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Milestone Scientific to Report 2008 Year-End Results on Tuesday, March 17, 2009
Date:3/17/2009

Investor Conference Call Scheduled for Thursday, March 19, 2009 at 11:00 AM ET

LIVINGSTON, N.J., March 17 /PRNewswire-FirstCall/ -- Milestone Scientific Inc. (OTC Bulletin Board: MLSS), the recognized leader in advanced injection technologies, today announced that it intends to file its 2008 year-end results for the 12 months ended December 31, 2008 with the U.S. Securities & Exchange Commission on Tuesday, March 17, 2009.

Having succeeded in increasing sales for the award-winning STA Single Tooth Anesthesia System(TM) (STA System) for four consecutive quarters in 2008, the year-end results are expected to reflect record annual revenues of $6.62 million, up from $6.39 million in the prior year.

According to Joe Martin, Chief Executive Officer of Milestone, "The revised messaging and marketing platforms for the STA System that were implemented in early 2008 are now clearly resonating with dentists worldwide and attracting broad industry attention to our Company. Moreover, the clinical acclaim for the numerous tangible benefits of the STA System emanating from the dental community continues to inspire strong sales momentum. In addition, our decision to expand our distribution network from one exclusive distributor to numerous non-exclusive dental supply companies has resulted in much broader market penetration and a steady monthly increase in STA unit sales."

The Company will host a teleconference on Thursday, March 19, 2009, beginning at 11:00 AM Eastern Time, and invites all interested parties to join management in a discussion regarding Milestone's financial results, corporate progression and other meaningful developments. The conference call can be accessed by dialing toll-free 1-800-240-2430. For those unable to participate at that time, a replay of the teleconference can be accessed domestically by dialing 1-800-405-2236 and entering the passcode 11127369#. The replay will be available for 90 days.

About Milestone Scientific Inc.

Headquartered in Livingston, New Jersey, Milestone Scientific is engaged in pioneering proprietary, highly innovative technological solutions for the medical and dental markets. Central to the Company's IP platform and product development strategy is its patented CompuFlo(R) technology for the improved and painless delivery of local anesthetic. Specifically, CompuFlo is a computer-controlled, pressure sensitive infusion, perfusion, suffusion and aspiration technology, which provides real-time readouts of pressures, fluid densities and flow rates, enabling the advanced delivery and removal of a wide array of fluids. The STA Single Tooth Anesthesia System(TM), a computer-controlled local anesthesia delivery system, uses this technology to provide dentists with audible and visual signals as to in-tissue pressure. Milestone's existing painless injection systems are currently sold in 25 countries. For more information on these and other innovative Milestone products, please visit the Company's web site found at www.milesci.com and www.STAis4U.com.

Safe Harbor Statement

This press release contains forward-looking statements regarding the timing and financial impact of the Milestone's ability to implement its business plan, expected revenues and future success. These statements involve a number of risks and uncertainties and are based on assumptions involving judgments with respect to future economic, competitive and market conditions and future business decisions, all of which are difficult or impossible to predict accurately and many of which are beyond Milestone's control. Some of the important factors that could cause actual results to differ materially from those indicated by the forward-looking statements are general economic conditions, failure to achieve expected revenue growth, changes in our operating expenses, adverse patent rulings, FDA or legal developments, competitive pressures, changes in customer and market requirements and standards, and the risk factors detailed from time to time in Milestone's periodic filings with the Securities and Exchange Commission, including without limitation, Milestone's Annual Report on Form 10-KSB for the year ended December 31, 2007. The forward-looking statements in this press release are based upon management's reasonable belief as of the date hereof. Milestone undertakes no obligation to revise or update publicly any forward-looking statements for any reason.

                       FOR MORE INFORMATION, PLEASE CONTACT:
                       Elite Financial Communications Group
                           Dodi Handy, President and CEO
       For Media Inquiries: Tiffany Korkis or Kathy Addison, Directors, Elite
                                     Media Group
                     407-585-1080 or via email at mlss@efcg.net


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SOURCE Milestone Scientific Inc.
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