Navigation Links
Microscopic 'clutch' puts flagellum in neutral
Date:6/19/2008

BLOOMINGTON, Ind. -- A tiny but powerful engine that propels the bacterium Bacillus subtilis through liquids is disengaged from the corkscrew-like flagellum by a protein clutch, Indiana University Bloomington and Harvard University scientists have learned. Their report appears in this week's Science.

Scientists have long known what drives the flagellum to spin, but what causes the flagellum to stop spinning -- temporarily or permanently -- was unknown.

"We think it's pretty cool that evolving bacteria and human engineers arrived at a similar solution to the same problem," said IU Bloomington biologist Daniel Kearns, who led the project. "How do you temporarily stop a motor once it gets going?"

The action of the protein they discovered, EpsE, is very similar to that of a car clutch. In cars, the clutch controls whether a car's engine is connected to the parts that spin its wheels. With the engine and gears disengaged from each other, the car may continue to move, but only because of its prior momentum; the wheels are no longer powered.

EpsE is thought to "sit down," as Kearns describes it, on the flagellum's rotor, a donut-shaped structure at the base of the flagellum. EpsE's interaction with a rotor protein called FliG causes a shape change in the rotor that disengages it from the flagellum's proton-powered engine.

The discovery of EpsE and its function was accidental. Kearns and colleagues were actually interested in learning more about the genes that cause individual cells of B. subtilis to cease wandering in solitude and take up residence in a massively communal, stationary assemblage called a biofilm. The stability of biofilms can be jeopardized by hyperactive bacterial cells whose flagella continue to spin.

"We were trying to get at how the bacterium's ability to move and biofilm formation are balanced," Kearns said. "We were looking for the genes that affected whether the cell
'/>"/>

Contact: David Bricker
brickerd@indiana.edu
812-856-9035
Indiana University
Source:Eurekalert  

Page: 1 2 3

Related biology technology :

1. Explosives at the microscopic scale produce shocking results
2. Arryx Launches HOTkit(TM) Complete for Dynamic, Scientific Manipulation of Microscopic Elements
3. BioNeutral Announces a BREAKTHROUGH in the Fight Against Bioterrorism
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Microscopic 'clutch' puts flagellum in neutral
(Date:7/11/2014)... Scottsdale, AZ (PRWEB) July 11, 2014 ... medicine device company specializing in the soft tissue ... SureLock All-Suture Anchor System for surgeries involving the ... predictable fixation through a novel, inserter-controlled deployment method. ... lead to partial deployment, anchor pull-out, or anchor ...
(Date:7/10/2014)... July 10, 2014 Terascala, the industry ... that Alan Swahn, a former vice president of product ... as vice president of marketing. Terascala’s software when combined ... NetApp create the highest performance and most reliable solutions ... to guide Terascala’s channel expansion and broaden its product ...
(Date:7/10/2014)... July 10, 2014 Senior supply chain ... professional associations, addressed the challenges of “Reducing Cost, Lead ... Industries” through strategic sourcing. Describing the partnership of the ... Supply Chain Management Institute ( SCMI) of the ... June 24 at the Kroc Institute of Peace and ...
(Date:7/10/2014)... 10, 2014 Research and Markets ( ... "International Photonic Integrated Circuit (Monolithic Integration, Hybrid ... report to their offering. ... of photonic integration traces its roots in the ... of photonic integration went unexplored and unfulfilled for ...
Breaking Biology Technology:Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 2Cayenne Medical Launches SureLock™ All-Suture Anchor System for Shoulder and Extremity Surgery 3Terascala Expands Executive Team 2Terascala Expands Executive Team 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 2Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 3Biotech & Biopharm Supply Chain Management Executives Launch BSMA in San Diego 4International Photonic Integrated Circuit (Monolithic Integration, Hybrid Integration, Module Integration) Market - Forecasts to 2019 2
... 16 Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) announced today that ... with Abbott for the exclusive worldwide development and commercialization of elagolix and the ... , The live ... at 8:45 a.m. Eastern Time ( 5:45 a.m. Pacific Time ...
... ... for certifying dentists in a new denture retention system procedure that can add 20% profit to ... (PRWEB) June 16, ... in a new denture retention system procedure that can add 20% profit to a ...
... American ... ... Association named medical writer, Rita Buckley, Writer/Owner of medical writing firm Buckley/Swartz, ... the awards for The Lehman Series Expert Panel on Weight Loss Surgery, published in ...
Cached Biology Technology:Neurocrine Biosciences Announces Conference Call and Webcast on Worldwide Agreement With Abbott on Elagolix 2Summit Dental Institute Offers A Hands-On One-Day Imtec MDI Mini Dental Implant Certification Course For Dentists 2Summit Dental Institute Offers A Hands-On One-Day Imtec MDI Mini Dental Implant Certification Course For Dentists 3Summit Dental Institute Offers A Hands-On One-Day Imtec MDI Mini Dental Implant Certification Course For Dentists 4Medical Writer Rita Buckley Wins Awards for Excellence in Medical Communication 2Medical Writer Rita Buckley Wins Awards for Excellence in Medical Communication 3
(Date:7/10/2014)... YORK , June 27, 2014  Pomerantz ... Provectus Biopharmaceuticals, Inc. ("Provectus" or the "Company")(NYSE-MKT: PVCT) ... filed in United States District Court, Middle District ... is on behalf of a class consisting of ... acquired Provectus securities between December 17, 2013 and ...
(Date:7/10/2014)... -- NXT-ID, Inc., (OTCQB: NXTD) a biometric authentication company focused on the ... was interviewed on July 1 st on the ... . Mr. Pereira discusses the company,s next generation smart wallet ... the Wocket™ aims to replace a traditional wallet with a ... tells Gino he has never heard of the Wocket ...
(Date:7/10/2014)... GOTHENBURG, Sweden , July 8, 2014 ... FPC1021 has won a new design win (DW). An Asian ... targeted date for mass production start in August 2014.   ... an Asian smartphone OEM, which has a planned date for ... received an initial ramp order of SEK 5M, for delivery ...
Breaking Biology News(10 mins):SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT 2SHAREHOLDER ALERT: Pomerantz Law Firm Announces the Filing of a Class Action against Provectus Biopharmaceuticals, Inc. and Certain Officers - PVCT 3Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 2Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 3Security and Your Money: Tampa Bay Radio Host Cedric Harris Talks to NXT-ID CEO Mr. Gino Pereira about the Wocket Smart Wallet 4FPC Wins DW and Initial Ramp Order for FPC1021 Touch Sensor for Flagship Smartphone from Asian OEM 2
... Laboratories researchers competing in an international pool of ... R&D 100 Awards in this year,s contest, and were ... awards each year to researchers whom its editors and ... most outstanding advances in applied technologies. The awards, ...
... TORONTO, ON A new study by psychologists at the ... can more accurately identify a man,s sexual orientation when looking ... of peak ovulation. Further, having romantic thoughts or a mating ... gay men. "This effect is not apparent when a ...
... in states such as Massachusetts, Wisconsin, New Jersey, Washington, ... for growers trying to realize profits in heavy cranberry ... damage can have a particularly significant negative impact in ... preferences of insects, entomologists have reported that several insects ...
Cached Biology News:Sandia captures 4 R&D 100 Awards 2Sandia captures 4 R&D 100 Awards 3Psychologists find link between ovulation and women's ability to identify heterosexual men 2Pest preferences for cranberry cultivars determined 2
... polyclonal antibody was derived from rabbit immunized ... protein domains such as antibody fragments can ... and displayed on phage using phagemid-based systems ... in the Ph.D. libraries. Anti-M13 pIII Monoclonal ...
... Ligation Kit enables ligation of ... in just 5 min at ... the DNA concentration, either circular ... (high DNA concentration) ligation products ...
... T4 Polynucleotide Kinase catalyzes ... from ATP to the 5-terminus ... bearing a 5-hydroxyl group. The ... coli, may be used to ...
...
Biology Products: