivering Molecular Imaging Solutions Across Clinical Specialties: Siemens Showcases New Technologies at RSNA 2007
11. Center for Molecular Medicine Offers Xceed Ziplex(TM) Services to Research Community
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Molecular hula hoop
(Date:1/14/2014)... DC (PRWEB) January 14, 2014 Carahsoft ... for Thursday, January 23, 2014 at 2pm EST (11am ... Knowledge.” The topic focuses on how technology can turn ... critical decisions for government agencies. The online webinar will ...
(Date:1/14/2014)... BURLINGAME, Calif. , Jan. 14, 2014 As pet owners ... no doubt many of them wrote: "Take better care of my ... and even designer clothes and top-brand carrying cases to take the ... Pet parents might also feel compelled to buy some pricey toys ...
(Date:1/14/2014)... BETHESDA, Md. , Jan. 14, 2014  Organovo ... institutes from the National Institutes of Health (NIH) to ... more effective treatments to patients on a faster timeline. ... Translational Sciences (NCATS) and the National Eye Institute (NEI) ...
(Date:1/14/2014)... 14, 2014  RXi Pharmaceuticals Corporation (OTCQX: RXII), a ... innovative therapies addressing major unmet medical needs using ... Notice of Allowance from the United States Patent ... compounds (sd-rxRNA®), for the treatment of fibrosis. The ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 2RXi Pharmaceuticals Receives US Notice of Allowance for a Key Patent Relating to its Self-Delivering Technology with sd-rxRNAs targeting CTGF, including RXI-109, for the Treatment of Fibrotic Disorders 3
... N.J., Jan. 28 Arno Therapeutics, Inc., a,privately ... entered into,worldwide, exclusive license agreements with The Ohio ... novel, orally available,targeted therapies for cancer., Pursuant ... to several,small molecules for the treatment of cancer, ...
... Paper Provides Rationale for Continued Development of CNDO103 as ... ... Coronado Biosciences Inc. today,announced the publication of data demonstrating that the ... while,demonstrating less toxicity than Gossypol in vivo in mice., Published ...
... Jan. 28 /PRNewswire-FirstCall/ - ARIUS Research Inc., (TSX:,ARI), ... wave of,antibody therapeutics, today announced it has completed ... to discuss the upcoming IND,submission for ARH460-16-2, its ... anti-cancer antibody targeting a novel epitope of CD44,found ...
Cached Biology Technology:Arno Therapeutics Completes License Agreements for the Exclusive Rights to Novel, Targeted Cancer Compounds 2Arno Therapeutics Completes License Agreements for the Exclusive Rights to Novel, Targeted Cancer Compounds 3Study Shows Coronado Biosciences' Bcl-2 Inhibitor, Apogossypol, is More Efficacious, Less Toxic than Gossypol in Animal Models 2Study Shows Coronado Biosciences' Bcl-2 Inhibitor, Apogossypol, is More Efficacious, Less Toxic than Gossypol in Animal Models 3Arius completes Pre-IND Meeting with FDA for Lead CD44 Cancer Stem Cell Program 2Arius completes Pre-IND Meeting with FDA for Lead CD44 Cancer Stem Cell Program 3
(Date:4/17/2014)... hydrogen sulfide in order to properly multiply and form ... Center for Craniofacial Molecular Biology at the Herman Ostrow ... principal investigator on the project, said the presence of ... of calcium ions. The essential ions activate a chain ... creation of new bone tissue, and keeps the breakdown ...
(Date:4/17/2014)... in German . ... money demanded of him, he can expect his premises to ... fear of the consequences is enough to make restaurant owners ... which lay their eggs in other birds, nests. If the ... take their revenge by destroying the entire nest. Consequently, it ...
(Date:4/17/2014)... France have hit on a novel method to ... correct and most effective treatment possible., Kidney stones ... and developing world. If left untreated, apart from ... failure and other complications. In many patients treated ... a more effective pathological approach to diagnosis and ...
Breaking Biology News(10 mins):Fear of the cuckoo mafia 2Fear of the cuckoo mafia 3
... "dietary fibre". But what is dietary fibre and how do ... Structural Biology Laboratory, in collaboration with groups in Canada, the ... bacteria metabolise the complex dietary carbohydrates found in fruits and ... are about ten times more bacterial cells in the average ...
... alien world of aquatic micro-organisms just got new residents: ... has developed a class of tiny bio-hybrid machines that ... traverse the viscous fluids of biological environments on their ... Gutgsell Professor of mechanical science and engineering, the team ...
... researchers from the University of Nebraska-Lincoln, while using a ... Ice Shelf, unexpectedly discovered a new species of small ... tentacles protruding into frigid water like flowers from a ... it was really an amazing find," said Marymegan Daly, ...
Cached Biology News:York scientists investigate the fiber of our being 2Tiny swimming bio-bots boldly go where no bot has swum before 2New sea anemone species discovered in Antarctica 2New sea anemone species discovered in Antarctica 3New sea anemone species discovered in Antarctica 4
... ejector is a unique product that facilitates ... their holder. Linkage: This CLS number is ... match Cornings product number. If showing no ... Sigma-Aldrich number (Z71,314-7) or contact customer service ...
Sigmas E-TOXATE (Limulus Amebocyte Lysate) test kits are intended for the detection and semiquantitation,of endotoxins for research purposes....
... modular cleanroom for biological safety labs ... cleanliness (to Class 10/ISO 3) and ... create ultra-smooth surfaces that are easy ... radius corners simplify cleaning. Unique double-wall ...
... The Staccato Series of systems provide ... drug discovery , genomics, proteomics and drug ... three base configurations; Mini Workstation Series, Application ... Sciclone ELISA Station is a remarkably compact ...
Biology Products: