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Molecular Biomarkers for Cancer Detection and Management
Date:7/22/2013

ogy, Johns Hopkins School of Medicine; Chief Medical Officer and Founder Personal Genome Diagnostics• Jorge Nieva, MD, Oncologist and Hematologist,Billings Clinic,Billings Montana• Harry Glorikian, Managing Partner and Founder, Scientia Advisors• Paul Dempsey, Ph.D., Chief Science Officer, CynvenioBiosystems• Scott Kern, M.D., Professor of Oncology and Pathology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine• About Cambridge Healthtech Institute

TABLES • Exhibit 4.1 Screening, detection, risk, and monitoring biomarkers

• Exhibit 4.2 Prognosis and prediction biomarkers

• Exhibit 4.3 Companion diagnostic biomarkers

• Exhibit 5.1 Estimated cancer biomarker manufacturer revenues (2012) and projections (2017), by segment (US$ in billions)

• Exhibit 5.2 Selected recent cancer detection, risk, and prognostic assay deals

• Exhibit 5.3 Selected recent companion diagnostic assay deals

• Exhibit 5.4 Survey: Area of respondents' work

• Exhibit 5.5 Survey: Nature of respondents' organization

• Exhibit 5.6 Survey: Respondents' position within their organization

• Exhibit 5.7 Survey: Respondent's biomarker focus (Multiple answers permitted; n=107)

• Exhibit 5.8 Survey: Respondents' organization employs which of the following technologies for cancer biomarker detection of measurement (Multiple answers permitted; n=100)

• Exhibit 5.9 Survey: Statements regarding circulating tumor cells and nucleic acids (Multiple answers permitted; n=100)

• Exhibit 5.10 Survey: Participation in companion diagnostics (Multiple answers permitted; n=100)

• Exhibit 5.11 Survey: On a scale of 1 to 5, please rate the following entities as lik
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