Navigation Links
Micromet to Provide Update on BiTE Antibody Development Programs at Upcoming Medical Conferences
Date:5/21/2010

BETHESDA, Md., May 21 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI), a biopharmaceutical company focused on the development and commercialization of next-generation antibodies for the treatment of cancer, today announced that updates on several of its BiTE antibody development programs will be made at two upcoming medical conferences.

Blinatumomab (MT103), the Company's lead product candidate, will be the subject of two oral presentations at the 15th Annual Congress of the European Hematology Association, to be held June 10 – 13 in Barcelona.  

In a presentation titled Prolonged Leukemia Free Survival Following Blinatumomab Treatment of Patients with Minimal Residual Disease of B Precursor ALL: Updated Results of a Phase 2 Study (abstract # 1700), Professor Ralf Bargou, Division of Hematology and Oncology, Department of Internal Medicine II, Wurzburg University Hospital, will report updated data from a Phase 2 trial of blinatumomab in patients with MRD-positive acute lymphoblastic leukemia (ALL).  Dr. Bargou, the study's principal investigator, will present updated duration of response data on 19 evaluable patients on June 12 from 4:30 – 4:45 PM CET.  Earlier results from this trial provided the basis for a pivotal trial that the Company plans to initiate in the third quarter of this year.

In a presentation titled CD3/CD19 bispecific BiTE® Antibody Blinatumomab Treatment of Non-Hodgkin Lymphoma (NHL) Patients: 60 micrograms/square meter/d by Continuous Infusion is Tolerable and Results in Durable Responses, (abstract # 433), Mariele Goebeler, Wurzburg University Hospital, will report updated results from an on-going Phase 1 trial of blinatumomab in patients with relapsed or refractory non-Hodgkin's lymphoma (NHL).  Dr. Goebeler will present an update on the experience of patients treated with blinatumomab utilizing a new dosing algorithm on June 12 from 9:00 – 9:15 AM CET.

At the 2010 American Society of Clinical Oncology Annual Meeting, to be held June 4 – 8 in Chicago, Walter Fiedler, Department of Medicine II, University Hospital Hamburg-Eppendorf will report updated results from an ongoing Phase 1 trial of MT110 in patients with advanced solid tumors.  In a poster presentation titled Phase I Safety and Pharmacology Study of the EpCAM/CD3-bispecific BiTE® Antibody MT110 in Patients with Metastatic Colorectal, Gastric or Lung Cancer (abstract # 2573), Dr. Fiedler will present interim findings from this dose escalation study on June 7 from 8:00 AM12:00 PM CST.

Abstracts can be found at www.ehaweb.org and www.asco.org.

About Blinatumomab

Blinatumomab (MT103) is a novel, next-generation monoclonal antibody designed to direct the body's cell destroying T-cells against CD19, a protein expressed on the surface of most B-cell derived non Hodgkin's lymphomas. Blinatumomab has demonstrated potent activity against adult Acute Lymphocytic Leukemia, achieving an 80% molecular response rate in a Phase 2 study. Blinatumomab was generally well-tolerated by patients in the Phase 2 study. The most frequently reported grade 3/4 adverse event was lymphopenia. All other adverse events were infrequent and transient in nature. Micromet received orphan drug designation from the EMEA for blinatumomab for the treatment of ALL in August 2009.

About Micromet, Inc.

Micromet, Inc. is a biopharmaceutical company focused on the discovery, development and commercialization of innovative antibody-based therapies for the treatment of cancer. Its product development pipeline includes novel antibodies generated with its proprietary BiTE® technology, as well as conventional monoclonal antibodies. Two of Micromet's BiTE antibodies and three of its conventional antibodies are currently in clinical trials. Micromet has collaborations with a number of leading pharmaceutical and biotechnology companies, including sanofi-aventis, Bayer Schering Pharma, Merck Serono, Boehringer Ingelheim, MedImmune and Nycomed. Additional information can be found at www.micromet-inc.com.


'/>"/>
SOURCE Micromet, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Micromet, Inc. to Present at the Sal. Oppenheim 2nd European Healthcare Conference
2. Micromet to Present at the Sachs Associates 7th Annual Biotech in Europe Investor Forum
3. Micromet Data Presented at the International AACR-NCI-EORTC Conference Support the Development of Adecatumumab (MT201) in Earlier Stage Cancer Disease Settings
4. Micromet is Presenting Four Posters on BiTE(R) Antibodies at the International AACR-NCI-EORTC Conference
5. Micromet to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference on November 7, 2007
6. Micromet, Inc. Elects Joseph P. Slattery to Board of Directors
7. Micromet to Present at the 2007 RBC Capital Markets Healthcare Conference on December 12, 2007
8. Micromet to Present at Two Upcoming Investor Conferences
9. Micromet to Present at the Susquehanna Financial Groups SIGnificant Investment Options Conference on March 4, 2008
10. Micromet, Inc. to Host Conference Call and Webcast to Discuss Fourth Quarter and Full Year 2007 Financial Results
11. Micromet, Inc. Reports Fourth Quarter and Full Year 2007 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... ... May 03, 2016 , ... Morf Media Inc ... training platform on mobile devices, today released a new interactive Food and ... Devices. The course is essential for owners or operators of places of business ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... , the sensor and data driven conferences, will take place on June 7-8, 2016, at the ... UnitedHealth's Vidya Raman-Tangella on incorporating technology -- including AR/VR, machine learning, apps, robotics and ...
(Date:5/2/2016)... , May 2, 2016 Q ... its technology partner Mannin Research Inc. will be attending ... which takes place from May 1-5, 2016 in ... be meeting with its vendors and research partners. The ... development goals and other collaborative opportunities for the MAN-01 ...
(Date:4/29/2016)... ... April 29, 2016 , ... ... is excited to announce the launch of the Proove Health Foundation . ... and education to promote the use of personalized medicine for tackling the nation’s ...
Breaking Biology Technology:
(Date:4/26/2016)... LONDON , April 26, 2016 ... EdgeVerve Systems, a product subsidiary of Infosys (NYSE: ... a partnership to integrate the Onegini mobile security ... (Logo: http://photos.prnewswire.com/prnh/20151104/283829LOGO ) The ... enhanced security to access and transact across channels. ...
(Date:4/14/2016)... AVIV, Israel , April 14, 2016 ... Behavioral Authentication and Malware Detection, today announced the appointment ... already assumed the new role. Goldwerger,s leadership ... BioCatch, on the heels of the deployment of its ... addition, BioCatch,s behavioral biometric technology, which discerns unique cognitive ...
(Date:3/23/2016)... , March 23, 2016 ... Interesse erhöhter Sicherheit Gesichts- und Stimmerkennung mit ... Inc. (NASDAQ: MESG ), ein ... dass das Unternehmen mit SpeechPro zusammenarbeitet, um ... der Finanzdienstleistungsbranche, wird die Möglichkeit angeboten, im ...
Breaking Biology News(10 mins):