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Mirus Bio Awarded Grants & Contracts of Over $5 Million
Date:8/23/2007

molecule that triggers a natural cellular process called RNA interference. By selectively silencing the expression of a gene, one can prevent the production of disease-causing proteins. DPCs are comprised of proprietary polymers, masking agents and targeting molecules that are linked to the siRNA payload and shield it as it is injected into the bloodstream. When the DPCs attach to and are taken up by the target cells, they disassemble and release their siRNA cargo so that it becomes functionally available. This technology is currently being optimized for delivery to liver and cancer tissues, and is actively being evaluated by select partners as a therapeutic platform for multiple disease indications.

About Mirus Bio Corporation:

Mirus Bio Corporation is a leader in the fields of RNA interference and gene therapy, based upon its expertise in nucleic acid chemistry and delivery. The company's Dynamic PolyConjugates(TM) technology is being refined as an enabling platform for siRNA therapeutics. In gene therapy, the company is developing novel human therapeutics enabled by its proprietary Pathway IV(TM) hydrodynamic delivery platform. The lead program is a treatment for Muscular Dystrophy, which is being developed collaboratively with Transgene S.A. of Strasbourg, France. Finally, the company currently markets state-of-the-art DNA and siRNA transfection and labeling products to researchers worldwide.

For more information go to: http://www.mirusbio.com


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