Mirus Bio Awarded Grants & Contracts of Over ...( MADISON Wis. Aug. 23 /- Mirus Bio...)

MADISON, Wis., Aug. 23 /PRNewswire/ -- Mirus Bio Corporation today announced that it has been awarded five federal grants and contracts since January of this year totaling $5.4 million. They include:

-- Two Phase II SBIR grants totaling $2.4 million to further develop the

Company's Dynamic PolyConjugates(TM) siRNA delivery platform and

alternative nanoparticle technologies, focused primarily on improving

potency for liver applications;

[Principal Investigators Drs. D. Rozema and S. Wong]

-- One Phase II DOD contract for $1.8 million to optimize the Dynamic

PolyConjugates(TM) siRNA delivery platform for lung delivery and to

develop a treatment against respiratory infections;

[Principal Investigator Dr. H. Herweijer]

-- A Phase I SBIR grant for $0.3 million to improve gene expression

technologies; and

[Principal Investigator Dr. M. Sebestyen]

-- A previously announced Phase II SBIR grant for $0.9 million to develop

improved labeling technologies for microRNA, which is expected to lead

to new research products.

[Principal Investigator Dr. M. Watt]

"Securing this magnitude of support highlights the wide breadth of potential uses for this platform delivery technology and is a tribute to the outstanding cutting edge technology development being done by our research team," commented Jon Wolff, M.D., Mirus Bio's CSO and co-founder. "In this era of heightened competition for federal research grants, we are exceptionally pleased with this outcome and couldn't be more proud of our team as well as the grant procurement management that Dr. Hans Herweijer has provided. These funds are critical to maintaining our leadership position in nucleic acid delivery technologies."

Dynamic PolyConjugates(TM) (DPC) are an enabling platform for the targeted, systemic delivery of small interfering RNA (siRNA), a
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