Navigation Links
Microsurgery on the brain of the fruit fly leads to new insights into irreparable nerve injuries
Date:6/3/2008

Leuven, Belgium − Every year, one million Europeans are confronted with potentially irreparable brain or spinal cord injuries resulting from traffic accidents. Because the nerves in a damaged spinal cord cannot, or cannot fully, be repaired, the patient remains (partially) paralyzed. Now, VIB scientists connected to the K.U.Leuven have become the first to successfully develop a simple model that enables the study of injured brain tissue. The researchers have perfected a technique for keeping the cultured brain of a fruit fly alive and healthy for a longer period of time. With the aid of microsurgery, this new technique enables scientists to inflict injury on certain nerve bundles for research purposes. By means of this new fruit fly model, the researchers have already succeeded in showing that the activation of a particular signaling pathway (JNK) induces the regeneration of axons. This research offers positive perspectives for patients with nerve injuries that have been irreversible up to now.

Drosophila as model organism

The Drosophila melanogaster fruit fly is an important, low-cost model organism with a 60% genetic similarity to humans. The fruit fly is playing a significant role in the elucidation of various neurological processes (such as the functioning of our memory and our sense of smell) as well as in the study of certain neurodegenerative diseases (such as Alzheimer's disease). Until recently, scientists could only use model organisms belonging to the vertebrates (e.g., the mouse) to study injuries to the nervous system and the possibility of regenerating damaged axons. However, the fruit fly model is more user-friendly and allows faster, large-scale genetic analyses.

The fruit fly brain in culture

Although the fruit fly model is used for numerous diseases, until now it has not been possible to study the repair of damaged axons with fruit flies. Indeed, the fruit fly's brain is difficult to access due to
'/>"/>

Contact: Evy Vierstraete
info@vib.be
329-244-6611
VIB (the Flanders Institute for Biotechnology)
Source:Eurekalert

Page: 1 2

Related biology technology :

1. ONCOSCIENCE AG, THE EUROPEAN PARTNER OF YM BIOSCIENCES, ANNOUNCES COMPLETION OF PATIENT ENROLLMENT IN PHASE III BRAIN CANCER TRIAL OF NIMOTUZUMAB
2. YM BioSciences USA cleared by US FDA to initiate Phase II clinical trial of nimotuzumab in children with inoperable, recurrent brain cancer
3. NIH grants $750,000 to develop device to determine temperature of neonates brain
4. InSightec Resumes Clinical Trials for Non-Invasive Treatment of Brain Tumors
5. Scientists create colorful brainbow images of the nervous system
6. Mouse Brain or Impressionist Painting?
7. GlaxoSmithKline Announces Data on TYKERB(R) (Lapatinib) Plus Capecitabine for the Treatment of HER2 Positive Breast Cancer Brain Metastases
8. Henry Ford Hospital and Rosetta Genomics to Develop MicroRNA-based Diagnostics for Brain Cancer
9. Elekta Chosen to Deliver Sophisticated Brain Mapping Technology to The Nebraska Medical Center
10. BrainCells Inc. Completes $30 Million Initial Closing of Series B Financing
11. Elekta Chosen to Deliver Sophisticated Brain Mapping Technology to Froedtert Hospital in Milwaukee
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... Calif. , Sept. 17, 2014 ... molecular diagnostics company pioneering the field of molecular cytology, ... chief operating officer. Mr. Hall joined Veracyte ... company,s commercial entry into endocrinology. Since 2012, he has ... well as managed care and billing functions. As chief ...
(Date:9/17/2014)... 2014 First antibacterial ... a truly novel class of anti-infective in ... a biopharmaceutical company developing a truly novel ... has secured £4.0m ($6.4m) to advance the ... a range of Gram-positive infections including  Clostridium ...
(Date:9/16/2014)... -- This report analyzes the worldwide markets for Bioinformatics in ... Biocontent. The report provides separate comprehensive analytics for the US, ... Europe , Asia-Pacific , ... Annual estimates and forecasts are provided for the period 2013 ... these markets. Market data and analytics are derived from primary ...
(Date:9/16/2014)... who created a deicing film for radar domes have ... coating for glass. , The new work by ... glass surfaces from windshields to skyscrapers free of ice ... (RF). , The technology was introduced this month ... and Interfaces . , The material is made ...
Breaking Biology Technology:Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 2Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 3Veracyte, Inc. Announces Promotion of Christopher M. Hall To Chief Operating Officer 4MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 2MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 3MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 4MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 5MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 6MGB Biopharma Secures £4.0m ($6.4m) to Advance its Novel Lead Antibacterial, MGB-BP-3, into Clinical Development 7Global Bioinformatics Industry 2Global Bioinformatics Industry 3Global Bioinformatics Industry 4Global Bioinformatics Industry 5Global Bioinformatics Industry 6Global Bioinformatics Industry 7Global Bioinformatics Industry 8Global Bioinformatics Industry 9Global Bioinformatics Industry 10Global Bioinformatics Industry 11Global Bioinformatics Industry 12Global Bioinformatics Industry 13Global Bioinformatics Industry 14Global Bioinformatics Industry 15Global Bioinformatics Industry 16Global Bioinformatics Industry 17Global Bioinformatics Industry 18Global Bioinformatics Industry 19Global Bioinformatics Industry 20Global Bioinformatics Industry 21Global Bioinformatics Industry 22Global Bioinformatics Industry 23Nanoribbon film keeps glass ice-free 2
... searchable database of biotech contract service providers, ... to grow the life sciences, has released ... pharmaceutical and biotechnology industries,holding significant promise for ... initiative has launched a new Web site ...
... 28 MBF Healthcare,Acquisition Corp. (Amex: MBH ... today that it and Critical Homecare,Solutions Holdings, Inc., ... and specialty infusion services, are,scheduled to present on ... Annual Global Healthcare Conference in Miami, Florida. On ...
... PCOP ), an innovator in the discovery ... advancements for two members,of its management team. Rene ... been promoted to Senior Vice President, Clinical,and Regulatory ... Ph.D., Senior,Vice President, Chemistry and Preclinical Chemical Development, ...
Cached Biology Technology:BioCrossroads Launches www.biocrossroadslinx.com and Releases Report on Biopharma Discovery and Development Contract Services 2BioCrossroads Launches www.biocrossroadslinx.com and Releases Report on Biopharma Discovery and Development Contract Services 3BioCrossroads Launches www.biocrossroadslinx.com and Releases Report on Biopharma Discovery and Development Contract Services 4MBF Healthcare Acquisition Corp. and Critical Homecare Solutions Holdings, Inc. to Present at Lehman Brothers Eleventh Annual Global Healthcare Conference 2MBF Healthcare Acquisition Corp. and Critical Homecare Solutions Holdings, Inc. to Present at Lehman Brothers Eleventh Annual Global Healthcare Conference 3Pharmacopeia Announces Management Team Changes 2Pharmacopeia Announces Management Team Changes 3Pharmacopeia Announces Management Team Changes 4Pharmacopeia Announces Management Team Changes 5
(Date:9/17/2014)... United Kingdom forms a new crime unit designed to ... last year over horse meat being passed off as ... for detecting meat adulteration. They describe their approach, which ... Journal of Agricultural and Food Chemistry . , ... a major global economic problem. But they also say ...
(Date:9/16/2014)... women in Australia is increased by lower socioeconomic ... September) in BJOG: An International Journal of ... high standards of living; however, existing research has ... indigenous and non indigenous Australians. , This case-control ... socioeconomic position on severe maternal morbidities associated with ...
(Date:9/16/2014)... The 36 Pit Fire began on September 13, 2014. ... It is currently over 2,300 acres in size and ... The 36 Pit Fire was calm Monday night due to ... establishing an anchor point and beginning to construct a fireline ... The following resources are working on the fire: , 7 ...
Breaking Biology News(10 mins):New study examines the impact of socioeconomic position & maternal morbidity in Australia 2New study examines the impact of socioeconomic position & maternal morbidity in Australia 3
... stunning example of evolution at work, scientists have now found ... in the skeletal armor of fish living in the wild. ... issue of journal Science, bring new data to long-standing debates ... is to try to understand how new animal types evolve ...
... have now found that changes in a single gene can ... in the wild. , The surprising results, announced in the ... to long-standing debates about how evolution occurs in natural habitats. ... animal types evolve in nature," said molecular geneticist David M. ...
... islands free of predators began disappearing when fur traders ... in the 18th century. The ground-nesting birds made easy ... in the journal Science now shows that the effects ... transforming the vegetation from lush grasslands to scrubby, low-growing ...
Cached Biology News:Octopuses occasionally stroll around on two arms, UC Berkeley biologists report 2Octopuses occasionally stroll around on two arms, UC Berkeley biologists report 3Octopuses occasionally stroll around on two arms, UC Berkeley biologists report 4Octopuses occasionally stroll around on two arms, UC Berkeley biologists report 5Researchers trace evolution to relatively simple genetic changes 2Researchers trace evolution to relatively simple genetic changes 3Researchers trace evolution to relatively simple genetic changes 4Researchers trace evolution to relatively simple genetic changes 5Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra 2Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra 3Introduced foxes transformed vegetation on Aleutian Islands from lush grasslands to tundra 4
Recognizes NSCL1. The molecular weight of the protein is 14,616 Daltons....
Mouse monoclonal [3G131] to Desmoglein 1 ( Abpromise for all tested applications). entrezGeneID: 1828 SwissProtID: Q02413...
Mouse monoclonal [2D7/1] to E.coli LPS ( Abpromise for all tested applications). Antigen: Tissue / cell preparation: Escherichia coli J5 cells....
COMING SOON: Anti-Mouse C5/C5b, Clone BB5.1. Monoclonal Antibody...
Biology Products: