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Molecular Biomarkers for Cancer Detection and Management
Date:7/22/2013

ors

• Cynvenio Biosystems

• Johns Hopkins University School of Medicine

Also provided in the report are survey results of 107 individuals who actively work in the cancer biomarker space. Results are depicted across 9 tables.

Table of Contents Executive Summary • Background and history

• Basic research

• Commercial applications

• Market dynamics

• Survey results

• Trends and conclusions

CHAPTER 1: Introduction

• Scope and contents

CHAPTER 2: Background and History

• First-generation cancer biomarkers

• Categorization of cancer biomarkers

• Disease detection biomarkers

• Prognostic biomarkers

• Companion diagnostic biomarkers

• Omic era cancer biomarkers

• Failed efforts and stumbling blocks

CHAPTER 3: Basic Research

• Screening, detection, risk, and monitoring• Screening• Prognosis and prediction• Companion Diagnostics• Metastasis• Circulating tumor cells• Exosomes• MicroRNA (miRNA)

CHAPTER 4: Commercial Applications

• Screening, detection, risk assessment, and monitoring biomarkers

• Alere

• Allegro Diagnostics

• Atossa Genetics

• Biophysical Corporation

• Exact Sciences

• Exosome Diagnostics

• Matrix-Bio

• MDx Health

• Mitomics

• Myriad Genetics

• Oncimmune

• Onconome

• Predictive Biosciences

• Sphingotec

• Prognosis and prediction biomarkers

• Agendia

• Abbott Molecular

• Atossa Genetics

• Biocept

• bioTheranostics

• DiagnoCure

• GenomeDx Biosciences

• Genomic
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