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MiddleBrook Pharmaceuticals Reports Fourth Quarter and Full Year 2007 Results

n restricted cash - 728,744

Net cash (used in) provided by

investing activities (834,473) 10,793,079

Cash flows from financing activities:

Proceeds from private placement of

common stock and warrants,

net of issuance costs 22,412,260 16,735,804

Proceeds from purchase of

noncontrolling interest 7,500,000 -

Proceeds from issuance of debt, net

of issue costs - 7,792,976

Payments on lines of credit (6,888,889) (2,603,524)

Proceeds from exercise of common

stock options 166,790 352,737

Net cash provided by financing

activities 23,190,161 22,277,993

Net decrease in cash and cash equivalents (12,905,023) (3,260,230)

Cash and cash equivalents, beginning

of period 14,856,738 18,116,968

Cash and cash equivalents, end of period $1,951,715 $14,856,738

SOURCE MiddleBrook Pharmaceuticals, Inc.
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