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Millennium Over-Delivers on 2007 Goals and Financial Guidance
Date:2/7/2008

adjustment was $1.8 million for the three months ended December 31, 2007 on a GAAP and non-GAAP basis and $0.9 million for the three months ended December 31, 2006 on a non-GAAP basis.

(3) During the three months ended December 31, 2006, the Company recognized a $19.5 million gain upon receipt of a termination fee as a result of the termination of the support agreement with AnorMED in October 2006, net of transaction costs of approximately $5.5 million. Transaction costs are included in selling, general and administrative expenses.

Millennium Pharmaceuticals, Inc.

Reconciliation of GAAP to Non-GAAP

(unaudited)

(in thousands, except per share amounts)

Year Ended December 31, 2007

Costs and Expenses

Selling, Earnings

Research General Earnings per

and and per Share,

Development Administrative Net Share, Diluted

(1) (1) Income Basic (2)

GAAP $287,094 $189,062 $14,909 $0.05 $0.05

Adjustments to reconcile to Non-GAAP:

Stock-based

Compensation (10,674) (14,484) 25,158 0.08 0.08

Restructuring - - 12,886 0.04 0.04

Amortization of

Intangibles - - 33,950 0.10 0.10

Non-GAAP $276,420 $174,578 $86,903 $0.27 $0.27

Weighted average shares - GAAP 318,221 321,320

Weighted average shares - Non-GAAP 318,221 321,320

Year Ended December
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SOURCE Millennium Pharmaceuticals, Inc.
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