Navigation Links
Micromet to Provide Update on BiTE Antibody Development Programs at Upcoming Medical Conferences
Date:5/21/2010

BETHESDA, Md., May 21 /PRNewswire-FirstCall/ -- Micromet, Inc. (Nasdaq: MITI), a biopharmaceutical company focused on the development and commercialization of next-generation antibodies for the treatment of cancer, today announced that updates on several of its BiTE antibody development programs will be made at two upcoming medical conferences.

Blinatumomab (MT103), the Company's lead product candidate, will be the subject of two oral presentations at the 15th Annual Congress of the European Hematology Association, to be held June 10 – 13 in Barcelona.  

In a presentation titled Prolonged Leukemia Free Survival Following Blinatumomab Treatment of Patients with Minimal Residual Disease of B Precursor ALL: Updated Results of a Phase 2 Study (abstract # 1700), Professor Ralf Bargou, Division of Hematology and Oncology, Department of Internal Medicine II, Wurzburg University Hospital, will report updated data from a Phase 2 trial of blinatumomab in patients with MRD-positive acute lymphoblastic leukemia (ALL).  Dr. Bargou, the study's principal investigator, will present updated duration of response data on 19 evaluable patients on June 12 from 4:30 – 4:45 PM CET.  Earlier results from this trial provided the basis for a pivotal trial that the Company plans to initiate in the third quarter of this year.

In a presentation titled CD3/CD19 bispecific BiTE® Antibody Blinatumomab Treatment of Non-Hodgkin Lymphoma (NHL) Patients: 60 micrograms/square meter/d by Continuous Infusion is Tolerable and Results in Durable Responses, (abstract # 433), Mariele Goebeler, Wurzburg University Hospital, will report updated results from an on-going Phase 1 trial of blinatumomab in patients with relapsed or refractory non-Hodgkin's lymphoma (NHL).  Dr. Goebeler will present an update on the experience of patients treated with blinatumomab utilizing a new dosing algorithm on June 12 from 9:00 – 9:15 AM CET.

At the 2010 American Society of Clinical Oncology Annual Meeting, to be held June 4 – 8 in Chicago, Walter Fiedler, Department of Medicine II, University Hospital Hamburg-Eppendorf will report updated results from an ongoing Phase 1 trial of MT110 in patients with advanced solid tumors.  In a poster presentation titled Phase I Safety and Pharmacology Study of the EpCAM/CD3-bispecific BiTE® Antibody MT110 in Patients with Metastatic Colorectal, Gastric or Lung Cancer (abstract # 2573), Dr. Fiedler will present interim findings from this dose escalation study on June 7 from 8:00 AM12:00 PM CST.

Abstracts can be found at www.ehaweb.org and www.asco.org.

About Blinatumomab

Blinatumomab (MT103) is a novel, next-generation monoclonal antibody designed to direct the body's cell destroying T-cells against CD19, a protein expressed on the surface of most B-cell derived non Hodgkin's lymphomas. Blinatumomab has demonstrated potent activity against adult Acute Lymphocytic Leukemia, achieving an 80% molecular response rate in a Phase 2 study. Blinatumomab was generally well-tolerated by patients in the Phase 2 study. The most frequently reported grade 3/4 adverse event was lymphopenia. All other adverse events were infrequent and transient in nature. Micromet received orphan drug designation from the EMEA for blinatumomab for the treatment of ALL in August 2009.

About Micromet, Inc.

Micromet, Inc. is a biopharmaceutical company focused on the discovery, development and commercialization of innovative antibody-based therapies for the treatment of cancer. Its product development pipeline includes novel antibodies generated with its proprietary BiTE® technology, as well as conventional monoclonal antibodies. Two of Micromet's BiTE antibodies and three of its conventional antibodies are currently in clinical trials. Micromet has collaborations with a number of leading pharmaceutical and biotechnology companies, including sanofi-aventis, Bayer Schering Pharma, Merck Serono, Boehringer Ingelheim, MedImmune and Nycomed. Additional information can be found at www.micromet-inc.com.


'/>"/>
SOURCE Micromet, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Micromet, Inc. to Present at the Sal. Oppenheim 2nd European Healthcare Conference
2. Micromet to Present at the Sachs Associates 7th Annual Biotech in Europe Investor Forum
3. Micromet Data Presented at the International AACR-NCI-EORTC Conference Support the Development of Adecatumumab (MT201) in Earlier Stage Cancer Disease Settings
4. Micromet is Presenting Four Posters on BiTE(R) Antibodies at the International AACR-NCI-EORTC Conference
5. Micromet to Present at the Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference on November 7, 2007
6. Micromet, Inc. Elects Joseph P. Slattery to Board of Directors
7. Micromet to Present at the 2007 RBC Capital Markets Healthcare Conference on December 12, 2007
8. Micromet to Present at Two Upcoming Investor Conferences
9. Micromet to Present at the Susquehanna Financial Groups SIGnificant Investment Options Conference on March 4, 2008
10. Micromet, Inc. to Host Conference Call and Webcast to Discuss Fourth Quarter and Full Year 2007 Financial Results
11. Micromet, Inc. Reports Fourth Quarter and Full Year 2007 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/16/2017)... 2017   Biostage, Inc. (Nasdaq: ... developing bioengineered organ implants to treat cancers and other ... today the closing on February 15, 2017 of its ... stock and warrants to purchase 20,000,000 shares of common ... offering was priced at $0.40 per share of common ...
(Date:2/16/2017)... , Feb. 16, 2017  Dermata Therapeutics, ... products to treat a variety of dermatological diseases, ... Series 1a financing and entered into a $5 ...  Dermata intends to use the capital for general ... major advancements in the treatment of serious diseases ...
(Date:2/16/2017)... Pa. , Feb. 16, 2017  Windtree ... biotechnology company focusing on developing aerosolized KL4 surfactant ... from a preclinical influenza study showed that aerosolized ... survival in a well-established preclinical animal model. The ... a growing body of evidence that supports the ...
(Date:2/16/2017)... ... February 16, 2017 , ... ... extended its industry leading Biochemistry Services specifically targeting the rapidly growing needs ... methods for the biochemical and biosimilar characterization , product-related impurity characterization, ...
Breaking Biology Technology:
(Date:2/3/2017)... A new independent identity strategy consultancy firm announces its ... to fill a critical niche in technical and policy ... Mark Crego and Janice Kephart together ... that span federal governments, the 9/11 Commission, private industry, ... has a common theme born from a shared passion ...
(Date:2/1/2017)... , February 1, 2017 IDTechEx Research, a ... emerging technology, announces the availability of a new report, Sensors ... Continue Reading ... ... and collaborative robots. Source: IDTechEx Report "Sensors for Robotics: Technologies, Markets ...
(Date:1/26/2017)...  Acuity Market Intelligence today released the 2017 ...  Acuity characterizes 2017 as a "breakout" year for ... a new understanding of the potential benefits these ... identity are often perceived as threats to privacy ... of Acuity Market intelligence. "However, taken together these ...
Breaking Biology News(10 mins):