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Micromet to Present Six Posters on Progress of BiTE Antibodies at the Annual Meeting of American Association for Cancer Research
Date:3/16/2009

SP-specific BiTE antibody at very low effector to target ratios: A new approach to treat metastatic melanoma. AACR Annual Meeting 2009, abstract no. 3248; to be presented in session 'Immunology 5' on April 21, 2009, 8:00 AM in Hall B-F, poster section 12.
  • Aigner, M. et al. (2009). Effective in vitro lysis of human melanoma cell lines by T lymphocytes redirected with a MCSP/CD3-bispecific single-chain antibody construct is independent of the expression of tumor-associated antigens gp100, MART-1, tyrosinase and NY-ESO1. AACR Annual Meeting 2009, abstract no. 4152; to be presented in session 'Immunology 6' on April 21, 2009, 1:00 PM in Hall B-F, poster section 11.

    • Abstracts can be accessed at http://www.aacr.org.

    About Micromet

    Micromet, Inc. (www.micromet-inc.com) is a biopharmaceutical company with offices in Bethesda, MD and Munich, Germany. The Company is focused on developing novel, proprietary antibodies for the treatment of cancer, inflammation and autoimmune diseases. The Company's novel antibody technology is based on its proprietary BiTE(R) antibody platform, representing a new class of antibodies that specifically activate T cells from the patient's own immune system to eliminate cancer cells or other disease related cells. Four of the Company's antibodies are currently in clinical trials, with the remainder of its product pipeline in preclinical development. The Company's lead program is a BiTE antibody known as blinatumomab, or MT103. It is in a phase 2 clinical trial for the treatment of patients with acute lymphoblastic leukemia and a phase 1 clinical trial for the treatment of patients with non-Hodgkin's lymphoma. Micromet's second BiTE antibody in clinical development is MT110, which targets the epithelial cell adhesion molecule (EpCAM). The Company owns all
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